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Cortical microstructure in primary progressive aphasia: a multicenter study.
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In: Alzheimer's research & therapy, vol 14, iss 1 (2022)
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Survival in Korean Patients with Frontotemporal Dementia Syndrome: Association with Behavioral Features and Parkinsonism
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In: Journal of Clinical Medicine; Volume 11; Issue 8; Pages: 2260 (2022)
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Pilotstudie zur parodontalen Gesundheit bei Patienten mit frontotemporaler Demenz ...
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A 'Mini Linguistic State Examination' to classify primary progressive aphasia. ...
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A 'Mini Linguistic State Examination' to classify primary progressive aphasia. ...
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Temporal cognition: subjective time and its connection with memory in frontotemporal dementia
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Liu, Lulu. - : The University of Sydney, 2022. : Faculty of Science, School of Psychology, 2022
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Improving the diagnostic accuracy of primary progressive aphasia using cognitive tests
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Foxe, David Gordon. - : The University of Sydney, 2022. : Faculty of Science, School of Psychology, 2022
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Primary Progressive Aphasia Associated With GRN Mutations: New Insights Into the Non-amyloid Logopenic Variant
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In: ISSN: 0028-3878 ; EISSN: 1526-632X ; Neurology ; https://hal.archives-ouvertes.fr/hal-03281660 ; Neurology, American Academy of Neurology, 2021, ⟨10.1212/wnl.0000000000012174⟩ (2021)
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Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification.
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Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.
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In: Alzheimer's & dementia (Amsterdam, Netherlands), vol 13, iss 1 (2021)
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Social Behavior Observer Checklist: Patterns of Spontaneous Behaviors Differentiate Patients With Neurodegenerative Disease From Healthy Older Adults.
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Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification.
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What Do We Mean by Behavioral Disinhibition in Frontotemporal Dementia?
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Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.
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Staffaroni, Adam M; Weintraub, Sandra; Rascovsky, Katya; Rankin, Katherine P; Taylor, Jack; Fields, Julie A; Casaletto, Kaitlin B; Hillis, Argye E; Lukic, Sladjana; Gorno-Tempini, Maria Luisa; Heuer, Hilary; Teylan, Merilee A; Kukull, Walter A; Miller, Bruce L; Boeve, Bradley F; Rosen, Howard J; Boxer, Adam L; Kramer, Joel H
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In: Alzheimer's & dementia (Amsterdam, Netherlands), vol 13, iss 1 (2021)
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Abstract:
IntroductionThe Frontotemporal Lobar Degeneration Module (FTLD-MOD) includes a neuropsychological battery designed to assess the clinical features of FTLD, although much is unknown about its utility. We investigated FTLD-MOD and Uniform Data Set 3.0 (UDS) language tests for differential diagnosis and disease monitoring.MethodsLinear regressions compared baseline performances in 1655 National Alzheimer's Coordinating Center participants (behavioral variant frontotemporal dementia (bvFTD, n=612), semantic variant primary progressive aphasia (svPPA, n=168), non-fluent/agrammatic variant PPA (nfvPPA, n=168), logopenic variant PPA (lvPPA, n=109), and controls (n=581)). Sample sizes to detect treatment effects were estimated using longitudinal data.ResultsAmong PPAs, the FTLD-MOD language tasks and UDS Multilingual Naming Test accurately discriminated svPPA. Number Span Forward best discriminated lvPPA; Phonemic:Semantic Fluency ratio was excellent for nfvPPA classification. UDS fluency and naming measures required the smallest sample size to detect meaningful change.DiscussionThe FTLD-MOD and UDS differentiated among PPA subtypes. UDS 3.0 measures performed best for longitudinal monitoring.
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Keyword:
Acquired Cognitive Impairment; Aging; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Alzheimer's Disease Related Dementias (ADRD); Aphasia; Brain Disorders; Clinical Research; clinical trials; Clinical Trials and Supportive Activities; cognition; Dementia; differential diagnosis; endpoints; frontotemporal dementia; Frontotemporal Dementia (FTD); FTLD module; Genetics; longitudinal; Neurodegenerative; neuropsychology; Neurosciences; primary progressive aphasia; Rare Diseases; speech
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URL: https://escholarship.org/uc/item/31v6d3qh
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What Do We Mean by Behavioral Disinhibition in Frontotemporal Dementia?
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Conceptual framework for the definition of preclinical and prodromal frontotemporal dementia. ...
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Application of Machine Learning to Electroencephalography for the Diagnosis of Primary Progressive Aphasia: A Pilot Study
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In: Brain Sciences ; Volume 11 ; Issue 10 (2021)
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Verbal Short-Term Memory Disturbance in the Primary Progressive Aphasias: Challenges and Distinctions in a Clinical Setting
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In: Brain Sciences ; Volume 11 ; Issue 8 (2021)
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Cognitive and Neural Mechanisms of Social Communication Dysfunction in Primary Progressive Aphasia
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In: Brain Sciences; Volume 11; Issue 12; Pages: 1600 (2021)
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Semantic Variant Primary Progressive Aphasia: Practical Recommendations for Treatment from 20 Years of Behavioural Research
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In: Brain Sciences ; Volume 11 ; Issue 12 (2021)
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