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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 Hits 1 – 20 of 29 1 Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool. ... Peterson, Katie; Jones, Simon; Patel, Nikil. - : Apollo - University of Cambridge Repository, 2021 BASE Show details 2 Predicting loss of independence and mortality in frontotemporal lobar degeneration syndromes. ... Murley, Alexander; Rouse, Matthew; Coyle-Gilchrist, Ian TS. - : Apollo - University of Cambridge Repository, 2021 BASE Show details 3 Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool. Peterson, Katie; Jones, Simon; Patel, Nikil; Tsvetanov, Kamen A.; Ingram, Ruth; Cappa, Stefano F; Lambon Ralph, Matthew; Patterson, Karalyn; Garrard, Peter; Rowe, James. - : Frontiers Media SA, 2021. : Front Aging Neurosci, 2021 Abstract: Background: Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) affect speech and language as well as motor functions. Clinical and neuropathological data indicate a close relationship between these two disorders and the non-fluent variant of primary progressive aphasia (nfvPPA). We use the recently developed Mini Linguistic State Examination tool (MLSE) to study speech and language disorders in patients with PSP, CBS, and nfvPPA, in combination with structural magnetic resonance imaging (MRI). Methods: Fifty-one patients (PSP N = 13, CBS N = 19, nfvPPA N = 19) and 30 age-matched controls completed the MLSE, the short form of the Boston Diagnostic Aphasia Examination (BDAE), and the Addenbrooke's Cognitive Examination III. Thirty-eight patients and all controls underwent structural MRI at 3 Tesla, with T1 and T2-weighted images processed by surface-based and subcortical segmentation within FreeSurfer 6.0.0 to extract cortical thickness and subcortical volumes. Morphometric differences were compared between groups and correlated with the severity of speech and language impairment. Results: CBS and PSP patients showed impaired MLSE performance, compared to controls, with a similar language profile to nfvPPA, albeit less severe. All patient groups showed reduced cortical thickness in bilateral frontal regions and striatal volume. PSP and nfvPPA patients also showed reduced superior temporal cortical thickness, with additional thalamic and amygdalo-hippocampal volume reductions in nfvPPA. Multivariate analysis of brain-wide cortical thickness and subcortical volumes with MLSE domain scores revealed associations between performance on multiple speech and language domains with atrophy of left-lateralised fronto-temporal cortex, amygdala, hippocampus, putamen, and caudate. Conclusions: The effect of PSP and CBS on speech and language overlaps with nfvPPA. These three disorders cause a common anatomical pattern of atrophy in the left frontotemporal language network and striatum. The MLSE is a short clinical screening tool that can identify the language disorder of PSP and CBS, facilitating clinical management and patient access to future clinical trials. URL: https://www.repository.cam.ac.uk/handle/1810/324947 https://doi.org/10.17863/CAM.72401 BASE Hide details 4 Placing Matter: A Summary of a Convenient Vocabulary, for the experiencing of Metaplasticity, Spatial Assemblages and Typological Boundary Conditions Kay-Jones, Simon. - : Routledge, 2021 BASE Show details 5 Metabolomic changes associated with frontotemporal lobar degeneration syndromes. ... Murley, Alexander; Jones, Simon; Coyle Gilchrist, Ian. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 6 Redefining the multidimensional clinical phenotypes of frontotemporal lobar degeneration syndromes ... Murley, Alexander; Coyle-Gilchrist, Ian; Rouse, Matthew. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 7 Predicting loss of independence and mortality in frontotemporal lobar degeneration syndromes ... Murley, Alexander; Rouse, Matthew; Coyle-Gilchrist, Ian. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 8 Predicting loss of independence and mortality in frontotemporal lobar degeneration syndromes Murley, Alexander; Rouse, Matthew; Coyle-Gilchrist, Ian. - : Cold Spring Harbor Laboratory, 2020. : Journal of Neurology, Neurosurgery and Psychiatry, 2020 BASE Show details 9 Metabolomic changes associated with frontotemporal lobar degeneration syndromes. Murley, Alexander; Jones, Simon; Coyle Gilchrist, Ian. - : Springer Science and Business Media LLC, 2020. : J Neurol, 2020 BASE Show details 10 Paracingulate Sulcus Morphology and Hallucinations in Clinical and Nonclinical Groups. ... Garrison, Jane; Fernyhough, Charles; McCarthy-Jones, Simon. - : Apollo - University of Cambridge Repository, 2019 BASE Show details 11 Paracingulate Sulcus Morphology and Hallucinations in Clinical and Nonclinical Groups. Garrison, Jane; Fernyhough, Charles; McCarthy-Jones, Simon. - : Oxford University Press (OUP), 2019. : Schizophr Bull, 2019 BASE Show details 12 Evidence for causal top-down frontal contributions to predictive processes in speech perception ... Cope, Thomas; Sohoglu, E; Sedley, W. - : Apollo - University of Cambridge Repository, 2017 BASE Show details 13 Artificial grammar learning in vascular and progressive non-fluent aphasias ... Cope, Thomas; Wilson, B; Robson, H. - : Apollo - University of Cambridge Repository, 2017 BASE Show details 14 Apathy and impulsivity in frontotemporal lobar degeneration syndromes Lansdall, Claire; Coyle-Gilchrist, ITS; Jones, Simon. - : Oxford University Press, 2017. : Brain, 2017 BASE Show details 15 Evidence for causal top-down frontal contributions to predictive processes in speech perception Jones, Simon; Dawson, C; Sedley, W. - : Nature Publishing Group, 2017. : Nature Communications, 2017 BASE Show details 16 Artificial grammar learning in vascular and progressive non-fluent aphasias Cope, Thomas; Wilson, B; Robson, H. - : Elsevier, 2017. : Neuropsychologia, 2017 BASE Show details 17 Decreased integrity of the fronto-temporal fibers of the left inferior occipito-frontal fasciculus associated with auditory verbal hallucinations in schizophrenia Oestreich, Lena K. L.; McCarthy-Jones, Simon; Whitford, Thomas J.. - : Springer New York LLC, 2016 BASE Show details 18 Hear today, not gone tomorrow? An exploratory longitudinal study of auditory verbal hallucinations (hearing voices) Hartigan, Nicky; McCarthy-Jones, Simon; Hayward, Mark. - : Cambridge University Press, 2014 BASE Show details 19 Finding Zelig in Text:A Measure for Normalising Linguistic Accommodation Muir, Kate; Jones, Simon; Dewdney, Nigel. - 2014 BASE Show details 20 Content-based retrieval of human actions from realistic video databases Jones, Simon; Shao, Ling In: Information sciences. - New York, NY : Elsevier Science Inc. 236 (2013), 56-65 OLC Linguistik Show details Page: 1 2

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