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The Impact of Game Elements on Learner Motivation: Influence of Initial Motivation and Player Profile
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In: EISSN: 1939-1382 ; IEEE Transactions on Learning Technologies ; https://hal.univ-lyon2.fr/hal-03579428 ; IEEE Transactions on Learning Technologies, Institute of Electrical and Electronics Engineers, In press, ⟨10.1109/TLT.2022.3153239⟩ (2022)
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Source or target first? Comparison of two post-editing strategies with translation students
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In: https://hal.archives-ouvertes.fr/hal-03546151 ; 2022 (2022)
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“Institution” and “institute”: tendency to the “false substitution” of concepts ...
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Potential of automatic speech processing technologies for early detection of oral language disorders: a meta-analytic review ...
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К ВОПРОСУ О МЕЖКУЛЬТУРНОЙ КОММУНИКАЦИИ В СФЕРЕ ДЕЛОВОГО ОБЩЕНИЯ ... : ON THE ISSUE OF INTERCULTURAL COMMUNICATION IN THE FIELD OF BUSINESS COMMUNICATION ...
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К ВОПРОСУ О ЛИНГВИСТИЧЕСКОМ НЕРАВЕНСТВЕ В ПОЛИЛИНГВАЛЬНОМ ОБРАЗОВАТЕЛЬНОМ ПРОСТРАНСТВЕ ... : ON THE ISSUE OF LINGUISTIC INEQUALITY IN A MULTILINGUAL EDUCATIONAL ENVIRONMENT ...
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A Systematic Review of Studies Describing the Effectiveness, Acceptability, and Potential Harms of Place-Based Interventions to Address Loneliness and Mental Health Problems
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In: International Journal of Environmental Research and Public Health; Volume 19; Issue 8; Pages: 4766 (2022)
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Analysis of Faecal Microbiota and Small ncRNAs in Autism: Detection of miRNAs and piRNAs with Possible Implications in Host–Gut Microbiota Cross-Talk
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In: Nutrients; Volume 14; Issue 7; Pages: 1340 (2022)
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Abstract:
Intestinal microorganisms impact health by maintaining gut homeostasis and shaping the host immunity, while gut dysbiosis associates with many conditions, including autism, a complex neurodevelopmental disorder with multifactorial aetiology. In autism, gut dysbiosis correlates with symptom severity and is characterised by a reduced bacterial variability and a diminished beneficial commensal relationship. Microbiota can influence the expression of host microRNAs that, in turn, regulate the growth of intestinal bacteria by means of bidirectional host-gut microbiota cross-talk. We investigated possible interactions among intestinal microbes and between them and host transcriptional modulators in autism. To this purpose, we analysed, by “omics” technologies, faecal microbiome, mycobiome, and small non-coding-RNAs (particularly miRNAs and piRNAs) of children with autism and neurotypical development. Patients displayed gut dysbiosis related to a reduction of healthy gut micro- and mycobiota as well as up-regulated transcriptional modulators. The targets of dysregulated non-coding-RNAs are involved in intestinal permeability, inflammation, and autism. Furthermore, microbial families, underrepresented in patients, participate in the production of human essential metabolites negatively influencing the health condition. Here, we propose a novel approach to analyse faeces as a whole, and for the first time, we detected miRNAs and piRNAs in faecal samples of patients with autism.
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Keyword:
autism spectrum disorders; gene-environment interaction; host–gut microbiota cross-talk; microbiome; microRNAs; multi-omics; mycobiome; piRNAs
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URL: https://doi.org/10.3390/nu14071340
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Dual-Cameras-Based Driver’s Eye Gaze Tracking System with Non-Linear Gaze Point Refinement
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In: Sensors; Volume 22; Issue 6; Pages: 2326 (2022)
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How Does Toddlers’ Engagement in Literacy Activities Influence Their Language Abilities?
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In: International Journal of Environmental Research and Public Health; Volume 19; Issue 1; Pages: 526 (2022)
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Ecocultural or Biocultural? Towards Appropriate Terminologies in Biocultural Diversity
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In: Biology; Volume 11; Issue 2; Pages: 207 (2022)
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Vedantic Basis and Praxis of the Integral Advaita of Sri Aurobindo
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In: Monsoon: South Asian Studies Association Journal (2022)
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Tusha Hiti: The Origin and Significance of the Name
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In: Monsoon: South Asian Studies Association Journal (2022)
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Diversity, Equity, and Inclusion: Perspectives from Contemporary India and 6th Century Jain Yoga
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In: Monsoon: South Asian Studies Association Journal (2022)
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Ganges in Indian Sculpture and Literature: Mythology and Personification
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In: Monsoon: South Asian Studies Association Journal (2022)
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Digital and Spatial Humanities Mapping: Eurasia-Pacific Early Trade and Belief Linkages
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In: Monsoon: South Asian Studies Association Journal (2022)
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