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1
Protocol for the development of the international population registry for aphasia after stroke (I-PRAISE)
In: Research outputs 2014 to 2021 (2022)
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2
Protocol for the development of the international population registry for aphasia after stroke (I-PRAISE)
Ali, M.; Ben Basat, A. L.; Berthier, M.. - : Informa UK Limited, 2021
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3
Caudate Nucleus Volumes in Frontotemporal Lobar Degeneration: Differential Atrophy in Subtypes
In: American Journal of Neuroradiology (2015)
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4
Cortical Morphometric Subclassification of Frontotemporal Lobar Degeneration
In: American Journal of Neuroradiology (2015)
Abstract: BACKGROUND AND PURPOSE: Frontotemporal lobar degeneration (FTLD) is a primary neurodegenerative disease comprising 3 clinical subtypes: frontotemporal dementia (FTD), semantic dementia (SD), and progressive nonfluent aphasia (PNFA). The subdivision is primarily based on the characteristic clinical symptoms displayed by each subtype. We hypothesized that these symptoms would be correlated to characteristic patterns of brain atrophy, which could be indentified and used for subclassification of subjects with FTLD. MATERIALS AND METHODS: Volumes of 9 cortical regions were manually parcellated and measured on both hemispheres on 27 controls, 12 patients with FTD, 9 patients with PNFA, and 13 patients with SD. The volumetric data were analyzed by traditional t tests and by a multivariate discriminant analysis (partial least squares discriminant analysis). RESULTS: The ensemble or pattern of atrophy was a good discriminator in pair-wise comparison between the subtypes: FTD compared with SD (sensitivity 100% [12/12], specificity 100% [13/13]); FTD compared with PNFA (sensitivity 92% [11/12], specificity 89% [8/9]); and SD compared with PNFA (sensitivity 86% [11/13], specificity 100% [9/9]). Temporal-versus-frontal atrophy was the most important pattern for discriminating SD from the other 2 subtypes. Right-sided versus left-sided atrophy was the most important pattern for discriminating between subjects with FTD and PNFA. CONCLUSIONS: FTLD subtypes generally display a characteristic pattern of atrophy, which may be considered in diagnosing patients with FTLD.
Keyword: aged; article; brain atrophy; brain cortex; brain size; clinical article; controlled study; diagnostic accuracy; discriminant analysis; disease classification; disease duration; female; frontotemporal dementia; human; image analysis; Keywords: adult; male; mini men
URL: http://hdl.handle.net/1885/35683
https://doi.org/10.3174/ajnr.A1545
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5
Cortical Morphometric Subclassification of Frontotemporal Lobar Degeneration
In: American Journal of Neuroradiology (2015)
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6
Shape analysis of the corpus callosum in Alzheimer's disease and frontotemporal lobar degeneration subtypes
In: Journal of Alzheimer's Disease (2015)
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7
Shape analysis of the corpus callosum in Alzheimer's disease and frontotemporal lobar degeneration subtypes
In: Journal of Alzheimer's Disease (2015)
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8
Putaminal Volume in Frontotemporal Lobar Degeneration and Alzheimer Disease: Differential Volumes in Dementia Subtypes and Controls
In: American Journal of Neuroradiology (2015)
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9
Putaminal Volume in Frontotemporal Lobar Degeneration and Alzheimer Disease: Differential Volumes in Dementia Subtypes and Controls
In: American Journal of Neuroradiology (2015)
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10
Caudate Nucleus Volumes in Frontotemporal Lobar Degeneration: Differential Atrophy in Subtypes
In: American Journal of Neuroradiology (2015)
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