DE eng

Search in the Catalogues and Directories

Page: 1 2 3 4
Hits 1 – 20 of 70

1
What Language Disorders Reveal About the Mechanisms of Morphological Processing
In: Front Psychol (2021)
BASE
Show details
2
Thematic Integration Impairments in Primary Progressive Aphasia: Evidence From Eye-Tracking
In: Front Hum Neurosci (2021)
BASE
Show details
3
APOE is a correlate of phenotypic heterogeneity in Alzheimer disease in a national cohort
In: Neurology (2020)
BASE
Show details
4
Familial language network vulnerability in primary progressive aphasia
In: Neurology (2020)
BASE
Show details
5
Differential neurocognitive network perturbation in amnestic and aphasic Alzheimer disease
Martersteck, Adam; Sridhar, Jaiashre; Rader, Benjamin. - : Lippincott Williams & Wilkins, 2020
BASE
Show details
6
Perturbations of Language Network Connectivity in Primary Progressive Aphasia
In: Cortex (2019)
BASE
Show details
7
Word comprehension in temporal cortex and Wernicke area: A PPA perspective
Abstract: OBJECTIVE: To explore atrophy–deficit correlations of word comprehension and repetition in temporoparietal cortices encompassing the Wernicke area, based on patients with primary progressive aphasia (PPA). METHODS: Cortical thickness in regions within and outside the classical Wernicke area, measured by FreeSurfer, was correlated with repetition and single word comprehension scores in 73 right-handed patients at mild to moderate stages of PPA. RESULTS: Atrophy in the Wernicke area was correlated with repetition (r = 0.42, p = 0.001) but not single word comprehension (r = −0.072, p = 0.553). Correlations with word comprehension were confined to more anterior parts of the temporal lobe, especially its anterior third (r = 0.60, p < 0.001). A single case with postmortem autopsy illustrated preservation of word comprehension but not repetition 6 months prior to death despite nearly 50% loss of cortical volume and severe neurofibrillary degeneration in core components of the Wernicke area. CONCLUSIONS: Temporoparietal cortices containing the Wernicke area are critical for language repetition. Contrary to the formulations of classic aphasiology, their role in word and sentence comprehension is ancillary rather than critical. Thus, the Wernicke area is not sufficient to sustain word comprehension if the anterior temporal lobe is damaged. Traditional models of the role of the Wernicke area in comprehension are based almost entirely on patients with cerebrovascular lesions. Such lesions also cause deep white matter destruction and acute network diaschisis, whereas progressive neurodegenerative diseases associated with PPA do not. Conceptualizations of the Wernicke area that appear to conflict, therefore, can be reconciled by considering the hodologic and physiologic differences of the underlying lesions.
Keyword: Article
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340389/
http://www.ncbi.nlm.nih.gov/pubmed/30578374
https://doi.org/10.1212/WNL.0000000000006788
BASE
Hide details
8
Verb-argument integration in primary progressive aphasia: Real-time argument access and selection
In: Neuropsychologia (2019)
BASE
Show details
9
Semantic Typicality Effects in Primary Progressive Aphasia
BASE
Show details
10
Functional connectivity is reduced in early stage primary progressive aphasia when atrophy is not prominent
BASE
Show details
11
Selective verbal recognition memory impairments are associated with atrophy of the language network in non-semantic variants of primary progressive aphasia
BASE
Show details
12
Communication Bridge: A pilot feasibility study of Internet-based speech–language therapy for individuals with progressive aphasia
BASE
Show details
13
Am I looking at a cat or a dog? Gaze in the semantic variant of primary progressive aphasia is subject to excessive taxonomic capture
BASE
Show details
14
Is in vivo Amyloid Distribution Asymmetric in Primary Progressive Aphasia?
BASE
Show details
15
Asymmetric pathology in primary progressive aphasia with progranulin mutations and TDP inclusions
Kim, Garam; Ahmadian, Saman S.; Peterson, Melanie. - : Lippincott Williams & Wilkins, 2016
BASE
Show details
16
Eye Movements as Probes of Lexico-semantic Processing in a Patient with Primary Progressive Aphasia
BASE
Show details
17
Hippocampal subfield surface deformity in non-semantic primary progressive aphasia
BASE
Show details
18
The Wernicke conundrum and the anatomy of language comprehension in primary progressive aphasia
Mesulam, M.-Marsel; Thompson, Cynthia K.; Weintraub, Sandra. - : Oxford University Press, 2015
BASE
Show details
19
Asymmetry and heterogeneity of Alzheimer’s and frontotemporal pathology in primary progressive aphasia
Mesulam, M.-Marsel; Weintraub, Sandra; Rogalski, Emily J.. - : Oxford University Press, 2014
BASE
Show details
20
Primary progressive aphasia and the evolving neurology of the language network
BASE
Show details

Page: 1 2 3 4

Catalogues
0
0
6
0
0
0
0
Bibliographies
10
0
0
0
0
0
0
0
3
Linked Open Data catalogues
0
Online resources
0
0
0
0
Open access documents
55
0
0
0
0
© 2013 - 2024 Lin|gu|is|tik | Imprint | Privacy Policy | Datenschutzeinstellungen ändern