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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 10 of 10 1 Neural Decoding Reveals Concurrent Phonemic and Subphonemic Representations of Speech Across Tasks Beach, Sara Dawley; Ozernov-Palchik, Ola; May, Sidney C... In: MIT Press (2021) BASE Show details 2 Disrupted left fusiform response to print in beginning kindergartners is associated with subsequent reading Centanni, Tracy M; Norton, Elizabeth; Ozernov-Palchik, Ola... In: Elsevier (2019) BASE Show details 3 Knockdown of Dyslexia-Gene Dcdc2 Interferes with Speech Sound Discrimination in Continuous Streams Booker, A. B.; Chen, F.; Sloan, A. M.... In: Society for Neuroscience (2016) BASE Show details 4 The Role of Candidate-Gene CNTNAP2 in Childhood Apraxia of Speech and Specific Language Impairment Centanni, Tracy M.; Sanmann, J. N.; Green, J. R.... In: Speech Pathology and Audiology Faculty Research and Publications (2015) BASE Show details 5 Degraded neural and behavioral processing of speech sounds in a rat model of Rett syndrome Engineer, Crystal T.; Rahebi, Kimiya C.; Borland, Michael S.; Buell, Elizabeth P.; Centanni, Tracy M.; Fink, Melyssa K.; Im, Kwok W.; Wilson, Linda G.; Kilgard, Michael P.. - 2015 Abstract: Individuals with Rett syndrome have greatly impaired speech and language abilities. Auditory brainstem responses to sounds are normal, but cortical responses are highly abnormal. In this study, we used the novel rat Mecp2 knockout model of Rett syndrome to document the neural and behavioral processing of speech sounds. We hypothesized that both speech discrimination ability and the neural response to speech sounds would be impaired in Mecp2 rats. We expected that extensive speech training would improve speech discrimination ability and the cortical response to speech sounds. Our results reveal that speech responses across all four auditory cortex fields of Mecp2 rats were hyperexcitable, responded slower, and were less able to follow rapidly presented sounds. While Mecp2 rats could accurately perform consonant and vowel discrimination tasks in quiet, they were significantly impaired at speech sound discrimination in background noise. Extensive speech training improved discrimination ability. Training shifted cortical responses in both Mecp2 and control rats to favor the onset of speech sounds. While training increased the response to low frequency sounds in control rats, the opposite occurred in Mecp2 rats. Although neural coding and plasticity are abnormal in the rat model of Rett syndrome, extensive therapy appears to be effective. These findings may help to explain some aspects of communication deficits in Rett syndrome and suggest that extensive rehabilitation therapy might prove beneficial. Keyword: Article URL: https://doi.org/10.1016/j.nbd.2015.08.019 http://www.ncbi.nlm.nih.gov/pubmed/26321676 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674323/ BASE Hide details 6 Speech sound discrimination training improves auditory cortex responses in a rat model of autism Engineer, Crystal T.; Centanni, Tracy M.; Im, Kwok W.. - : Frontiers Media S.A., 2014 BASE Show details 7 Speech Sound Processing Deficits and Training-Induced Neural Plasticity in Rats with Dyslexia Gene Knockdown Centanni, Tracy M.; Chen, Fuyi; Booker, Anne M.. - : Public Library of Science, 2014 BASE Show details 8 Phonological and lexical influences on phonological awareness in children with specific language impairment and dyslexia Farquharson, Kelly; Centanni, Tracy M.; Franzluebbers, Chelsea E.. - : Frontiers Media S.A., 2014 BASE Show details 9 Degraded speech sound processing in a rat model of fragile X syndrome Engineer, Crystal T.; Centanni, Tracy M.; Im, Kwok W.. - 2014 BASE Show details 10 Phonological and lexical influences on phonological awareness in children with specific language impairment and dyslexia Farquharson, Kelly; Centanni, Tracy M.; Franzluebbers, Chelsea E.... In: Special Education and Communication Disorders Faculty Publications (2014) BASE Show details

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