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Selective impairment of action-verb naming and comprehension in progressive supranuclear palsy
Daniele, Antonio (orcid:0000-0003-1641-5852); Barbier, Annalisa; Di Giuda, Daniela (orcid:0000-0002-5758-3986). - : Elsevier Ltd, 2013
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2
Selective impairment of action-verb naming and comprehension in progressive supranuclear palsy
Daniele, Antonio (orcid:0000-0003-1641-5852); Barbier, Annalisa; Di Giuda, Daniela (orcid:0000-0002-5758-3986). - 2012
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3
Effects of stimulation of the subthalamic nucleus on naming and reading nouns and verbs in Parkinson's disease
Silveri, Maria Caterina (orcid:0000-0001-5012-0682); Ciccarelli, Nicoletta (orcid:0000-0002-7582-9142); Baldonero, Eleonora; Piano, Carla; Zinno, Massimiliano; Soleti, Francesco; Bentivoglio, Anna Rita (orcid:0000-0002-9663-095X); Albanese, Alberto (orcid:0000-0002-5864-0006); Daniele, Antonio (orcid:0000-0003-1641-5852). - : Elsevier Science Limited, 2012
Abstract: An impairment for verbs has been described in patients with Parkinson's disease (PD), suggesting that a disruption of frontal-subcortical circuits may result in dysfunction of the neural systems involved in action-verb processing. A previous study suggested that deep brain stimulation (DBS) of the subthalamic nucleus (STN) during verb generation may affect the ability to select from many competing lexical alternatives. In this study, 12 PD patients who had undergone bilateral STN DBS and completed an 8-year follow-up and 14 matched normal controls were administered action and object naming tasks and verb and noun reading tasks. Their responses were recorded using a microphone, resulting in a signal that marked the onset of the verbal response and allowed to measure response times (RTs). Accuracy was scored manually. RESULTS: Overall performance in naming (independently of stimulation): In naming task controls were faster and more accurate than PD patients. In both groups, performance (accuracy and RTs) was worse on action naming than object naming. PD patients were significantly slower than controls in naming actions. Effect of stimulation: Compared with the OFF stimulation condition, in ON stimulation condition PD patients showed improved performance on object and action naming tasks (increased accuracy, faster RTs), with a decreased number of semantic errors. Some evidence also emerged that action naming in the ON stimulation condition improved more than object naming. On noun and verb reading tasks, although accuracy was at ceiling in both groups and no significant difference was observed in RTs for nouns and verbs, PD patients were slower than controls. CONCLUSIONS: Our findings suggest that STN DBS may improve lexical search in PD patients. We hypothesize that STN stimulation may facilitate the motor components involved in naming and reading tasks (increased speed of speech onset), resulting in shorter RTs in both naming and reading and, to some extent, in increased accuracy in naming due to fewer omissions (no response within the 7500ms time limit). However, to account for greater accuracy in naming due to decreased number of semantic errors in the ON stimulation condition, we hypothesize that STN stimulation restores the activity of the corticostriatal circuits involved in selection processes of a target word among different alternatives.
Keyword: parkinson disease; Settore MED/26 - NEUROLOGIA
URL: https://doi.org/10.1016/j.neuropsychologia.2012.04.023
http://hdl.handle.net/10807/26510
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4
Selective impairment of action-verb naming and comprehension in progressive supranuclear palsy
Daniele, Antonio (orcid:0000-0003-1641-5852); Barbier, Annalisa; Di Giuda, Daniela (orcid:0000-0002-5758-3986). - : Masson SPA, 2012
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5
TOMM40, APOE, and APOC1 in Primary Progressive Aphasia and Frontotemporal Dementia
Seripa, D; Bizzarro, Alessandra; Pilotto, A. - : IOS Press, 2012
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6
FOXP2, APOE, and PRNP: New Modulators in Primary Progressive Aphasia
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7
Melchiorre Cesarotti
Daniele, Antonio (Hrsg.). - Padova : Esedra Ed., 2011
BLLDB
UB Frankfurt Linguistik
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8
Teoria e prassi della traduzione : atti del convegno di Udine, 29 - 30 maggio 2007
Daniele, Antonio (Hrsg.). - Padova : Esedra, 2009
UB Frankfurt Linguistik
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9
APOE epsilon 2/epsilon 4 genotype a risk factor for primary progressive aphasia in women
Daniele, Antonio (orcid:0000-0003-1641-5852); Matera, Mg; Seripa, D. - 2009
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10
Lexikologie : ein internationales Handbuch zur Natur und Struktur von Wörtern und Wortschätzen 2. 2
In: 2 (2005), S. 1757-1772
Leibniz-Zentrum Allgemeine Sprachwissenschaft
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11
L' italiano e le regioni : Atti del Convegno di Studi Udine, 15-16 giugno 2001
Fusco, Fabiana (Hrsg.); Marcato, Carla (Hrsg.); Grassi, Corrado (Mitarb.)...
In: Plurilinguismo. - Udine : Forum Ed. Univ. Udinese SrL 8 (2001), 7-238
BLLDB
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12
Selective deficit for people's names following left temporal damage : an impairment of domain-specific conceptual knowledge
In: Cognitive neuropsychology. - Abingdon : Routledge, Taylor & Francis Group 17 (2000) 6, 489-516
BLLDB
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13
SELECTIVE DEFICIT FOR PEOPLE'S NAMES FOLLOWING LEFT TEMPORAL DAMAGE: AN IMPAIRMENT OF DOMAIN-SPECIFIC CONCEPTUAL KNOWLEDGE
In: Cognitive neuropsychology. - Abingdon : Routledge, Taylor & Francis Group 17 (2000) 6, 489-516
OLC Linguistik
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14
Neuroanatomical correlates of category-specific semantic disorders : a critical survey
In: Semantic knowledge and semantic representations (Hove, 1995), p. 247-264
MPI für Psycholinguistik
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15
Neuroanatomical Correlates of Category-specific Semantic Disorders: A Critical Survey
Gainotti, Guido; Silveri, Maria Caterina (orcid:0000-0001-5012-0682); Daniele, Antonio (orcid:0000-0003-1641-5852). - 1995
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16
Can residual lexical knowledge concern word form rather than word meaning?
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 43 (1992) 4, 597-612
BLLDB
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17
Autonomic reactivity and facial expression of emotion in brain-damaged patients
In: Emotions and the dual brain (London [etc.], 1989), P.204-222
MPI für Psycholinguistik
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18
Scritti di filologia e linguistica
Mussafia, Adolfo; Daniele, Antonio. - Padova : Ed. Antenore, 1983
Leibniz-Zentrum Allgemeine Sprachwissenschaft
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19
La metafora politica nel romanzo 'I vecchi e i giovani' di Luigi Pirandello
In: Circolo Filologico-Linguistico Padovano. Quaderni del Circolo Filologico-Linguistico Padovano. - Padova : Esedra Ed. (1977) 9, 161-176
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