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Atypical Brain Asymmetry in Autism-A Candidate for Clinically Meaningful Stratification
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In: Floris, Dorothea L; Wolfers, Thomas; Zabihi, Mariam; Holz, Nathalie E; Zwiers, Marcel P; Charman, Tony; Tillmann, Julian; Ecker, Christine; Dell'Acqua, Flavio; Banaschewski, Tobias; Moessnang, Carolin; Baron-Cohen, Simon; Holt, Rosemary; Durston, Sarah; Loth, Eva; Murphy, Declan G M; Marquand, Andre; Buitelaar, Jan K; Beckmann, Christian F; EU-AIMS Longitudinal European Autism Project Group (2021). Atypical Brain Asymmetry in Autism-A Candidate for Clinically Meaningful Stratification. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 6(8):802-812. (2021)
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Temporal information transfer by electrical stimulation in auditory implants ; Zeitliche Informationsübertragung durch elektrische Stimulation bei Hörprothesen
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Knowledge, attitudes, and beliefs regarding molar incisor hypomineralisation amongst Swiss dental students
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In: Hamza, Blend; Elhennawy, Karim; van Waes, Hubertus; Papageorgiou, Spyridon N (2021). Knowledge, attitudes, and beliefs regarding molar incisor hypomineralisation amongst Swiss dental students. BMC Oral Health, 21:548. (2021)
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Adults with a history of recreational cannabis use have altered speech production
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Körper-Sprache: Sprachliche Repräsentation von Körpern bei Patientinnen und Patienten mit Essstörungen
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Eine dreifach nutzbare Aufgabe für pädiatrische fMRT-Studien zur kombinierten Untersuchung von sprachlicher, visueller und motorischer Domäne
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Evaluation der perzeptiven Testlistenäquivalenz des Freiburger Einsilbertests mit Normalhörenden aus dem südostdeutschen Sprachraum
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Exploring how Syrian women manage their health after migration to Germany: results of a qualitative study
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Bestimmung des relativen Sprachinformationsgehalts in einzelnen Frequenzbändern für das Sprachmaterial des Göttinger Satztests
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Exploring how Syrian women manage their health after migration to Germany: results of a qualitative study
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Preoperative Assessment of Language Dominance through Combined Resting-State and Task-Based Functional Magnetic Resonance Imaging
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Investigating the response scale of the EORTC QLQ-C30 in German cancer patients and a population survey
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The german version of the mobile app rating scale (MARS-G): development and validation study ...
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Effects of theta burst stimulation over the dorsolateral prefrontal cortex on language switching - A behavioral and ERP study. ...
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‘I interact therefore I am’ ... : human becoming in and through social interaction ...
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Fully automatic segmentation of glottis and vocal folds in endoscopic laryngeal high-speed videos using a deep Convolutional LSTM Network
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In: PLOS One (2020)
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Follow-Up in Aphasia Caused by Acute Stroke in a Prospective, Randomized, Clinical, and Experimental Controlled Noninvasive Study With an iPad-Based App (Neolexon®): Study Protocol of the Lexi Study
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Feil, Katharina; Erbert, Franziska; Dieterich, Marianne; Müller, Katharina; Young, Peter; Becker, Regina; Lehner, Katharina; Pfahler, Angelika; Kellert, Lars; Rheinwald, Marika; Thunstedt, Dennis C.; Kuepper, Clemens
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In: Frontiers in Neurology (2020)
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Abstract:
Rationale: Treatment of aphasia is still challenging for clinicians and patients. So far, there is proven evidence for “face-to-face” speech therapy. However, the digital age potentially offers new and complementary strategies that may add to treatment outcome in a cost-effective way. Neolexon® is a commercial tablet-based software for treatment of aphasia, which can be applied with the help of a therapist or as self-training by the patient. Aims and hypothesis: In the Lexi study, we aim to determine whether treatment with Neolexon® is superior to standard therapy in acute post-stroke aphasia. Sample size estimates: A sample size of 180 patients, 90 for each group, will be included with an assumed dropout rate of ~20%. Methods and design: Prospective, randomized, parallel group, open-label, blinded-endpoint clinical, and experimental controlled non-invasive trial (PROBE). Adult German native speakers with acute aphasia after stroke are included. Computer-generated, blocked, and stratified randomization by aphasia severity will assign patients to one of two groups: 4 weeks of either standard logopedic speech therapy or logopedic speech therapy with the app version of Neolexon®. Both groups will be instructed in self-training: the frequency and duration of self-training will be documented. Screening for aphasia will be performed using the Language Screening Test (LAST). The severity of aphasia in general and in subitems will be assessed using the Bielefelder Aphasie Screening (BIAS) and the Aphasia Check List (ACL). Follow-up will be assessed after 3 months. Study outcomes: Based on the consensus in our study team, we considered a 10% mean difference in the change of percentile rank (PR) of BIAS to be a minimal and clinically important difference. The primary endpoint is defined as a significant difference in BIAS comparing the two groups. Differences in quality of life, Beck Depression Inventory (BDI), and modified Ranking Scale (mRS) will be evaluated as secondary outcome parameters. Discussion: This trial will determine whether speech therapy with the use of Neolexon® is superior to standard logopedic therapy. Subgroups with the greatest response to Neolexon® will be described. The trial was prospectively registered on the “EU Clinical Trials Register” (NCT04080817).
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Keyword:
ddc:610; Medizin
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URL: https://epub.ub.uni-muenchen.de/87451/ http://nbn-resolving.de/urn:nbn:de:bvb:19-epub-87451-1 https://epub.ub.uni-muenchen.de/87451/1/fneur-11-00294.pdf https://doi.org/10.3389/fneur.2020.00294
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Bayesian spatial modelling of childhood cancer incidence in Switzerland using exact point data: a nationwide study during 1985-2015. ...
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