1 |
Investigating the effects of handedness on the consistency of lateralization for speech production and semantic processing tasks using functional transcranial Doppler sonography
|
|
|
|
BASE
|
|
Show details
|
|
2 |
Testing the unitary theory of language lateralization using functional transcranial Doppler sonography in adults
|
|
|
|
BASE
|
|
Show details
|
|
3 |
CATALISE : a multinational and multidisciplinary Delphi consensus study. Identifying language impairments in children
|
|
|
|
BASE
|
|
Show details
|
|
4 |
CATALISE : a multinational and multidisciplinary Delphi consensus study. Identifying language impairments in children
|
|
|
|
BASE
|
|
Show details
|
|
6 |
Increased prevalence of sex chromosome aneuploidies in specific language impairment and dyslexia
|
|
|
|
BASE
|
|
Show details
|
|
7 |
CNTNAP2 variants affect early language development in the general population
|
|
|
|
BASE
|
|
Show details
|
|
8 |
Overlaps between autism and language impairment: phenomimicry or shared etiology?
|
|
|
|
Abstract:
Traditionally, autistic spectrum disorder (ASD) and specific language impairment (SLI) are regarded as distinct conditions with separate etiologies. Yet these disorders co-occur at above chance levels, suggesting shared etiology. Simulations, however, show that additive pleiotropic genes cannot account for observed rates of language impairment in relatives, which are higher for probands with SLI than for those with ASD + language impairment. An alternative account is in terms of 'phenomimicry', i.e., language impairment in comorbid cases may be a consequence of ASD risk factors, and different from that seen in SLI. However, this cannot explain why molecular genetic studies have found a common risk genotype for ASD and SLI. This paper explores whether nonadditive genetic influences could account for both family and molecular findings. A modified simulation involving G x G interactions obtained levels of comorbidity and rates of impairment in relatives more consistent with observed values. The simulations further suggest that the shape of distributions of phenotypic trait scores for different genotypes may provide evidence of whether a gene is involved in epistasis. ; Citation: Bishop, D. V. M. (2010). 'Overlaps between autism and language impairment: phenomimicry or shared etiology?', Behavior Genetics 40(5), 618-629. [Available at http://www.springerlink.com/content/gg087q4h51j5127g/]. This article is distribured under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
|
|
Keyword:
autism; comorbidity; epistasis; Experimental psychology; specific language impairment
|
|
URL: http://www.springer.com/psychology/journal/10519 https://doi.org/10.1007/s10519-010-9381-x
|
|
BASE
|
|
Hide details
|
|
9 |
Lower-frequency event-related desynchronization: a signature of late mismatch responses to sounds, which is reduced or absent in children with specific language impairment
|
|
|
|
BASE
|
|
Show details
|
|
10 |
Genes, cognition, and communication: insights from neurodevelopmental disorders
|
|
|
|
BASE
|
|
Show details
|
|
13 |
Weak hand preference in children with down syndrome is associated with language deficits
|
|
|
|
BASE
|
|
Show details
|
|
14 |
Weak hand preference in children with Down syndrome is associated with language deficits
|
|
|
|
BASE
|
|
Show details
|
|
15 |
Heritability of specific language impairment depends on diagnostic criteria
|
|
|
|
BASE
|
|
Show details
|
|
16 |
Heritable risk factors associated with language impairments
|
|
|
|
BASE
|
|
Show details
|
|
17 |
Is poor frequency modulation detection linked to literacy problems? A comparison of specific reading disability and mild to moderate sensorineural hearing loss
|
|
|
|
BASE
|
|
Show details
|
|
18 |
Speech and non-speech processing in people with specific language impairment: a behavioural and electrophysiological study
|
|
|
|
BASE
|
|
Show details
|
|
19 |
Frequency discrimination deficits in people with specific language impairment : reliability, validity, and linguistic correlates
|
|
|
|
BASE
|
|
Show details
|
|
|
|