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Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool. ...
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Predicting loss of independence and mortality in frontotemporal lobar degeneration syndromes. ...
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Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool.
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Placing Matter: A Summary of a Convenient Vocabulary, for the experiencing of Metaplasticity, Spatial Assemblages and Typological Boundary Conditions
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Metabolomic changes associated with frontotemporal lobar degeneration syndromes. ...
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Redefining the multidimensional clinical phenotypes of frontotemporal lobar degeneration syndromes ...
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Predicting loss of independence and mortality in frontotemporal lobar degeneration syndromes ...
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Predicting loss of independence and mortality in frontotemporal lobar degeneration syndromes
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Metabolomic changes associated with frontotemporal lobar degeneration syndromes.
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Paracingulate Sulcus Morphology and Hallucinations in Clinical and Nonclinical Groups. ...
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Paracingulate Sulcus Morphology and Hallucinations in Clinical and Nonclinical Groups.
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Evidence for causal top-down frontal contributions to predictive processes in speech perception ...
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Cope, Thomas; Sohoglu, E; Sedley, W; Patterson, Karalyn; Jones, Simon; Wiggins, Julie; Dawson, C; Grube, M; Carlyon, Bob; Griffiths, TD; Davis, Matt; Rowe, James. - : Apollo - University of Cambridge Repository, 2017
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Abstract:
Perception relies on the integration of sensory information and prior expectations. Here we show that selective neurodegeneration of human frontal speech regions results in delayed reconciliation of predictions in temporal cortex. These temporal regions were not atrophic, displayed normal evoked magnetic and electrical power, and preserved neural sensitivity to manipulations of sensory detail. Frontal neurodegeneration does not prevent the perceptual effects of contextual information; instead, prior expectations are applied inflexibly. The precision of predictions correlates with beta power, in line with theoretical models of the neural instantiation of predictive coding. Fronto-temporal interactions are enhanced while participants reconcile prior predictions with degraded sensory signals. Excessively precise predictions can explain several challenging phenomena in frontal aphasias, including agrammatism and subjective difficulties with speech perception. This work demonstrates that higher-level frontal ... : This study was supported by the National Institute for Health Research, the Association of British Neurologists and Patrick Berthoud Charitable Trust (TEC fellowship); the Wellcome Trust (JBR Senior Fellowship, 103838); the Evelyn Trust; and the Medical Research Council Cognition and Brain Sciences unit (MC-A060-5PQ30, MC-A060-5PQ80). ...
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Keyword:
language; neurodegenerative diseases; neurophysiology
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URL: https://dx.doi.org/10.17863/cam.14401 https://www.repository.cam.ac.uk/handle/1810/268202
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Artificial grammar learning in vascular and progressive non-fluent aphasias ...
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Apathy and impulsivity in frontotemporal lobar degeneration syndromes
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Evidence for causal top-down frontal contributions to predictive processes in speech perception
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Artificial grammar learning in vascular and progressive non-fluent aphasias
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Decreased integrity of the fronto-temporal fibers of the left inferior occipito-frontal fasciculus associated with auditory verbal hallucinations in schizophrenia
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Hear today, not gone tomorrow? An exploratory longitudinal study of auditory verbal hallucinations (hearing voices)
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Finding Zelig in Text:A Measure for Normalising Linguistic Accommodation
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