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Preoperative Assessment of Language Dominance through Combined Resting-State and Task-Based Functional Magnetic Resonance Imaging ...
Ott, Christian; Rosengarth, Katharina; Doenitz, Christian. - : Universität Regensburg, 2021
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Preoperative Assessment of Language Dominance through Combined Resting-State and Task-Based Functional Magnetic Resonance Imaging
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Assessing language dominance with functional MRI: The role of control tasks and statistical analysis ...
Abstract: There is a discrepancy between the brain regions revealed by functional neuroimaging techniques and those brain regions where a loss of function, either by lesion or by electrocortical stimulation, induces language disorders. To differentiate between essential and non-essential language-related processes, we investigated the effects of linguistic control tasks and different analysis methods for functional MRI data. Twelve subjects solved two linguistic generation tasks: (1) a verb generation task and (2) an antonym generation task (each with a linguistic control task on the phonological level) as well as two decision tasks of semantic congruency (each with a cognitive high-level control task). Differential contrasts and conjunction analyses were carried out on the single-subject level and an individual lateralization index (LI) was computed. On the group level we determined the percent signal change in the left inferior frontal gyrus (IFG: BA 44 and BA 45). The conjunction analysis of multiple language tasks ...
Keyword: 150 Psychologie; 570 Biowissenschaften, Biologie; Lateralization, Broca's, Presurgical, Semantic, Generation
URL: https://epub.uni-regensburg.de/id/eprint/41190
https://dx.doi.org/10.5283/epub.41190
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Assessing language dominance with functional MRI: The role of control tasks and statistical analysis
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