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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 Hits 1 – 20 of 47 1 In Search of Cognitive Promotive and Protective Factors for Word Reading Slomowitz, Rebecca F.; Narayan, Angela J.; Pennington, Bruce F.... In: Sci Stud Read (2020) BASE Show details 2 Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia ... Gialluisi, Alessandro; Andlauer, Till F.M.; Mirza-Schreiber, Nazanin. - : ETH Zurich, 2019 BASE Show details 3 Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia Gialluisi, Alessandro; Andlauer, Till F.M.; Mirza-Schreiber, Nazanin... In: Translational Psychiatry, 9 (1) (2019) BASE Show details 4 Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia Gialluisi, Alessandro; Andlauer, Till F. M.; Mirza-schreiber, Nazanin; Moll, Kristina; Becker, Jessica; Hoffmann, Per; Ludwig, Kerstin U.; Czamara, Darina; St Pourcain, Beate; Brandler, William; Honbolygó, Ferenc; Tóth, Dénes; Csépe, Valéria; Huguet, Guillaume; Morris, Andrew P.; Hulslander, Jacqueline; Willcutt, Erik G.; Defries, John C.; Olson, Richard K.; Smith, Shelley D.; Pennington, Bruce F.; Vaessen, Anniek; Maurer, Urs; Lyytinen, Heikki; Peyrard-janvid, Myriam; Leppänen, Paavo H. T.; Brandeis, Daniel; Bonte, Milene; Stein, John F.; Talcott, Joel B.; Fauchereau, Fabien; Wilcke, Arndt; Francks, Clyde; Bourgeron, Thomas; Monaco, Anthony P.; Ramus, Franck; Landerl, Karin; Kere, Juha; Scerri, Thomas S.; Paracchini, Silvia; Fisher, Simon E.; Schumacher, Johannes; Nöthen, Markus M.; Müller-myhsok, Bertram; Schulte-körne, Gerd. - 2019 Abstract: A.G. and T.F.M.A. were supported by the Munich Cluster for Systems Neurology (SyNergy). S.P. is a Royal Society University research Fellow. B.M.M., C.F., B.S.P., and S.E.F. are supported by the Max Planck Society. A.P.M. is a Wellcome Senior Fellow in Basic Biomedical Science (WT098017). F.R. is supported by Agence Nationale de la Recherche (ANR-06-NEURO-019-01, ANR-10-LABX-0087 IEC, ANR-10-IDEX-0001-02 PSL, ANR-11-BSV4-014-01), European Commission (LSHM-CT-2005-018696), Ville de Paris. ; Developmental dyslexia (DD) is one of the most prevalent learning disorders, with high impact on school and psychosocial development and high comorbidity with conditions like attention-deficit hyperactivity disorder (ADHD), depression, and anxiety. DD is characterized by deficits in different cognitive skills, including word reading, spelling, rapid naming, and phonology. To investigate the genetic basis of DD, we conducted a genome-wide association study (GWAS) of these skills within one of the largest studies available, including nine cohorts of reading-impaired and typically developing children of European ancestry (N = 2562–3468). We observed a genome-wide significant effect (p < 1 × 10−8) on rapid automatized naming of letters (RANlet) for variants on 18q12.2, within MIR924HG (micro-RNA 924 host gene; rs17663182 p = 4.73 × 10−9), and a suggestive association on 8q12.3 within NKAIN3 (encoding a cation transporter; rs16928927, p = 2.25 × 10−8). rs17663182 (18q12.2) also showed genome-wide significant multivariate associations with RAN measures (p = 1.15 × 10−8) and with all the cognitive traits tested (p = 3.07 × 10−8), suggesting (relational) pleiotropic effects of this variant. A polygenic risk score (PRS) analysis revealed significant genetic overlaps of some of the DD-related traits with educational attainment (EDUyears) and ADHD. Reading and spelling abilities were positively associated with EDUyears (p ~ [10−5–10−7]) and negatively associated with ADHD PRS (p ~ [10−8−10−17]). This corroborates a long-standing hypothesis on the partly shared genetic etiology of DD and ADHD, at the genome-wide level. Our findings suggest new candidate DD susceptibility genes and provide new insights into the genetics of dyslexia and its comorbities. ; Publisher PDF ; Peer reviewed Keyword: BDC; DAS; QH301; QH301 Biology; R2C; RC0321; RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry; RJ; RJ Pediatrics; ~DC~ URL: https://doi.org/10.1038/s41398-019-0402-0 http://hdl.handle.net/10023/17043 https://www.biorxiv.org/content/early/2018/05/02/309336 BASE Hide details 5 Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia Gialluisi, Alessandro; Andlauer, Till F. M.; Mirza-schreiber, Nazanin. - 2019 BASE Show details 6 Examining the Influence of Perceived Stress on Developmental Change in Memory and Perceptual Speed for Adopted and Non-Adopted Individuals Ricker, Ashley A.; Corley, Robin; DeFries, John C.. - 2017 BASE Show details 7 Genome-wide screening for DNA variants associated with reading and language traits Gialluisi, Alessandro; Newbury, Dianne F; Wilcutt, Erik G. - 2015 BASE Show details 8 Characterization of the DYX2 locus on chromosome 6p22 with reading disability, language impairment, and IQ Eicher, John D.; Powers, Natalie R.; Miller, Laura L.. - : Springer Berlin Heidelberg, 2014 BASE Show details 9 Genetic and Environmental Etiologies of the Longitudinal Relations between Pre-reading Skills and Reading Christopher, Micaela E.; Hulslander, Jacqueline; Byrne, Brian. - 2014 BASE Show details 10 Genetic and environmental influences on writing and their relations to language and reading Olson, Richard K.; Hulslander, Jacqueline; Christopher, Micaela... In: Annals of dyslexia. - New York, NY : Springer 63 (2013) 1, 25-43 OLC Linguistik Show details 11 DNA Evidence for Strong Genome-Wide Pleiotropy of Cognitive and Learning Abilities Trzaskowski, Maciej; Davis, Oliver S. P.; DeFries, John C.. - : Springer US, 2013 BASE Show details 12 A multivariate twin study of early literacy in Japanese Kana Fujisawa, Keiko K.; Wadsworth, Sally J.; Kakihana, Shinichiro. - 2013 BASE Show details 13 DNA evidence for strong genome-wide pleiotropy of cognitive and learning abilities Trzaskowski, Maciej; Davis, Oliver S. P.; DeFries, John C.. - : Springer, 2013 BASE Show details 14 Predicting Word Reading and Comprehension with Executive Function and Speed Measures Across Development: A Latent Variable Analysis Christopher, Micaela E.; Miyake, Akira; Keenan, Janice M.. - 2012 BASE Show details 15 Choice of Reading Comprehension Test Influences the Outcomes of Genetic Analyses Betjemann, Rebecca S.; Keenan, Janice M.; Olson, Richard K.. - 2011 BASE Show details 16 Genetic and environmental influences on aspects of literacy and language in early childhood: Continuity and change from preschool to Grade 2 Byrne, Brian; Coventry, William L.; Olson, Richard K.... In: Journal of neurolinguistics. - Orlando, Fla. : Elsevier 22 (2009) 3, 219-236 OLC Linguistik Show details 17 Genetic and environmental influences on aspects of literacy and language in early childhood: continuity and change from preschool to grade 2 Byrne, Brian; Coventry, William L.; Olson, Richard K.... In: Journal of neurolinguistics. - Orlando, Fla. : Elsevier 22 (2009) 3, 219-236 BLLDB Show details 18 Gender ratios for reading difficulties DeFries, John C.; Olson, Richard K.; Hawke, Jesse L.... In: Dyslexia. - Bracknell : British Dyslexia Association 15 (2009) 3, 239-242 BLLDB OLC Linguistik Show details 19 Gene X Environment interactions in reading disability and attention-deficit/hyperactivity disorder Pennington, Bruce F.; McGrath, Lauren; Rosenberg, Jenni... In: Developmental psychology. - Richmond, Va. [u.a.] : American Psychological Association 45 (2009) 1, 77-89 BLLDB Show details 20 A behaviour-genetic analysis of orthographic learning, spelling and decoding Samuelsson, Stefan; Willcutt, Erik G.; Coventry, William L.... In: Journal of research in reading. - Leeds : Wiley-Blackwell 31 (2008) 1, 8-21 BLLDB OLC Linguistik Show details Page: 1 2 3

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