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1
Lesions that do or do not impair digit span: a study of 816 stroke survivors
In: Brain Commun (2021)
Abstract: Prior studies have reported inconsistency in the lesion sites associated with verbal short-term memory impairments. Here we asked: How many different lesion sites can account for selective impairments in verbal short-term memory that persist over time, and how consistently do these lesion sites impair verbal short-term memory? We assessed verbal short-term memory impairments using a forward digit span task from the Comprehensive Aphasia Test. First, we identified the incidence of digit span impairments in a sample of 816 stroke survivors (541 males/275 females; age at stroke onset 56 ± 13 years; time post-stroke 4.4 ± 5.2 years). Second, we studied the lesion sites in a subgroup of these patients (n = 39) with left hemisphere damage and selective digit span impairment—defined as impaired digit span with unimpaired spoken picture naming and spoken word comprehension (tests of speech production and speech perception, respectively). Third, we examined how often these lesion sites were observed in patients who either had no digit span impairments or digit span impairments that co-occurred with difficulties in speech perception and/or production tasks. Digit span impairments were observed in 222/816 patients. Almost all (199/222 = 90%) had left hemisphere damage to five small regions in basal ganglia and/or temporo-parietal areas. Even complete damage to one or more of these five regions was not consistently associated with persistent digit span impairment. However, when the same regions were spared, only 5% (23/455) presented with digit span impairments. These data suggest that verbal short-term memory impairments are most consistently associated with damage to left temporo-parietal and basal ganglia structures. Sparing of these regions very rarely results in persistently poor verbal short-term memory. These findings have clinical implications for predicting recovery of verbal short-term memory after stroke.
Keyword: Original Article
URL: https://doi.org/10.1093/braincomms/fcab031
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066865/
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2
Damage to Broca’s area does not contribute to long-term speech production outcome after stroke
In: Brain (2021)
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3
A Data-Based Approach for Selecting Pre- and Intra-Operative Language Mapping Tasks
In: Front Neurosci (2021)
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4
Right hemisphere structural adaptation and changing language skills years after left hemisphere stroke
Hope, Thomas M. H.; Leff, Alex P.; Prejawa, Susan. - : Oxford University Press, 2017
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5
Language Control and Lexical Competition in Bilinguals: An Event-Related fMRI Study
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6
Dissociating the semantic function of two neighbouring subregions in the left lateral anterior temporal lobe
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7
A Trade-Off between Somatosensory and Auditory Related Brain Activity during Object Naming But Not Reading
Seghier, Mohamed L.; Hope, Thomas M.H.; Prejawa, Susan. - : Society for Neuroscience, 2015
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8
Comparing language outcomes in monolingual and bilingual stroke patients
Hope, Thomas M. H.; Parker Jones, ‘Ōiwi; Grogan, Alice. - : Oxford University Press, 2015
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9
Inter- and Intrahemispheric Connectivity Differences When Reading Japanese Kanji and Hiragana
Kawabata Duncan, Keith J.; Twomey, Tae; Parker Jones, ‘Ōiwi. - : Oxford University Press, 2014
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10
Dissecting the functional anatomy of auditory word repetition
Hope, Thomas M. H.; Prejawa, Susan; Parker Jones, ‘Ōiwi. - : Frontiers Media S.A., 2014
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11
The Importance of Premotor Cortex for Supporting Speech Production after Left Capsular-Putaminal Damage
Seghier, Mohamed L.; Bagdasaryan, Juliana; Jung, Dorit E.. - : Society for Neuroscience, 2014
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12
Sensory-to-motor integration during auditory repetition: a combined fMRI and lesion study
Parker Jones, ‘Ōiwi; Prejawa, Susan; Hope, Thomas M. H.. - : Frontiers Media S.A., 2014
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13
Dissociating frontal regions that co-lateralize with different ventral occipitotemporal regions during word processing
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 126 (2013) 2, 133-140
OLC Linguistik
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14
The Angular Gyrus: Multiple Functions and Multiple Subdivisions
Seghier, Mohamed L.. - : SAGE Publications, 2013
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15
Inter- and Intrahemispheric Connectivity Differences When Reading Japanese Kanji and Hiragana
Kawabata Duncan, Keith J.; Twomey, Tae; Parker Jones, Oiwi. - : Oxford University Press, 2013
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16
Inter- and Intrahemispheric Connectivity Differences When Reading Japanese Kanji and Hiragana
Kawabata Duncan, Keith J.; Twomey, Tae; Parker Jones, Oiwi. - : Oxford University Press, 2013
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17
Auditory–motor interactions for the production of native and non-native speech
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18
Reading without the left ventral occipito-temporal cortex
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19
Where, When and Why Brain Activation Differs for Bilinguals and Monolinguals during Picture Naming and Reading Aloud
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20
Where, When and Why Brain Activation Differs for Bilinguals and Monolinguals during Picture Naming and Reading Aloud
Parker Jones, ‘Oiwi; Green, David W.; Grogan, Alice. - : Oxford University Press, 2012
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