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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 Hits 1 – 20 of 35 1 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans Sønderby, Ida E.; van der Meer, Dennis; Moreau, Clara. - : Springer Nature, 2021 BASE Show details 2 Spatially resolved estimation of metabolic oxygen consumption from optical measurements in cortex Sætra, Marte J.; Solbrå, Andreas V.; Devor, Anna... In: Neurophotonics (2020) BASE Show details 3 Enrichment of genetic markers of recent human evolution in educational and cognitive traits. Srinivasan, Saurabh; Bettella, Francesco; Frei, Oleksandr... In: Scientific reports, vol 8, iss 1 (2018) BASE Show details 4 Enrichment of genetic markers of recent human evolution in educational and cognitive traits Srinivasan, Saurabh; Bettella, Francesco; Frei, Oleksandr. - : Nature Publishing Group UK, 2018 BASE Show details 5 Novel genetic loci associated with hippocampal volume Hibar, Derrek P.; Adams, Hieab H. H.; Jahanshad, Neda... In: ISSN: 2041-1723 ; EISSN: 2041-1723 ; Nature Communications ; https://hal.archives-ouvertes.fr/hal-01488337 ; Nature Communications, Nature Publishing Group, 2017, 8, pp.13624. ⟨10.1038/ncomms13624⟩ (2017) BASE Show details 6 Novel genetic loci underlying human intracranial volume identified through genome-wide association Adams, Hieab H H; Hibar, Derrek P; Chouraki, Vincent... In: ISSN: 1097-6256 ; EISSN: 1546-1726 ; Nature Neuroscience ; https://hal.archives-ouvertes.fr/hal-01382716 ; Nature Neuroscience, Nature Publishing Group, 2016, 19 (12), pp.1569-1582. ⟨10.1038/nn.4398⟩ (2016) BASE Show details 7 A human neurodevelopmental model for Williams syndrome. Chailangkarn, Thanathom; Trujillo, Cleber A; Freitas, Beatriz C... In: Nature, vol 536, iss 7616 (2016) BASE Show details 8 A human neurodevelopmental model for Williams syndrome. Chailangkarn, Thanathom; Trujillo, Cleber A; Freitas, Beatriz C... In: Nature, vol 536, iss 7616 (2016) BASE Show details 9 Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children. Eicher, John D; Montgomery, Angela M; Akshoomoff, Natacha... In: Brain imaging and behavior, vol 10, iss 1 (2016) BASE Show details 10 Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children. Eicher, John D; Montgomery, Angela M; Akshoomoff, Natacha; Amaral, David G; Bloss, Cinnamon S; Libiger, Ondrej; Schork, Nicholas J; Darst, Burcu F; Casey, BJ; Chang, Linda; Ernst, Thomas; Frazier, Jean; Kaufmann, Walter E; Keating, Brian; Kenet, Tal; Kennedy, David; Mostofsky, Stewart; Murray, Sarah S; Sowell, Elizabeth R; Bartsch, Hauke; Kuperman, Joshua M; Brown, Timothy T; Hagler, Donald J; Dale, Anders M; Jernigan, Terry L; Gruen, Jeffrey R; Pediatric Imaging Neurocognition Genetics Study In: Brain imaging and behavior, vol 10, iss 1 (2016) Abstract: Dyslexia and language impairment (LI) are complex traits with substantial genetic components. We recently completed an association scan of the DYX2 locus, where we observed associations of markers in DCDC2, KIAA0319, ACOT13, and FAM65B with reading-, language-, and IQ-related traits. Additionally, the effects of reading-associated DYX3 markers were recently characterized using structural neuroimaging techniques. Here, we assessed the neuroimaging implications of associated DYX2 and DYX3 markers, using cortical volume, cortical thickness, and fractional anisotropy. To accomplish this, we examined eight DYX2 and three DYX3 markers in 332 subjects in the Pediatrics Imaging Neurocognition Genetics study. Imaging-genetic associations were examined by multiple linear regression, testing for influence of genotype on neuroimaging. Markers in DYX2 genes KIAA0319 and FAM65B were associated with cortical thickness in the left orbitofrontal region and global fractional anisotropy, respectively. KIAA0319 and ACOT13 were suggestively associated with overall fractional anisotropy and left pars opercularis cortical thickness, respectively. DYX3 markers showed suggestive associations with cortical thickness and volume measures in temporal regions. Notably, we did not replicate association of DYX3 markers with hippocampal measures. In summary, we performed a neuroimaging follow-up of reading-, language-, and IQ-associated DYX2 and DYX3 markers. DYX2 associations with cortical thickness may reflect variations in their role in neuronal migration. Furthermore, our findings complement gene expression and imaging studies implicating DYX3 markers in temporal regions. These studies offer insight into where and how DYX2 and DYX3 risk variants may influence neuroimaging traits. Future studies should further connect the pathways to risk variants associated with neuroimaging/neurocognitive outcomes. Keyword: 2.1 Biological and endogenous factors; Adolescent; Basic Behavioral and Social Science; Behavioral and Social Science; Brain; Brain Disorders; Cell Adhesion Molecules; Child; Clinical Research; Cohort Studies; Cross-Sectional Studies; Diffusion Magnetic Resonance Imaging; Diffusion Tensor Imaging; Dyslexia; DYX2; DYX3; Experimental Psychology; Genetic Predisposition to Disease; Genetics; Genotyping Techniques; Humans; Imaging-genetics; KIAA0319; Language Development Disorders; Language impairment; Medical and Health Sciences; Mental health; Nerve Tissue Proteins; Neurosciences; Organ Size; Pediatric; Pediatric Imaging Neurocognition Genetics Study; Polymorphism; Preschool; Prevention; Proteins; Psychology and Cognitive Sciences; Single Nucleotide; Thiolester Hydrolases; White Matter; Young Adult URL: https://escholarship.org/uc/item/7rh1571s BASE Hide details 11 Common genetic variants influence human subcortical brain structures. Hibar, Derrek P; Stein, Jason L; Renteria, Miguel E... In: ISSN: 0028-0836 ; EISSN: 1476-4679 ; Nature ; https://hal.archives-ouvertes.fr/hal-01196805 ; Nature, Nature Publishing Group, 2015, 520 (7546), pp.224-9. ⟨10.1038/nature14101⟩ (2015) BASE Show details 12 Atypical right hemisphere specialization for object representations in an adolescent with specific language impairment. Brown, Timothy T; Erhart, Matthew; Avesar, Daniel... In: Frontiers in human neuroscience, vol 8, iss 1 FEB (2014) BASE Show details 13 Atypical Right Hemisphere Specialization for Object Representations in an Adolescent with Specific Language Impairment Brown, Timothy T.; Erhart, Matthew; Avesar, Daniel. - : Frontiers Media S.A., 2014 BASE Show details 14 Age-related Changes in Tissue Signal Properties Within Cortical Areas Important for Word Understanding in 12- to 19-Month-Old Infants Travis, Katherine E.; Curran, Megan M.; Torres, Christina. - : Oxford University Press, 2013 BASE Show details 15 Independence of Early Speech Processing from Word Meaning Travis, Katherine E.; Leonard, Matthew K.; Chan, Alexander M.. - : Oxford University Press, 2013 BASE Show details 16 Independence of Early Speech Processing from Word Meaning Travis, Katherine E.; Leonard, Matthew K.; Chan, Alexander M.. - : Oxford University Press, 2012 BASE Show details 17 Age-related changes in the neurophysiology of language in adults: Relationship to regional cortical thinning and white matter microstructure Kemmotsu, Nobuko; Girard, Holly M.; Kucukboyaci, N. Erkut. - 2012 BASE Show details 18 Language proficiency modulates the recruitment of non-classical language areas in bilinguals. Leonard, Matthew K; Torres, Christina; Travis, Katherine E... In: PloS one, vol 6, iss 3 (2011) BASE Show details 19 Right hemisphere has the last laugh: neural dynamics of joke appreciation. Marinkovic, Ksenija; Baldwin, Sharelle; Courtney, Maureen G... In: Cognitive, affective & behavioral neuroscience, vol 11, iss 1 (2011) BASE Show details 20 Spatiotemporal Neural Dynamics of Word Understanding in 12- to 18-Month-Old-Infants Travis, Katherine E.; Leonard, Matthew K.; Brown, Timothy T.. - : Oxford University Press, 2011 BASE Show details Page: 1 2

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