1 |
Family history of FXTAS is associated with age-related cognitive-linguistic decline among mothers with the FMR1 premutation.
|
|
|
|
In: Journal of neurodevelopmental disorders, vol 14, iss 1 (2022)
|
|
BASE
|
|
Show details
|
|
2 |
Family history of FXTAS is associated with age-related cognitive-linguistic decline among mothers with the FMR1 premutation
|
|
|
|
In: J Neurodev Disord (2022)
|
|
BASE
|
|
Show details
|
|
3 |
Concurrent Associations between Expressive Language Ability and Independence in Adolescents and Adults with Fragile X Syndrome.
|
|
|
|
In: Brain sciences, vol 11, iss 9 (2021)
|
|
BASE
|
|
Show details
|
|
4 |
Concurrent Associations between Expressive Language Ability and Independence in Adolescents and Adults with Fragile X Syndrome.
|
|
|
|
In: Brain sciences, vol 11, iss 9 (2021)
|
|
Abstract:
BackgroundFew individuals with fragile X syndrome (FXS) successfully meet adult normative expectations in education, employment, peer relations, and habitation, although there is within-syndrome variability in this regard. The primary goal of this study was to determine whether expressive language skills contribute to the capacity for independent functioning in adulthood even after controlling for nonverbal cognitive ability.MethodsParticipants were 18- to 23-year-olds with FXS. Expressive language was assessed using the psychometrically validated Expressive Language Sampling (ELS) conversation and narration procedures. The language produced was transcribed and analyzed to yield measures of expressive vocabulary, syntax, and intelligibility. Parents concurrently completed questionnaires on the independent functioning of the participants with FXS.ResultsAll three ELS measures were significantly corelated with multiple measures of independence. The magnitudes of the correlations were reduced when nonverbal IQ was controlled through partial correlation. Nonetheless, many of the partial correlations were medium to large and several were statistically significant.ConclusionsExpressive language skills appear to contribute uniquely to the capacity for independence, although longitudinal data are needed to evaluate the possibility of a bidirectional relationship between these domains. Thus, language intervention may be a prerequisite for preparing youth with FXS for an independent adult life.
|
|
Keyword:
Behavioral and Social Science; Brain Disorders; Clinical Research; Cognitive Sciences; daily living skills; expressive language; fragile X syndrome; independent functioning; Intellectual and Developmental Disabilities (IDD); Mental Health; Neurosciences; Pediatric; Psychology; Rare Diseases
|
|
URL: https://escholarship.org/uc/item/4g58z81c
|
|
BASE
|
|
Hide details
|
|
5 |
Concurrent Associations between Expressive Language Ability and Independence in Adolescents and Adults with Fragile X Syndrome
|
|
|
|
In: Brain Sci (2021)
|
|
BASE
|
|
Show details
|
|
6 |
Reading in Children With Fragile X Syndrome: Phonological Awareness and Feasibility of Intervention.
|
|
|
|
In: American journal on intellectual and developmental disabilities, vol 123, iss 3 (2018)
|
|
BASE
|
|
Show details
|
|
7 |
Curvilinear Association Between Language Disfluency and FMR1 CGG Repeat Size Across the Normal, Intermediate, and Premutation Range.
|
|
|
|
In: Frontiers in genetics, vol 9, iss AUG (2018)
|
|
BASE
|
|
Show details
|
|
8 |
Curvilinear Association Between Language Disfluency and FMR1 CGG Repeat Size Across the Normal, Intermediate, and Premutation Range.
|
|
|
|
In: Klusek, Jessica; Porter, Anna; Abbeduto, Leonard; Adayev, Tatyana; Tassone, Flora; Mailick, Marsha R; et al.(2018). Curvilinear Association Between Language Disfluency and FMR1 CGG Repeat Size Across the Normal, Intermediate, and Premutation Range. Frontiers in genetics, 9(AUG), 344. doi:10.3389/fgene.2018.00344. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/0dn6p4z8 (2018)
|
|
BASE
|
|
Show details
|
|
9 |
Reading in Children with Fragile X Syndrome: Phonological Awareness and Feasibility of Intervention
|
|
|
|
BASE
|
|
Show details
|
|
10 |
Pragmatic Language Features of Mothers with the FMR1 Premutation are Associated with the Language Outcomes of Adolescents and Young Adults with Fragile X Syndrome
|
|
|
|
In: Faculty Publications (2016)
|
|
BASE
|
|
Show details
|
|
11 |
Reading and Phonological Skills in Boys with Fragile X Syndrome ...
|
|
|
|
BASE
|
|
Show details
|
|
12 |
Reading and Phonological Skills in Boys with Fragile X Syndrome
|
|
|
|
BASE
|
|
Show details
|
|
13 |
Reading and Phonological Skills in Boys with Fragile X Syndrome
|
|
|
|
In: Faculty Publications (2015)
|
|
BASE
|
|
Show details
|
|
14 |
Cardiac Autonomic Regulation in Autism and Fragile X Syndrome: A Review
|
|
|
|
BASE
|
|
Show details
|
|
15 |
Phonological Awareness and Reading in Boys with Fragile X Syndrome
|
|
|
|
BASE
|
|
Show details
|
|
16 |
Social Communication and Theory of Mind in Boys with Autism and Fragile X Syndrome
|
|
|
|
BASE
|
|
Show details
|
|
|
|