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1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans
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2
A Comparison of the ASEBA Adult Self Report (ASR) and the Brief Problem Monitor (BPM/18-59)
In: Behav Genet (2020)
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3
Novel genetic loci associated with hippocampal volume
In: ISSN: 2041-1723 ; EISSN: 2041-1723 ; Nature Communications ; https://hal.archives-ouvertes.fr/hal-01488337 ; Nature Communications, Nature Publishing Group, 2017, 8, pp.13624. ⟨10.1038/ncomms13624⟩ (2017)
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4
Novel genetic loci underlying human intracranial volume identified through genome-wide association
In: ISSN: 1097-6256 ; EISSN: 1546-1726 ; Nature Neuroscience ; https://hal.archives-ouvertes.fr/hal-01382716 ; Nature Neuroscience, Nature Publishing Group, 2016, 19 (12), pp.1569-1582. ⟨10.1038/nn.4398⟩ (2016)
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5
Common genetic variants influence human subcortical brain structures.
In: ISSN: 0028-0836 ; EISSN: 1476-4679 ; Nature ; https://hal.archives-ouvertes.fr/hal-01196805 ; Nature, Nature Publishing Group, 2015, 520 (7546), pp.224-9. ⟨10.1038/nature14101⟩ (2015)
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6
Genetic Basis of a Cognitive Complexity Metric
Hansell, Narelle K.; Halford, Graeme S.; Andrews, Glenda. - : Public Library of Science, 2015
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7
Genetic basis of a cognitive complexity metric
Hansell, Narelle K.; Halford, Graeme S.; Andrews, Glenda. - : Public Library of Science, 2015
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8
Low birth weight in MZ twins discordant for birth weight is associated with shorter telomere length and lower IQ, but not anxiety/depression in later life
Strohmaier, Jana; van Dongen, Jenny; Willemsen, Gonneke. - : Cambridge University Press, 2015
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9
Intelligence: Shared genetic basis between Mendelian disorders and a polygenic trait
Franic, Sanja; Groen-Blokhuis, Maria M.; Dolan, Conor V.. - : Nature Publishing Group, 2015
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10
Childhood intelligence is heritable, highly polygenic and associated with FNBP1L
Benyamin, B.; Pourcain, Bst; Davis, O. S.. - : Nature Publishing Group, 2014
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11
Genotype by environment interactions in cognitive ability: a survey of 14 studies from four countries covering four age groups
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12
Human brain volume : what's in the genes?
In: Handbook of behavior genetics (New York, 2009), p. 137-158
MPI für Psycholinguistik
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13
Genetics of ADHD, hyperactivity, and attention problems
In: Handbook of behavior genetics (New York, 2009), p. 361-378
MPI für Psycholinguistik
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14
Genetic contribution to variation in cognitive function: an fMRI study in twins
In: Science. - Washington, DC : AAAS, American Assoc. for the Advancement of Science 323 (2009) 5922, 1737-1740
BLLDB
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15
Genetic covariance structure of reading, intelligence and memory in children
In: Behavior genetics. - New York, NY : Springer 39 (2009) 3, 245-254
BLLDB
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16
QTL detection in multivariate data from sibling pairs
In: Statistical genetics (New York, NY, 2008), p. 239-264
MPI für Psycholinguistik
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17
The ongoing adaptive evolution of ASPM and microcephalin is not explained by increased intelligence
Abstract: Recent studies have made great strides towards identifying putative genetic events underlying the evolution of the human brain and its emergent cognitive capacities. One of the most intriguing findings is the recurrent identification of adaptive evolution in genes associated with primary microcephaly, a developmental disorder characterized by severe reduction in brain size and intelligence, reminiscent of the early hominid condition. This has led to the hypothesis that the adaptive evolution of these genes has contributed to the emergence of modern human cognition. As with other candidate loci, however, this hypothesis remains speculative due to the current lack of methodologies for characterizing the evolutionary function of these genes in humans. Two primary microcephaly genes, ASPM and Microcephalin, have been implicated not only in the adaptive evolution of the lineage leading to humans, but in ongoing selective sweeps in modern humans as well. The presence of both the putatively adaptive and neutral alleles at these loci provides a unique opportunity for using normal trait variation within humans to test the hypothesis that the recent selective sweeps are driven by an advantage in cognitive abilities. Here, we report a large-scale association study between the adaptive alleles of these genes and normal variation in several measures of IQ. Five independent samples were used, totaling 2393 subjects, including both family-based and population-based datasets. Our overall findings do not support a detectable association between the recent adaptive evolution of either ASPM or Microcephalin and changes in IQ. As we enter the post-genomic era, with the number of candidate loci underlying human evolution growing rapidly, our findings highlight the importance of direct experimental validation in elucidating their evolutionary role in shaping the human phenotype.
Keyword: 321011 Medical Genetics; 730107 Inherited diseases (incl. gene therapy); Adolescent; Adult; Alleles; C1; Child
URL: https://espace.library.uq.edu.au/view/UQ:131445
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18
Accounting for Sequential Trial Effects in the Flanker Task: Conflict Adaptation or Associative Priming?
In: Memory & cognition. - Heidelberg [u.a.] : Springer 34 (2006) 6, 1260
OLC Linguistik
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19
Accounting for sequential trial effects in the flanker task: Conflict adaptation or associative priming?
In: Memory & cognition. - Heidelberg [u.a.] : Springer 34 (2006) 6, 1260-1272
OLC Linguistik
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20
Genetic Contributions to Human Brain Morphology and Intelligence
Hulshoff Pol, Hilleke E.; Schnack, Hugo G.; Posthuma, Danielle. - : Society for Neuroscience, 2006
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