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Examining the presence and nature of delusions in Alzheimer's disease and frontotemporal dementia syndromes
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Evidence for a pervasive autobiographical memory impairment in Logopenic Progressive Aphasia. ...
Ramanan, Siddharth; Foxe, David; El-Omar, Hashim. - : Apollo - University of Cambridge Repository, 2021
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Evidence for a pervasive autobiographical memory impairment in Logopenic Progressive Aphasia.
Ramanan, Siddharth; Foxe, David; El-Omar, Hashim. - : Elsevier BV, 2021. : Neurobiol Aging, 2021
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Establishing two principal dimensions of cognitive variation in Logopenic Progressive Aphasia ...
Abstract: Logopenic Progressive Aphasia (LPA) is a neurodegenerative syndrome characterised by sentence repetition and naming difficulties arising from left-lateralised temporoparietal atrophy. Clinical descriptions of LPA largely concentrate on profiling language deficits, however, accumulating evidence points to the presence of cognitive deficits, even on tasks with minimal language demands. Although non-linguistic cognitive deficits in LPA are thought to scale with disease severity, patients at discrete stages of language dysfunction display overlapping cognitive profiles, suggesting individual-level variation in cognitive performance, independent of primary language dysfunction. To address this issue, we used principal component analysis to decompose individual-level variation in cognitive performance in 43 well-characterised LPA patients who underwent multi-domain neuropsychological assessments and structural neuroimaging. The principal component analysis solution revealed the presence of two, statistically ... : This work was supported in part by funding to Forefront, a collaborative research group specialized to the study of frontotemporal dementia and motor neurone disease, from the National Health and Medical Research Council (NHMRC) of Australia program grant (APP1037746) and the Australian Research Council (ARC) Centre of Excellence in Cognition and its Disorders Memory Program (CE110001021). Siddharth Ramanan is supported by a Faculty of Science Ph.D. Research Scholarship from The University of Sydney. Olivier Piguet is supported by an NHMRC Senior Research Fellowship (APP1103258). Muireann Irish is supported by an ARC Future Fellowship (FT160100096) and an ARC Discovery Project (DP180101548). Matthew A. Lambon Ralph is supported by a UKRI-MRC Programme Grant (MR/R023883/1) and an ERC Advanced grant (GAP: 670428 - BRAIN2MIND_NEUROCOMP). ...
URL: https://www.repository.cam.ac.uk/handle/1810/311571
https://dx.doi.org/10.17863/cam.58663
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Establishing two principal dimensions of cognitive variation in Logopenic Progressive Aphasia
Ramanan, Siddharth; Roquet, Daniel; Goldberg, Zoë-lee. - : Oxford University Press, 2020. : Brain Communications, 2020
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6
Dementia diagnosis in seven languages: the Addenbrooke’s Cognitive Examination-III in India
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7
Establishing two principal dimensions of cognitive variation in logopenic progressive aphasia
In: Brain Commun (2020)
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8
Correlates of Anomia in non-semantic Variants of Primary Progressive Aphasia Converge over Time ...
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Correlates of Anomia in non-semantic Variants of Primary Progressive Aphasia Converge over Time ...
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10
Prevalence of Amyloid-β Pathology in Distinct Variants of Primary Progressive Aphasia
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11
Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia: Amyloid-β Pathology in PPA
In: Annals of Neurology. - 84, 5 (2018) , 729-740, ISSN: 0364-5134 (2018)
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12
External details revisited – A new taxonomy for coding ‘non-episodic’ content during autobiographical memory retrieval
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13
Cerebellar Atrophy and Its Contribution to Cognition in Frontotemporal Dementias
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14
Common and divergent neural correlates of anomia in amnestic and logopenic presentations of Alzheimer's disease
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15
Neural Substrates of Semantic Prospection – Evidence from the Dementias
Irish, Muireann; Eyre, Nadine; Dermody, Nadene. - : Frontiers Media S.A., 2016
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16
An Update on semantic dementia : genetics, imaging, and pathology
Landin-Romero, Ramon; Tan, Rachel; Hodges, John R. - : BioMed Central, 2016
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17
'Language of the past' - exploring past tense disruption during autobiographical narration in neurodegenerative disorders
Irish, Muireann; Kamminga, Jody; Addis, Donna Rose. - : John Wiley & Sons, 2016
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18
The longitudinal interplay of behavorial symptoms and functional decline in frontotemporal dementia
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19
Syntactic comprehension deficits across the FTD-ALS continuum
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Non-verbal episodic memory deficits in primary progressive aphasias are highly predictive of underlying amyloid pathology
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