1 |
Investigating the effect of changing parameters when building prediction models in post-stroke aphasia
|
|
|
|
In: Nat Hum Behav (2020)
|
|
Abstract:
Neuroimaging has radically improved our understanding of how speech and language abilities map to the brain in normal and impaired participants, including the diverse, graded variations observed in post-stroke aphasia. A handful of studies have begun to explore the reverse inference: creating brain-to-behaviour prediction models. In this study, we explored the effect of three critical parameters on model performance: (1) brain partitions as predictive features; (2) combination of multimodal neuroimaging; and (3) type of machine learning algorithms. We explored the influence of these factors while predicting four principal dimensions of language and cognition variation in post-stroke aphasia. Across all four behavioural dimensions, we consistently found that prediction models derived from diffusion weighted data did not improve performance over and above models using structural measures extracted from T1 scans. Our results provide a set of principles to guide future work aiming to predict outcomes in neurological patients from brain imaging data.
|
|
Keyword:
Article
|
|
URL: https://doi.org/10.1038/s41562-020-0854-5 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116235/ http://www.ncbi.nlm.nih.gov/pubmed/32313234
|
|
BASE
|
|
Hide details
|
|
2 |
Auditory, Phonological, and Semantic Factors in the Recovery From Wernicke’s Aphasia Poststroke: Predictive Value and Implications for Rehabilitation ...
|
|
|
|
BASE
|
|
Show details
|
|
3 |
Auditory, Phonological, and Semantic Factors in the Recovery From Wernicke’s Aphasia Poststroke: Predictive Value and Implications for Rehabilitation ...
|
|
|
|
BASE
|
|
Show details
|
|
4 |
SD-squared revisited: reply to Coltheart, Tree, and Saunders (2010). ...
|
|
|
|
BASE
|
|
Show details
|
|
5 |
Predicting the pattern and severity of chronic post-stroke language deficits from functionally-partitioned structural lesions
|
|
|
|
BASE
|
|
Show details
|
|
6 |
Triangulation of language-cognitive impairments, naming errors and their neural bases post-stroke
|
|
|
|
BASE
|
|
Show details
|
|
7 |
Seeing the Meaning: Top–Down Effects on Letter Identification
|
|
|
|
BASE
|
|
Show details
|
|
8 |
Laterality of anterior temporal lobe repetitive transcranial magnetic stimulation determines the degree of disruption in picture naming
|
|
|
|
BASE
|
|
Show details
|
|
10 |
Do You Read How I Read? Systematic Individual Differences in Semantic Reliance amongst Normal Readers
|
|
|
|
BASE
|
|
Show details
|
|
11 |
Taking Sides: An Integrative Review of the Impact of Laterality and Polarity on Efficacy of Therapeutic Transcranial Direct Current Stimulation for Anomia in Chronic Poststroke Aphasia
|
|
|
|
BASE
|
|
Show details
|
|
12 |
Lexical is as lexical does: computational approaches to lexical representation
|
|
|
|
BASE
|
|
Show details
|
|
13 |
Opposing Effects of Semantic Diversity in Lexical and Semantic Relatedness Decisions
|
|
|
|
BASE
|
|
Show details
|
|
14 |
Processing deficits for familiar and novel faces in patients with left posterior fusiform lesions
|
|
|
|
BASE
|
|
Show details
|
|
15 |
Triangulation of the neurocomputational architecture underpinning reading aloud
|
|
|
|
BASE
|
|
Show details
|
|
18 |
Capturing multidimensionality in stroke aphasia: mapping principal behavioural components to neural structures
|
|
|
|
BASE
|
|
Show details
|
|
19 |
Capturing multidimensionality in stroke aphasia: mapping principal behavioural components to neural structures
|
|
|
|
BASE
|
|
Show details
|
|
20 |
Connectionist neuropsychology: uncovering ultimate causes of acquired dyslexia
|
|
|
|
BASE
|
|
Show details
|
|
|
|