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Genetic admixture of Chinese Tajik people inferred from genome-wide array genotyping and mitochondrial genome sequencing ...
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Genetic admixture of Chinese Tajik people inferred from genome-wide array genotyping and mitochondrial genome sequencing ...
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Intensive phototherapy vs. exchange transfusion for the treatment of neonatal hyperbilirubinemia: a multicenter retrospective cohort study
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In: Chin Med J (Engl) (2022)
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Fine-Scale Population Admixture Landscape of Tai–Kadai-Speaking Maonan in Southwest China Inferred From Genome-Wide SNP Data
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In: Front Genet (2022)
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Level of Orthographic Knowledge Helps to Reveal Automatic Predictions in Visual Word Processing
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In: Front Neurosci (2022)
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Ectatosticta pingwuensis Wang & Zhao & Irfan & Zhang 2021, sp. nov. ...
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Ectatosticta pingwuensis Wang & Zhao & Irfan & Zhang 2021, sp. nov. ...
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Ectatosticta shennongjiaensis Wang & Zhao & Irfan & Zhang 2021, sp. nov. ...
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Ectatosticta shennongjiaensis Wang & Zhao & Irfan & Zhang 2021, sp. nov. ...
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The Graded Priming Effect of Semantic Radical on Chinese Character Recognition
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In: Front Psychol (2021)
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The Trans-Ancestral Genomic Architecture of Glycemic Traits
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In: Nat Genet (2021)
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Use of Adaptive Feedback in an App for English Language Spontaneous Speech
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In: Artificial Intelligence in Education (2020)
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All data for [Development of neural specialization for print: Evidence for predictive coding in visual word recognition](Zhao Jing 2019) ...
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All data for [Development of neural specialization for print: Evidence for predictive coding in visual word recognition](Zhao Jing 2019) ...
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Improving sentence reading performance in Chinese children with developmental dyslexia by training based on visual attention span
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Translatomics: The Global View of Translation
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Abstract:
In all kingdoms of life, proteins are synthesized by ribosomes in a process referred to as translation. The amplitude of translational regulation exceeds the sum of transcription, mRNA degradation and protein degradation. Therefore, it is essential to investigate translation in a global scale. Like the other “omics”-methods, translatomics investigates the totality of the components in the translation process, including but not limited to translating mRNAs, ribosomes, tRNAs, regulatory RNAs and nascent polypeptide chains. Technical advances in recent years have brought breakthroughs in the investigation of these components at global scale, both for their composition and dynamics. These methods have been applied in a rapidly increasing number of studies to reveal multifaceted aspects of translation control. The process of translation is not restricted to the conversion of mRNA coding sequences into polypeptide chains, it also controls the composition of the proteome in a delicate and responsive way. Therefore, translatomics has extended its unique and innovative power to many fields including proteomics, cancer research, bacterial stress response, biological rhythmicity and plant biology. Rational design in translation can enhance recombinant protein production for thousands of times. This brief review summarizes the main state-of-the-art methods of translatomics, highlights recent discoveries made in this field and introduces applications of translatomics on basic biological and biomedical research.
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Keyword:
Review
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URL: https://doi.org/10.3390/ijms20010212 http://www.ncbi.nlm.nih.gov/pubmed/30626072 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337585/
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Using Gestures and Body Movements for Thinking and Learning
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Increased deficit of visual attention span with development in Chinese children with developmental dyslexia
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