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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 1 of 1 1 A JOURNAL OF NEUROLOGY OCCASIONAL PAPER ‘The quicksand of forgetfulness’: semantic dementia in One Hundred Years of Solitude Katya Rascovsky; Matthew E. Growdon; Isela R. Pardo; Scott Grossman; Bruce L. Miller In: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139943/pdf/awp100.pdf Abstract: This multidisciplinary article compares the pattern of memory loss described in Gabriel Garcı́a Márquez’s One Hundred Years of Solitude to that exhibited by patients with semantic dementia (SD). In his renowned novel, Garcı́a Márquez depicts the plight of Macondo, a town struck by the dreaded insomnia plague. The most devastating symptom of the plague is not the impossibility of sleep, but rather the loss of ‘the name and notion of things’. In an effort to combat this insidious loss of knowledge, the protagonist, Jose ́ Arcadio Buendı́a, ‘marked everything with its name: table, chair, clock, door, wall, bed, pan’. ‘Studying the infinite possibilities of a loss of memory, he realized that the day might come when things would be recognized by their inscriptions but that no one would remember their use’. The cognitive impairments experienced by Macondo’s inhabitants are remarkably similar to those observed in SD, a clinical syndrome characterized by a progressive breakdown of conceptual knowledge (semantic memory) in the context of relatively preserved day-to-day (episodic) memory. First recognized in 1975, it is now considered one of the main variants of frontotemporal lobar degeneration. Writing within the realm of magical realism and investigating the power of language as a form of communication, Garcı́a Márquez provides beautiful descriptions of the loss of ‘the name and notion of things ’ typical of the syndrome. He further speculates on ways to cope with this dissolution of meaning, ranging from ‘the spell of an imaginary reality ’ to Jose ́ Arcadio’s ‘memory machine’, strategies that resonate with attempts by semantic dementia patients to cope with their disease. Remarkably, Garcı́a Márquez created a striking literary depiction of collective semantic dementia before the syndrome was recognized in neurology. The novel also provides an Keyword: Gabriel Garcı́a Márquez; One Hundred Years of S; semantic dementia URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139943/pdf/awp100.pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.689.5396 BASE Hide details

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