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Proton magnetic resonance spectroscopy in frontotemporal lobar degeneration-related syndromes
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In: Neurobiol Aging (2022)
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Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool. ...
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Peterson, Katie A; Jones, P Simon; Patel, Nikil; Tsvetanov, Kamen A; Ingram, Ruth; Cappa, Stefano F; Lambon Ralph, Matthew A; Patterson, Karalyn; Garrard, Peter; Rowe, James B. - : Apollo - University of Cambridge Repository, 2021
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Abstract:
Background : Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) affect speech and language as well as motor functions. Clinical and neuropathological data indicate a close relationship between these two disorders and the non-fluent variant of primary progressive aphasia (nfvPPA). We use the recently developed Mini Linguistic State Examination tool (MLSE) to study speech and language disorders in patients with PSP, CBS, and nfvPPA, in combination with structural magnetic resonance imaging (MRI). Methods : Fifty-one patients (PSP N = 13, CBS N = 19, nfvPPA N = 19) and 30 age-matched controls completed the MLSE, the short form of the Boston Diagnostic Aphasia Examination (BDAE), and the Addenbrooke's Cognitive Examination III. Thirty-eight patients and all controls underwent structural MRI at 3 Tesla, with T1 and T2-weighted images processed by surface-based and subcortical segmentation within FreeSurfer 6.0.0 to extract cortical thickness and subcortical volumes. Morphometric differences were ...
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Keyword:
Aphasia; Corticobasal Syndrome; Language; Progressive Supranuclear Palsy; Speech
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URL: https://dx.doi.org/10.17863/cam.75354 https://www.repository.cam.ac.uk/handle/1810/327900
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Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool ...
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Proton magnetic resonance spectroscopy in frontotemporal lobar degeneration-related syndromes ...
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Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool
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In: Front Aging Neurosci (2021)
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Metabolomic changes associated with frontotemporal lobar degeneration syndromes
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Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool
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Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool.
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In: essn: 1663-4365 ; nlmid: 101525824 (2021)
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Metabolomic changes associated with frontotemporal lobar degeneration syndromes ...
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Metabolomic changes associated with frontotemporal lobar degeneration syndromes ...
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Metabolomic changes associated with frontotemporal lobar degeneration syndromes
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Redefining the multidimensional clinical phenotypes of frontotemporal lobar degeneration syndromes
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In: Brain (2020)
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Metabolomic changes associated with frontotemporal lobar degeneration syndromes
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In: J Neurol (2020)
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[18F]AV-1451 binding in vivo mirrors the expected distribution of TDP-43 pathology in the semantic variant of primary progressive aphasia
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Artificial grammar learning in vascular and progressive non-fluent aphasias
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The Effect of Aging on the Neural Correlates of Phonological Word Retrieval
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A comparison of VLSM and VBM in a cohort of patients with post-stroke aphasia☆
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The neural correlates of inner speech defined by voxel-based lesion-symptom mapping
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The neural correlates of inner speech defined by voxel-based lesion–symptom mapping
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