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Utilising a systematic review-based approach to create a database of individual participant data for meta- and network meta-analyses: The RELEASE database of aphasia after stroke
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In: Research outputs 2014 to 2021 (2022)
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Utilising a systematic review-based approach to create a database of individual participant data for meta- and network meta-analyses: the RELEASE database of aphasia after stroke
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In: ISSN: 0268-7038 ; EISSN: 1464-5041 ; Aphasiology ; https://hal.archives-ouvertes.fr/hal-03528818 ; Aphasiology, Taylor & Francis (Routledge), 2021, ⟨10.1080/02687038.2021.1897081⟩ (2021)
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Predictors of Poststroke Aphasia Recovery: A Systematic Review-Informed Individual Participant Data Meta-Analysis
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In: ISSN: 0039-2499 ; EISSN: 1524-4628 ; Stroke ; https://hal.archives-ouvertes.fr/hal-03277820 ; Stroke, American Heart Association, 2021, 52 (5), pp.1778-1787. ⟨10.1161/strokeaha.120.031162⟩ (2021)
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Predictors of Poststroke Aphasia Recovery A Systematic Review-Informed Individual Participant Data Meta-Analysis
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RELEASE: A protocol for a systematic review based, individual participant data, meta- and network meta-analysis, of complex speech-language therapy interventions for stroke-related aphasia
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In: Research outputs 2014 to 2021 (2020)
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RELEASE: a protocol for a systematic review based, individual participant data, meta- and network meta-analysis, of complex speech-language therapy interventions for stroke-related aphasia
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Tidier descriptions of speech and language therapy interventions for people with aphasia; consensus from the release collaboration
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In: Research outputs 2014 to 2021 (2018)
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Validation of a prediction model for long-term outcome of aphasia after stroke
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Melodic Intonation Therapy in Chronic Aphasia: Evidence from a Pilot Randomized Controlled Trial
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Abstract:
Melodic Intonation Therapy (MIT) is a language production therapy for severely non-fluent aphasic patients using melodic intoning and rhythm to restore language. Although many studies have reported its beneficial effects on language production, randomized controlled trials (RCT) examining the efficacy of MIT are rare. In an earlier publication, we presented the results of an RCT on MIT in subacute aphasia and found that MIT was effective on trained and untrained items. Further, we observed a clear trend in improved functional language use after MIT: subacute aphasic patients receiving MIT improved considerably on language tasks measuring connected speech and daily life verbal communication. Here, we present the results of a pilot RCT on MIT in chronic aphasia and compare these to the results observed in subacute aphasia. We used a multicenter waiting-list RCT design. Patients with chronic (>1 year) post-stroke aphasia were randomly allocated to the experimental group (6 weeks MIT) or to the control group (6 weeks no intervention followed by 6 weeks MIT). Assessments were done at baseline (T1), after 6 weeks (T2), and 6 weeks later (T3). Efficacy was evaluated at T2 using univariable linear regression analyses. Outcome measures were chosen to examine several levels of therapy success: improvement on trained items, generalization to untrained items, and generalization to verbal communication. Of 17 included patients, 10 were allocated to the experimental condition and 7 to the control condition. MIT significantly improved repetition of trained items (β = 13.32, p = 0.02). This effect did not remain stable at follow-up assessment. In contrast to earlier studies, we found only a limited and temporary effect of MIT, without generalization to untrained material or to functional communication. The results further suggest that the effect of MIT in chronic aphasia is more restricted than its effect in earlier stages post stroke. This is in line with studies showing larger effects of aphasia therapy in earlier compared to later stages post stroke. The study was designed as an RCT, but was underpowered. The results therefore have to be interpreted cautiously and future larger studies are needed.
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Keyword:
Neuroscience
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URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088197/
http://www.ncbi.nlm.nih.gov/pubmed/27847473
https://doi.org/10.3389/fnhum.2016.00533
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The Efficacy of Early Cognitive-Linguistic Treatment and Communicative Treatment in Aphasia after Stroke - A Randomized Controlled Trial (RATS-2)
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In: ISSN: 0022-3050 ; EISSN: 1468-330X ; Journal of Neurology, Neurosurgery and Psychiatry ; https://hal.archives-ouvertes.fr/hal-00584602 ; Journal of Neurology, Neurosurgery and Psychiatry, BMJ Publishing Group, 2010, 82 (4), pp.399. ⟨10.1136/jnnp.2010.210559⟩ (2010)
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Communication profiles in severe aphasia: the roles of supportive strategies and of the communication partner
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Recovery of linguistic deficits in stroke patients: a three-year-follow-up study
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Utilising a systematic review-based approach to create a database of individual participant data for meta- and network meta-analyses: the RELEASE database of aphasia after stroke
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