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Simple Search
Hits 1 – 16 of 16
1
Huli of Papua : A cognatic descent system
Glasse, Robert M.
[Verfasser];
Barnes, J. A.
[Herausgeber]. - Berlin/Boston : De Gruyter, 2018
DNB Subject Category Language
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2
Cytisine versus varenicline for smoking cessation in Māori (the indigenous people of New Zealand) and their extended family: Study protocol for a randomised, non-inferiority trial
Walker, N
;
Smith, B
;
Barnes, J
. - : Wiley, 2018
BASE
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3
Utilising Openair to support multi-stakeholder engagement and the resolution of air quality issues
Hayes, E. T.
;
Chatterton, T.
;
Barnes, J.
. - : National Association for Clean Air, 2013
BASE
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4
The health and development of children born to older mothers in the United Kingdom: observational study using longitudinal cohort data.
Sutcliffe, AG
;
Barnes, J
;
Belsky, J
...
In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (2012)
BASE
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5
The health and development of children born to older mothers in the United Kingdom: observational study using longitudinal cohort data
Sutcliffe, AG
;
Barnes, J
;
Belsky, J
...
In: British Medical Journal , 345 , Article e5116. (2012) (2012)
BASE
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6
Basic Visual Function and Cortical Thickness Patterns in Posterior Cortical Atrophy
Lehmann, M
;
Barnes, J
;
Ridgway, GR
...
In: CEREB CORTEX , 21 (9) 2122 - 2132. (2011) (2011)
BASE
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7
Effects of early child-care on cognition, language, and task-related behaviours at 18 months: an English study.
Sylva, K
;
Stein, A
;
Leach, P
...
In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Web of Science (Lite) (http://apps.webofknowledge.com/summary.do) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (2011)
BASE
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8
Reduced Cortical Thickness in the Posterior Cingulate Gyrus is Characteristic of Both Typical and Atypical Alzheimer's Disease
Lehmann, M
;
Rohrer, JD
;
Clarkson, MJ
;
Ridgway, GR
;
Scahill, RI
;
Modat, M
;
Warren, JD
;
Ourselin, S
;
Barnes, J
;
Rossor, MN
;
Fox, NC
In: J ALZHEIMERS DIS , 20 (2) 587 - 598. (2010) (2010)
Abstract:
Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD) can be difficult to differentiate clinically due to overlapping symptoms. Subject classification in research studies is often based on clinical rather than pathological criteria which may mean some subjects are misdiagnosed and misclassified. Recently, methods measuring cortical thickness using magnetic resonance imaging have been suggested to be effective in differentiating between clinically-defined AD and frontotemporal dementia (FTD) in addition to showing disease-related patterns of atrophy. In this study we used FreeSurfer, a freely-available and automated software tool, to measure cortical thickness in 28 pathologically-confirmed AD patients, of which 11 had a typical amnestic presentation and 17 an atypical presentation during life, 23 pathologically-confirmed FTLD subjects, and 25 healthy controls. Patients with AD pathology, irrespective of clinical diagnosis, showed reduced cortical thickness bilaterally in the medial temporal lobe, posterior cingulate gyrus, precuneus, posterior parietal lobe, and frontal pole compared with controls. We further showed that lower cortical thickness in the posterior cingulate gyrus, parietal lobe, and frontal pole is suggestive of AD pathology in patients with behavioral or language deficits. In contrast, lower cortical thickness in the anterior temporal lobe and frontal lobe is indicative of the presence of FTLD pathology in patients with a clinical presentation of FTD. Reduced cortical thickness in the posterior cingulate gyrus is characteristic of AD pathology in patients with typical and atypical clinical presentations of AD, and may assist a clinical distinction of AD pathology from FTLD pathology.
Keyword:
Alzheimer's disease
;
ATROPHY
;
cortical thickness
;
DIAGNOSIS
;
FreeSurfer
;
FRONTAL-VARIANT
;
FRONTOTEMPORAL LOBAR DEGENERATION
;
magnetic resonance imaging
;
MRI
;
pathology
;
PATTERNS
;
PRIMARY PROGRESSIVE APHASIA
;
SEMANTIC DEMENTIA
;
TEMPORAL-LOBE
;
VOXEL-BASED MORPHOMETRY
URL:
http://discovery.ucl.ac.uk/144922/1/144922.pdf
http://discovery.ucl.ac.uk/144922/
BASE
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9
Cheminformatics Analysis of Assertions Mined from Literature that Describe Drug-Induced Liver Injury in Different Species
Fourches, D.
;
Barnes, J. C.
;
Day, N. C.
. - 2010
BASE
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10
Tracking progression in frontotemporal lobar degeneration Serial MRI in semantic dementia
Rohrer, JD
;
McNaught, E
;
Foster, J
...
In: NEUROLOGY , 71 (18) 1445 - 1451. (2008) (2008)
BASE
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11
Mapping the progression of progranulin-associated frontotemporal lobar degeneration
Rohrer, JD
;
Warren, JD
;
Barnes, J
...
In: NAT CLIN PRACT NEURO , 4 (8) 455 - 460. (2008) (2008)
BASE
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12
Effects of fully-established Sure Start Local Programmes on 3-year-old children and their families living in England: a quasi-experimental observational study
Melhuish, E.
;
Belsky, J.
;
Leyland, A.H.
. - 2008
BASE
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13
Effects of fully-established Sure Start Local Programmes on 3-year-old children and their families living in England: a quasi-experimental observational study.
Melhuish, E
;
Belsky, J
;
Leyland, AH
...
In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (2008)
BASE
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14
The influence of maternal depression, caregiving, and socioeconomic status in the post-natal year on children's language development.
Leach, P
;
Barnes, J
;
Malmberg, LE
...
In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Web of Science (Lite) (http://apps.webofknowledge.com/summary.do) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (2008)
BASE
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15
Effects of Sure Start local programmes on children and families: early findings from a quasi-experimental, cross sectional study.
Belsky, J
;
Melhuish, E
;
Barnes, J
...
In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (2006)
BASE
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16
The other side of the ecotourism coin: consumptive tourism in Southern Africa
Novelli, Marina
;
Barnes, J.
;
Humavindu, M.
. - 2006
BASE
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