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Effect Sizes of Deletions and Duplications on Autism Risk Across the Genome
In: ISSN: 0002-953X ; EISSN: 1535-7228 ; American Journal of Psychiatry ; https://hal-pasteur.archives-ouvertes.fr/pasteur-03325371 ; American Journal of Psychiatry, American Psychiatric Publishing, 2021, 178 (1), pp.87-98. ⟨10.1176/appi.ajp.2020.19080834⟩ (2021)
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2
Neural and behavioural indices of face processing in siblings of children with autism spectrum disorder (ASD): a longitudinal study from infancy to mid-childhood
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3
Predictors of longer-term development of expressive language in two independent longitudinal cohorts of language-delayed preschoolers with Autism Spectrum Disorder ...
Bal, Vanessa; Fok, Megan; Georgiades, Stelios. - : Rutgers University, 2020
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4
Neural and behavioural indices of face processing in siblings of children with autism spectrum disorder (ASD): A longitudinal study from infancy to mid-childhood
In: Cortex (2020)
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5
Neural and behavioural indices of face processing in siblings of children with autism spectrum disorder (ASD): a longitudinal study from infancy to mid-childhood
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6
Assuming ability of youth with autism: Synthesis of methods capturing the first-person perspectives of children and youth with disabilities
Tesfaye, Rackeb; Courchesne, Valerie; Yusuf, Afiqah. - : SAGE Publications, 2019
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7
Predictors of longer-term development of expressive language in two independent longitudinal cohorts of language-delayed preschoolers with Autism Spectrum Disorder
In: J Child Psychol Psychiatry (2019)
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8
Narrowing Perceptual Sensitivity to the Native Language in Infancy: Exogenous Influences on Developmental Timing
Elsabbagh, Mayada; Hohenberger, Annette; Campos, Ruth. - : Saarländische Universitäts- und Landesbibliothek, 2018
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9
Randomised trial of a parent-mediated intervention for infants at high risk for autism: longitudinal outcomes to age 3 years
Green, J.; Pickles, A.; Pasco, G.. - : Wiley, 2017
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10
Randomised trial of a parent-mediated intervention for infants at high risk for autism: longitudinal outcomes to age 3 years. ...
Green, Jonathan; Pickles, Andrew; Pasco, Greg. - : Apollo - University of Cambridge Repository, 2017
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11
Randomised trial of a parent-mediated intervention for infants at high risk for autism: longitudinal outcomes to age 3 years.
British Autism Study of Infant Siblings (BASIS) Team; Charman, Tony; Jones, Emily. - : Wiley, 2017. : J Child Psychol Psychiatry, 2017
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12
Randomised trial of a parent-mediated intervention for infants at high risk for autism: Longitudinal outcomes to age 3 years
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13
Early development of infants with neurofibromatosis type 1: A case series
Abstract: Background: Prospective studies of infants at familial risk for autism spectrum disorder (ASD) have yielded insights into the earliest signs of the disorder but represent heterogeneous samples of unclear aetiology. Complementing this approach by studying cohorts of infants with monogenic syndromes associated with high rates of ASD offers the opportunity to elucidate the factors that lead to ASD. Methods: We present the first report from a prospective study of ten 10-month-old infants with neurofibromatosis type 1 (NF1), a monogenic disorder with high prevalence of ASD or ASD symptomatology. We compared data from infants with NF1 to a large cohort of infants at familial risk for ASD, separated by outcome at age 3 of ASD (n = 34), atypical development (n = 44), or typical development (n = 89), and low-risk controls (n = 75). Domains assessed at 10 months by parent report and examiner observation include cognitive and adaptive function, sensory processing, social engagement, and temperament. Results: Infants with NF1 showed striking impairments in motor functioning relative to low-risk infants; this pattern was seen in infants with later ASD from the familial cohort (HR-ASD). Both infants with NF1 and the HR-ASD group showed communication delays relative to low-risk infants. Conclusions: Ten-month-old infants with NF1 show a range of developmental difficulties that were particularly striking in motor and communication domains. As with HR-ASD infants, social skills at this age were not notably impaired. This is some of the first information on early neurodevelopment in NF1. Strong inferences are limited by the sample size, but the findings suggest implications for early comparative developmental science and highlight motor functioning as an important domain to inform the development of relevant animal models. The findings have clinical implications in indicating an important focus for early surveillance and remediation in this early diagnosed genetic disorder.
Keyword: Activities of Daily Living; Adaptive functioning; Autism; Autism Spectrum Disorder; Cognition; Communication; Development; Developmental Biology; Developmental Neuroscience; Female; Humans; Infant; Language Development Disorders; Male; Molecular Biology; Motor Activity; Neurofibromatosis 1; NF1; Prospective longitudinal; Prospective Studies; Psychiatry and Mental Health; Risk; Sensory processing; Social engagement; Temperament; Translational neurodevelopment
URL: http://hdl.handle.net/2318/1669415
https://doi.org/10.1186/s13229-017-0178-0
http://www.molecularautism.com/
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14
Randomised trial of a parent-mediated intervention for infants at high risk for autism: longitudinal outcomes to age 3 years
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15
Narrowing perceptual sensitivity to the native language in infancy: exogenous influences on developmental timing
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16
Narrowing perceptual sensitivity to the native language in infancy: exogenous influences on developmental timing
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17
The importance of the eyes: communication skills in infants of blind parents
Senju, Atsushi; Tucker, Leslie A.; Pasco, G.. - : The Royal Society, 2013
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18
Narrowing Perceptual Sensitivity to the Native Language in Infancy: Exogenous Influences on Developmental Timing
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19
The importance of the eyes: communication skills in infants of blind parents
Senju, Atsushi; Tucker, Leslie; Pasco, Greg. - : The Royal Society, 2013
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20
Atypical audiovisual speech integration in infants at risk for autism
Guiraud, J.A.; Tomalski, Przemyslaw; Kushnerenko, Elena. - : Public Library of Science, 2012
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