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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 4 Hits 1 – 20 of 69 1 Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathy. Korb, Manisha; Peck, Allison; Alfano, Lindsay N... In: Orphanet journal of rare diseases, vol 17, iss 1 (2022) BASE Show details 2 Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathy ... Korb, Manisha; Peck, Allison; Alfano, Lindsay N.. - : figshare, 2022 BASE Show details 3 Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathy ... Korb, Manisha; Peck, Allison; Alfano, Lindsay N.. - : figshare, 2022 BASE Show details 4 Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathy Korb, Manisha; Peck, Allison; Alfano, Lindsay N.... In: Orphanet J Rare Dis (2022) BASE Show details 5 Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification. Yang, Winson FZ; Toller, Gianina; Shdo, Suzanne. - : eScholarship, University of California, 2021 BASE Show details 6 Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification. Yang, Winson FZ; Toller, Gianina; Shdo, Suzanne. - : eScholarship, University of California, 2021 BASE Show details 7 Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification Yang, Winson F.Z.; Toller, Gianina; Shdo, Suzanne... In: Neuroimage Clin (2021) BASE Show details 8 Primary progressive aphasia and the FTD-MND spectrum disorders: clinical, pathological, and neuroimaging correlates ... Vinceti, Giulia; Olney, Nicholas; Mandelli, Maria Luisa. - : Taylor & Francis, 2020 BASE Show details 9 Primary progressive aphasia and the FTD-MND spectrum disorders: clinical, pathological, and neuroimaging correlates ... Vinceti, Giulia; Olney, Nicholas; Mandelli, Maria Luisa. - : Taylor & Francis, 2020 BASE Show details 10 Task-Free Functional Language Networks: Reproducibility and Clinical Application Battistella, Giovanni; Borghesani, Valentina; Henry, Maya; Shwe, Wendy; Lauricella, Michael; Miller, Zachary; Deleon, Jessica; Miller, Bruce L.; Dronkers, Nina; Brambati, Simona M.; Seeley, William W.; Mandelli, Maria Luisa; Gorno-Tempini, Maria Luisa In: J Neurosci (2020) Abstract: Intrinsic connectivity networks (ICNs) identified through task-free fMRI (tf-fMRI) offer the opportunity to investigate human brain circuits involved in language processes without requiring participants to perform challenging cognitive tasks. In this study, we assessed the ability of tf-fMRI to isolate reproducible networks critical for specific language functions and often damaged in primary progressive aphasia (PPA). First, we performed whole-brain seed-based correlation analyses on tf-fMRI data to identify ICNs anchored in regions known for articulatory, phonological, and semantic processes in healthy male and female controls (HCs). We then evaluated the reproducibility of these ICNs in an independent cohort of HCs, and recapitulated their functional relevance with a post hoc meta-analysis on task-based fMRI. Last, we investigated whether atrophy in these ICNs could inform the differential diagnosis of nonfluent/agrammatic, semantic, and logopenic PPA variants. The identified ICNs included a dorsal articulatory-phonological network involving inferior frontal and supramarginal regions; a ventral semantic network involving anterior middle temporal and angular gyri; a speech perception network involving superior temporal and sensorimotor regions; and a network between posterior inferior temporal and intraparietal regions likely linking visual, phonological, and attentional processes for written language. These ICNs were highly reproducible across independent groups and revealed areas consistent with those emerging from task-based meta-analysis. By comparing ICNs' spatial distribution in HCs with patients' atrophy patterns, we identified ICNs associated with each PPA variant. Our findings demonstrate the potential use of tf-fMRI to investigate the functional status of language networks in patients for whom activation studies can be methodologically challenging. SIGNIFICANCE STATEMENT We showed that a single, short, task-free fMRI acquisition is able to identify four reproducible and relatively segregated intrinsic left-dominant networks associated with articulatory, phonological, semantic, and multimodal orthography-to-phonology processes, in HCs. We also showed that these intrinsic networks relate to syndrome-specific atrophy patterns in primary progressive aphasia. Collectively, our results support the application of task-free fMRI in future research to study functionality of language circuits in patients for whom tasked-based activation studies might be methodologically challenging. Keyword: Research Articles URL: http://www.ncbi.nlm.nih.gov/pubmed/31852732 https://doi.org/10.1523/JNEUROSCI.1485-19.2019 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002153/ BASE Hide details 11 Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers. Lee, Suzee E; Sias, Ana C; Kosik, Eena L. - : eScholarship, University of California, 2019 BASE Show details 12 Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers. Lee, Suzee E; Sias, Ana C; Kosik, Eena L... In: Lee, Suzee E; Sias, Ana C; Kosik, Eena L; Flagan, Taru M; Deng, Jersey; Chu, Stephanie A; et al.(2019). Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers. NeuroImage. Clinical, 22, 101751. doi:10.1016/j.nicl.2019.101751. UCLA: Retrieved from: http://www.escholarship.org/uc/item/6vv8g8qt (2019) BASE Show details 13 Divergent patterns of loss of interpersonal warmth in frontotemporal dementia syndromes are predicted by altered intrinsic network connectivity. Toller, Gianina; Yang, Winson FZ; Brown, Jesse A... In: Toller, Gianina; Yang, Winson FZ; Brown, Jesse A; Ranasinghe, Kamalini G; Shdo, Suzanne M; Kramer, Joel H; et al.(2019). Divergent patterns of loss of interpersonal warmth in frontotemporal dementia syndromes are predicted by altered intrinsic network connectivity. NeuroImage. Clinical, 22, 101729. doi:10.1016/j.nicl.2019.101729. UCSF: Retrieved from: http://www.escholarship.org/uc/item/9qm527cr (2019) BASE Show details 14 Factors that predict diagnostic stability in neurodegenerative dementia. Perry, David C; Datta, Samir; Miller, Zachary A... In: Journal of neurology, vol 266, iss 8 (2019) BASE Show details 15 Factors that predict diagnostic stability in neurodegenerative dementia. Perry, David C; Datta, Samir; Miller, Zachary A... In: Journal of neurology, vol 266, iss 8 (2019) BASE Show details 16 Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia. Miller, Zachary A; Spina, Salvatore; Pakvasa, Mikhail... In: Brain communications, vol 1, iss 1 (2019) BASE Show details 17 Divergent patterns of loss of interpersonal warmth in frontotemporal dementia syndromes are predicted by altered intrinsic network connectivity. Toller, Gianina; Yang, Winson FZ; Brown, Jesse A. - : eScholarship, University of California, 2019 BASE Show details 18 Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers. Lee, Suzee E; Sias, Ana C; Kosik, Eena L. - : eScholarship, University of California, 2019 BASE Show details 19 Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia. Miller, Zachary A; Spina, Salvatore; Pakvasa, Mikhail... In: Brain communications, vol 1, iss 1 (2019) BASE Show details 20 Divergent patterns of loss of interpersonal warmth in frontotemporal dementia syndromes are predicted by altered intrinsic network connectivity. Toller, Gianina; Yang, Winson FZ; Brown, Jesse A. - : eScholarship, University of California, 2019 BASE Show details Page: 1 2 3 4

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