• Refine your search:
  • 
    Keyword
  • 
    Creator / Publisher:
    
    • Jack, Clifford R. (37)
    • Josephs, Keith A. (34)
    • Whitwell, Jennifer L. (33)
    • Duffy, Joseph R. (31)
    • Machulda, Mary M. (29)
    • Senjem, Matthew L. (27)
    • Strand, Edythe A. (21)
    • Lowe, Val J. (18)
    • Petersen, Ronald C. (18)
    • Clark, Heather M. (13)
    •   more
  • 
    Year
  • 
    Medium
  • 
    Type:
    
    • Article (42)
  • 
    BLLDB-Access

Search in the Catalogues and Directories

All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 Hits 1 – 20 of 42 1 Tractography of supplementary motor area projections in progressive speech apraxia and aphasia Valls Carbo, Adrian; Reid, Robert I.; Tosakulwong, Nirubol; Weigand, Stephen D.; Duffy, Joseph R.; Clark, Heather M.; Utianski, Rene L.; Botha, Hugo; Machulda, Mary M.; Strand, Edythe A.; Schwarz, Christopher G.; Jack, Clifford R.; Josephs, Keith A.; Whitwell, Jennifer L. In: Neuroimage Clin (2022) Abstract: Progressive apraxia of speech (AOS) is a motor speech disorder affecting the ability to produce phonetically or prosodically normal speech. Progressive AOS can present in isolation or co-occur with agrammatic aphasia and is associated with degeneration of the supplementary motor area. We aimed to assess breakdowns in structural connectivity from the supplementary motor area in patients with any combination of progressive AOS and/or agrammatic aphasia to determine which supplementary motor area tracts are specifically related to these clinical symptoms. Eighty-four patients with progressive AOS or progressive agrammatic aphasia were recruited by the Neurodegenerative Research Group and underwent neurological, speech/language, and neuropsychological testing, as well as 3 T diffusion magnetic resonance imaging. Of the 84 patients, 36 had apraxia of speech in isolation (primary progressive apraxia of speech, PPAOS), 40 had apraxia of speech and agrammatic aphasia (AOS-PAA), and eight had agrammatic aphasia in isolation (progressive agrammatic aphasia, PAA). Tractography was performed to identify 5 distinct tracts connecting to the supplementary motor area. Fractional anisotropy and mean diffusivity were assessed at 10 positions along the length of the tracts to construct tract profiles, and median profiles were calculated for each tract. In a case-control comparison, decreased fractional anisotropy and increased mean diffusivity were observed along the supplementary motor area commissural fibers in all three groups compared to controls. PPAOS also had abnormal diffusion in tracts from the supplementary motor area to the putamen, prefrontal cortex, Broca’s area (frontal aslant tract) and motor cortex, with greatest abnormalities observed closest to the supplementary motor area. The AOS-PAA group showed abnormalities in the same set of tracts, but with greater involvement of the supplementary motor area to prefrontal tract compared to PPAOS. PAA showed abnormalities in the left prefrontal and frontal aslant tracts compared to both other groups, with PAA showing greatest abnormalities furthest from the supplementary motor area. Severity of AOS correlated with tract metrics in the supplementary motor area commissural and motor cortex tracts. Severity of aphasia correlated with the frontal aslant and prefrontal tracts. These findings provide insight into how AOS and agrammatism are differentially related to disrupted diffusivity, with progressive AOS associated with abnormalities close to the supplementary motor area, and the frontal aslant and prefrontal tracts being particularly associated with agrammatic aphasia. Keyword: Regular Article URL: https://doi.org/10.1016/j.nicl.2022.102999 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8987652/ BASE Hide details 2 Posterior cortical atrophy phenotypic heterogeneity revealed by decoding (18)F-FDG-PET Townley, Ryan A; Botha, Hugo; Graff-Radford, Jonathan... In: Brain Commun (2021) BASE Show details 3 Changing the face of neuroimaging research: Comparing a new MRI de-facing technique with popular alternatives Schwarz, Christopher G.; Kremers, Walter K.; Wiste, Heather J.... In: Neuroimage (2021) BASE Show details 4 A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech Josephs, Keith A.; Duffy, Joseph R.; Clark, Heather M.... In: Nat Commun (2021) BASE Show details 5 Longitudinal neuroimaging biomarkers differ across Alzheimer’s disease phenotypes Sintini, Irene; Graff-Radford, Jonathan; Senjem, Matthew L... In: Brain (2020) BASE Show details 6 Association of amyloid angiopathy with microbleeds in logopenic progressive aphasia: an imaging-pathology study Buciuc, Marina; Duffy, Joseph R.; Machulda, Mary M.... In: Eur J Neurol (2020) BASE Show details 7 Longitudinal anatomic, functional, and molecular characterization of Pick disease phenotypes Whitwell, Jennifer L.; Tosakulwong, Nirubol; Schwarz, Christopher C.... In: Neurology (2020) BASE Show details 8 An Evaluation of the Progressive Supranuclear Palsy Speech/Language Variant Whitwell, Jennifer L.; Stevens, Chase A.; Duffy, Joseph R.... In: Mov Disord Clin Pract (2019) BASE Show details 9 Clinical and Neuroimaging Characteristics of Clinically Unclassifiable Primary Progressive Aphasia Utianski, Rene L.; Botha, Hugo; Martin, Peter R.... In: Brain Lang (2019) BASE Show details 10 The influence of β-amyloid on [(18)F]AV-1451 in semantic variant of primary progressive aphasia Whitwell, Jennifer L.; Martin, Peter R.; Duffy, Joseph R.. - : Lippincott Williams & Wilkins, 2019 BASE Show details 11 Patterns of Neuropsychological Dysfunction and Cortical Volume Changes in Logopenic Aphasia Owens, Tyler E.; Machulda, Mary M.; Duffy, Joseph R.. - 2018 BASE Show details 12 [18F]AV-1451 tau-PET and primary progressive aphasia Josephs, Keith A.; Martin, Peter R.; Botha, Hugo. - 2018 BASE Show details 13 Tau Uptake in Agrammatic Primary Progressive Aphasia with and without Apraxia of Speech Utianski, Rene L.; Whitwell, Jennifer L.; Schwarz, Christopher G.. - 2018 BASE Show details 14 Disrupted functional connectivity in primary progressive apraxia of speech Botha, Hugo; Utianski, Rene L.; Whitwell, Jennifer L.. - : Elsevier, 2018 BASE Show details 15 Tau-PET imaging with [18F]AV-1451 in Primary Progressive Apraxia of Speech Utianski, Rene L.; Whitwell, Jennifer L.; Schwarz, Christopher G.. - 2018 BASE Show details 16 Prosodic and Phonetic Subtypes of Primary Progressive Apraxia of Speech Utianski, Rene L.; Duffy, Joseph R.; Clark, Heather M.. - 2018 BASE Show details 17 Predicting clinical decline in progressive agrammatic aphasia and apraxia of speech Whitwell, Jennifer L.; Weigand, Stephen D.; Duffy, Joseph R.. - : Lippincott Williams & Wilkins, 2017 BASE Show details 18 Varying degrees of temporoparietal hypometabolism on FDG-PET reveal amyloid-positive logopenic primary progressive aphasia is not a homogeneous clinical entity Krishnan, Kamini; Machulda, Mary M.; Whitwell, Jennifer L.. - 2017 BASE Show details 19 Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults Risacher, Shannon Leigh; McDonald, Brenna C.; Tallman, Eileen F.... In: PMC (2016) BASE Show details 20 Tracking the Development of Agrammatic Aphasia: a Tensor-Based Morphometry Study Whitwell, Jennifer L.; Duffy, Joseph R.; Machulda, Mary M.. - 2016 BASE Show details Page: 1 2 3

Mobile view All Catalogues UB Frankfurt Linguistik 0 IDS Mannheim 0 OLC Linguistik 2 UB Frankfurt Retrokatalog 0 DNB Subject Category Language 0 Institut für Empirische Sprachwissenschaft 0 Leibniz-Centre General Linguistics (ZAS) 0 Bibliographies BLLDB 1 BDSL 0 IDS Bibliografie zur deutschen Grammatik 0 IDS Bibliografie zur Gesprächsforschung 0 IDS Konnektoren im Deutschen 0 IDS Präpositionen im Deutschen 0 IDS OBELEX meta 0 MPI-SHH Linguistics Collection 0 MPI for Psycholinguistics 0 Linked Open Data catalogues Annohub 0 Online resources Link directory 0 Journal directory 0 Database directory 0 Dictionary directory 0 Open access documents BASE 39 Linguistik-Repository 0 IDS Publikationsserver 0 Online dissertations 0 Language Description Heritage 0