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1
Developmental screening using caregiver report: an evaluation of screening tools and childhood developmental delays in South Africa ...
Abdoola, Shabnam. - : University of Pretoria, 2022
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2
Developmental screening using caregiver report: an evaluation of screening tools and childhood developmental delays in South Africa ...
Abdoola, Shabnam. - : University of Pretoria, 2022
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3
Still connecting the dots : an investigation into infants' attentional bias to threat using an eye-tracking task
Sareen, Sinia; Doyle, Frances L. (R20426); Kemp, Lindsay J.. - : U.S., John Wiley & Sons, 2022
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4
“Do environmental contaminant substances have potential negative effect on children´s speech, language, and communication? A systematic review” ...
Stübner, Charlotte. - : Open Science Framework, 2021
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5
Shared Language Erosion: Rethinking Immigrant Family Communication and Impacts on Youth Development
In: Human Development and Family Studies Publications (2021)
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6
[In Press] Sympathetic nervous system functioning during the face-to-face still-face paradigm in the first year of life
Klein, Louis; Doyle, Frances L. (R20426); Northam, Jaimie C.. - : U.K., Cambridge University Press, 2021
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7
Expressive language development in adolescents with Down syndrome and fragile X syndrome: change over time and the role of family-related factors.
In: Journal of neurodevelopmental disorders, vol 12, iss 1 (2020)
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8
Health comorbidities and cognitive abilities across the lifespan in Down syndrome. ...
Startin, Carla M; D'Souza, Hana; Ball, George. - : Apollo - University of Cambridge Repository, 2020
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9
Health comorbidities and cognitive abilities across the lifespan in Down syndrome.
Startin, Carla M; D'Souza, Hana; Ball, George. - : Springer Science and Business Media LLC, 2020. : J Neurodev Disord, 2020
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10
Pathogenic variants in USP7 cause a neurodevelopmental disorder with speech delays, altered behavior, and neurologic anomalies.
In: Genetics in medicine : official journal of the American College of Medical Genetics, vol 21, iss 8 (2019)
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11
Time Points: A Gestural Study of the Development of Space-Time Mappings.
In: Cognitive science, vol 43, iss 12 (2019)
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12
Neuroscientific insights into the development of analogical reasoning.
In: Developmental science, vol 21, iss 2 (2018)
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13
Community-Based Health and Exposure Study around Urban Oil Developments in South Los Angeles.
In: International journal of environmental research and public health, vol 15, iss 1 (2018)
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14
Finding meaning in a noisy world: exploring the effects of referential ambiguity and competition on 2·5-year-olds' cross-situational word learning.
In: Journal of child language, vol 44, iss 3 (2017)
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15
Haploinsufficiency of the E3 ubiquitin-protein ligase gene TRIP12 causes intellectual disability with or without autism spectrum disorders, speech delay, and dysmorphic features
In: ISSN: 1432-1203 ; Hum Genet ; https://hal.archives-ouvertes.fr/hal-02104155 ; Hum Genet, 2017, 136, pp.377-386. ⟨10.1007/s00439-017-1763-1⟩ ; https://link.springer.com/article/10.1007/s00439-017-1763-1 (2017)
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16
Language Development and Impairment in Children With Mild to Moderate Sensorineural Hearing Loss. ...
Halliday, Lorna; Tuomainen, Outi; Rosen, Stuart. - : Apollo - University of Cambridge Repository, 2017
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17
Language Development and Impairment in Children With Mild to Moderate Sensorineural Hearing Loss.
Halliday, Lorna; Tuomainen, Outi; Rosen, Stuart. - : American Speech Language Hearing Association, 2017. : J Speech Lang Hear Res, 2017
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18
Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children.
In: Brain imaging and behavior, vol 10, iss 1 (2016)
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19
Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children.
In: Brain imaging and behavior, vol 10, iss 1 (2016)
Abstract: Dyslexia and language impairment (LI) are complex traits with substantial genetic components. We recently completed an association scan of the DYX2 locus, where we observed associations of markers in DCDC2, KIAA0319, ACOT13, and FAM65B with reading-, language-, and IQ-related traits. Additionally, the effects of reading-associated DYX3 markers were recently characterized using structural neuroimaging techniques. Here, we assessed the neuroimaging implications of associated DYX2 and DYX3 markers, using cortical volume, cortical thickness, and fractional anisotropy. To accomplish this, we examined eight DYX2 and three DYX3 markers in 332 subjects in the Pediatrics Imaging Neurocognition Genetics study. Imaging-genetic associations were examined by multiple linear regression, testing for influence of genotype on neuroimaging. Markers in DYX2 genes KIAA0319 and FAM65B were associated with cortical thickness in the left orbitofrontal region and global fractional anisotropy, respectively. KIAA0319 and ACOT13 were suggestively associated with overall fractional anisotropy and left pars opercularis cortical thickness, respectively. DYX3 markers showed suggestive associations with cortical thickness and volume measures in temporal regions. Notably, we did not replicate association of DYX3 markers with hippocampal measures. In summary, we performed a neuroimaging follow-up of reading-, language-, and IQ-associated DYX2 and DYX3 markers. DYX2 associations with cortical thickness may reflect variations in their role in neuronal migration. Furthermore, our findings complement gene expression and imaging studies implicating DYX3 markers in temporal regions. These studies offer insight into where and how DYX2 and DYX3 risk variants may influence neuroimaging traits. Future studies should further connect the pathways to risk variants associated with neuroimaging/neurocognitive outcomes.
Keyword: 2.1 Biological and endogenous factors; Adolescent; Basic Behavioral and Social Science; Behavioral and Social Science; Brain; Brain Disorders; Cell Adhesion Molecules; Child; Clinical Research; Cohort Studies; Cross-Sectional Studies; Diffusion Magnetic Resonance Imaging; Diffusion Tensor Imaging; Dyslexia; DYX2; DYX3; Experimental Psychology; Genetic Predisposition to Disease; Genetics; Genotyping Techniques; Humans; Imaging-genetics; KIAA0319; Language Development Disorders; Language impairment; Medical and Health Sciences; Mental health; Nerve Tissue Proteins; Neurosciences; Organ Size; Pediatric; Pediatric Imaging Neurocognition Genetics Study; Polymorphism; Preschool; Prevention; Proteins; Psychology and Cognitive Sciences; Single Nucleotide; Thiolester Hydrolases; White Matter; Young Adult
URL: https://escholarship.org/uc/item/7rh1571s
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20
Language problems among maltreated children : A meta-analytic review.
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