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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 4 5 6 Hits 21 – 40 of 112 21 Abnormal Subcortical Components of the Corticostriatal System in Young Adults with DLI: A Combined Structural MRI and DTI Study Lee, Joanna C.; Nopoulos, Peggy C.; Tomblin, J. Bruce. - 2013 Abstract: Developmental Language Impairment (DLI) is a neurodevelopmental disorder affecting 12% to 14% of the school-age children in the United States. While substantial studies have shown a wide range of linguistic and non-linguistic difficulty in individuals with DLI, very little is known about the neuroanatomical mechanisms underlying this disorder. In the current study, we examined the subcortical components of the corticostriatal system in young adults with DLI, including the caudate nucleus, the putamen, the nucleus accumbens, the globus pallidus, and the thalamus. Additionally, the four cerebral lobes and the hippocampus were also comprised for an exploratory analysis. We used conventional magnetic resonance imaging (MRI) to measure regional brain volumes, as well as diffusion tensor imaging (DTI) to assess water diffusion anisotropy as quantified by fractional anisotropy (FA). Two groups of participants, one with DLI (n=12) and the other without ( n=12), were recruited from a prior behavioral study, and all were matched on age, gender, and handedness. Volumetric analyses revealed region-specific abnormalities in individuals with DLI, showing pathological enlargement bilaterally in the putamen and the nucleus accumbens, and unilaterally in the right globus pallidus after the intracranial volumes were controlled. Regarding the DTI findings, the DLI group showed decreased FA values in the globus pallidus and the thalamus but these significant differences disappeared after controlling for the whole-brain FA value, indicating that microstructural abnormality is diffuse and affects other regions of the brain. Taken together, these results suggest region-specific corticostriatal abnormalities in DLI at the macrostructural level, but corticostriatal abnormalities at the microstructural level may be a part of a diffuse pattern of brain development. Future work is suggested to investigate the relationship between corticostriatal connectivity and individual differences in language development. Keyword: Article URL: https://doi.org/10.1016/j.neuropsychologia.2013.07.011 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816105 http://www.ncbi.nlm.nih.gov/pubmed/23896446 BASE Hide details 22 Associations of Prenatal Nicotine Exposure and the Dopamine Related Genes ANKK1 and DRD2 to Verbal Language Eicher, John D.; Powers, Natalie R.; Cho, Kelly. - : Public Library of Science, 2013 BASE Show details 23 Growing Up With a Cochlear Implant: Education, Vocation, and Affiliation Spencer, Linda J.; Tomblin, J. Bruce; Gantz, Bruce J. In: Journal of deaf studies and deaf education. - Cary, NC : Oxford Univ. Press 17 (2012) 4, 483 OLC Linguistik Show details 24 Reinforcement learning in young adults with developmental language impairment Lee, Joanna C.; Tomblin, J. Bruce In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 123 (2012) 3, 154-163 BLLDB OLC Linguistik Show details 25 Exploring the comorbidity of attention-deficit, hyperactivity disorder and language, speech, and reading disorders Tomblin, J. Bruce (Hrsg.). - Hagerstown, Md. : Lippincott Williams & Wilkins, 2012 UB Frankfurt Linguistik Show details 26 The Aromatase Gene CYP19A1: Several Genetic and Functional Lines of Evidence Supporting a Role in Reading, Speech and Language Anthoni, Heidi; Sucheston, Lara E.; Lewis, Barbara A.. - : Springer US, 2012 BASE Show details 27 Grammar Predicts Procedural Learning and Consolidation Deficits in Children with Specific Language Impairment Hedenius, Martina; Persson, Jonas; Tremblay, Antoine. - 2011 BASE Show details 28 Electrophysiological correlates of rapid auditory and linguistic processing in adolescents with specific language impairment Leonard, Laurence B.; Weber-Fox, Christine M.; Wray, Amanda Hampton... In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 115 (2010) 3, 162-181 BLLDB OLC Linguistik Show details 29 Sequential expectations: the role of prediction-based learning in language Christiansen, Morten H.; Tomblin, J. Bruce; Misyak, Jennifer B. In: Topics in cognitive science. - Hoboken, NJ [u.a.] : Wiley 2 (2010) 1, 138-153 BLLDB OLC Linguistik Show details 30 Sequential Expectations: The Role of Prediction-Based Learning in Language Misyak, Jennifer B; Christiansen, Morten H; Tomblin, J Bruce In: Topics in cognitive science. - Hoboken, NJ [u.a.] : Wiley 2 (2010) 1, 138-153 OLC Linguistik Show details 31 Individual differences in online spoken word recognition: Implications for SLI McMurray, Bob; Samelson, Vicki M.; Lee, Sung Hee. - 2010 BASE Show details 32 On-Line Individual Differences in Statistical Learning Predict Language Processing Misyak, Jennifer B.; Christiansen, Morten H.; Tomblin, J. Bruce. - : Frontiers Research Foundation, 2010 BASE Show details 33 Electrophysiological Correlates of Rapid Auditory and Linguistic Processing in Adolescents with Specific Language Impairment Weber-Fox, Christine; Leonard, Laurence B.; Wray, Amanda Hampton. - 2010 BASE Show details 34 Sequential expectations : the role of prediction-based learning in language Misyak, Jennifer B.; Christiansen, Morten H.; Tomblin, J. Bruce. - : Wiley-Blackwell Publishing, Inc., 2010 BASE Show details 35 Language Features in a mother and daughter of a chromosome 7;13 translocation involving FOXP2 Tomblin, J. Bruce; Anderson, Steve; Patil, Shivanand... In: Journal of speech, language, and hearing research. - Rockville, Md. : American Speech-Language-Hearing Association 52 (2009) 5, 1157-1174 BLLDB OLC Linguistik Show details 36 The handbook of child language disorders Edwards, Jan; Fletcher, Paul; Hook, Pamela E.. - New York : Psychology Press, 2009 BLLDB UB Frankfurt Linguistik Show details 37 Childern with specific language impairment Tomblin, J. Bruce In: The Cambridge handbook of child language (Cambridge, 2009), p. 417-432 MPI für Psycholinguistik Show details 38 Children with specific language impairment Tomblin, J. Bruce In: The Cambridge handbook of child language. - Cambridge [u.a.] : Cambridge Univ. Press (2009), 417-431 BLLDB Show details 39 Seeing the world through a third eye: developmental systems theory looks beyond the nativist-empiricist debate : [authors' response] Spencer, John P.; Samuelson, Larissa K.; Blumberg, Mark S.... In: Child development perspectives. - Hoboken, NJ : Wiley 3 (2009) 2, 103-105 BLLDB Show details 40 Short arms and talking eggs: why we should no longer abide the nativist-empiricist debate : [main article] Spencer, John P.; Blumberg, Mark S.; McMurray, Bob... In: Child development perspectives. - Hoboken, NJ : Wiley 3 (2009) 2, 79-87 BLLDB Show details Page: 1 2 3 4 5 6

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