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1
Education differentially contributes to cognitive reserve across racial/ethnic groups
Avila, Justina F.; Rentería, Miguel Arce; Jones, Richard N.. - : Wiley Periodicals, Inc., 2021. : Minnesota Population Center, 2021
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2
Impairment of memory generalization in preclinical autosomal dominant Alzheimer’s disease mutation carriers
Abstract: Fast, inexpensive and noninvasive identification of Alzheimer’s disease (AD) before clinical symptoms emerge would augment our ability to intervene early in the disease. Individuals with fully-penetrant genetic mutations causing autosomal dominant Alzheimer’s disease (ADAD) are essentially certain to develop the disease, providing a unique opportunity to examine biomarkers during the preclinical stage. Using a generalization task that has previously shown to be sensitive to medial temporal lobe pathology, we compared preclinical individuals carrying ADAD mutations to non-carrying kin to determine whether generalization (the ability to transfer previous learning to novel but familiar recombinations) is vulnerable early, before overt cognitive decline. As predicted, results revealed that preclinical ADAD mutation carriers made significantly more errors during generalization than non-carrying kin, despite no differences between groups during learning or retention. This impairment correlated with left hippocampal volume, particularly in mutation carriers. Such identification of generalization deficits in early ADAD may provide an easily implementable and potentially linguistically and culturally neutral way to identify and track cognition in ADAD.
Keyword: Article
URL: https://doi.org/10.1016/j.neurobiolaging.2018.01.022
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871602/
http://www.ncbi.nlm.nih.gov/pubmed/29494861
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3
Culture and Cognition : The Relationship between Self- Construals and Cognitive Fluency
Medina Luis D.. - : eScholarship, University of California, 2015
In: Medina Luis D.(2015). Culture and Cognition : The Relationship between Self- Construals and Cognitive Fluency. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/36z392sr (2015)
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4
Brain lateralization of complex movement: Neuropsychological evidence from unilateral stroke
In: Brain and cognition. - San Diego, Calif. [u.a.] : Elsevier Science 84 (2014) 1, 164-169
OLC Linguistik
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