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ЛИНГВИСТИЧЕСКИЕ И ЭКСТРАЛИНГВИСТИЧЕСКИЕ СВОЙСТВА ВИРУСНОЙ РЕКЛАМЫ ... : LINGUISTIC AND EXTRALINGUISTIC PROPERTIES OF VIRAL ADVERTISING ...
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И.А. Юрина. - : Мир науки, культуры, образования, 2021
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ТАНЕЦ TIKTOK КАК ФЕНОМЕН СОВРЕМЕННОЙ ТАНЦЕВАЛЬНОЙ КУЛЬТУРЫ ... : TIKTOK DANCE AS A PHENOMENON OF MODERN DANCE CULTURE ...
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Discursive resonances built upon the English textbook in Pará state in times of crisis ; Ressonâncias discursivas construídas sobre o uso do LD de inglês no Pará em tempos de crise
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In: Revista Horizontes de Linguistica Aplicada; Vol. 20 No. 1 (2021): Dossiê "Ensino de línguas em tempos de crise" e Fluxo contínuo; DT4 ; Revista Horizontes de Linguistica Aplicada; v. 20 n. 1 (2021): Dossiê "Ensino de línguas em tempos de crise" e Fluxo contínuo; DT4 ; 2237-0951 ; 1677-9770 ; 10.26512/rhla.v20i1 (2021)
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Investigating the Concept and Origin of Viruses
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In: ISSN: 0966-842X ; Trends in Microbiology ; https://hal-amu.archives-ouvertes.fr/hal-03141377 ; Trends in Microbiology, Elsevier, 2020, 28 (12), pp.959-967. ⟨10.1016/j.tim.2020.08.003⟩ (2020)
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More Than Smell-COVID-19 Is Associated With Severe Impairment of Smell, Taste, and Chemesthesis.
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In: Chemical senses, vol 45, iss 7 (2020)
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Inter Organizational Practice Committee Recommendations/Guidance for Teleneuropsychology in Response to the COVID-19 Pandemic†.
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In: Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, vol 35, iss 6 (2020)
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Test to Protect Family and Self—A Hepatitis B Screening and Care-Linkage Initiative In the Coastal Mississippi Vietnamese Community
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In: Faculty Publications (2020)
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THE EVOLUTION OF THE HEADLINE – FROM PRINT TO PATTERNS AND VIRALITY (AN OVERVIEW OF RESEARCH IN ENGLISH AND BULGARIAN)
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In: Studies in Linguistics, Culture, and FLT, Vol 4, Pp 55-69 (2018) (2018)
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West Nile Virus and Pattern Recognition Receptors
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In: Journal of Health Disparities Research and Practice (2016)
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Potential Cost Savings of Not Doing CD4 Counts in HIV Positive People In Rhode Island With An Undetectable Viral Load
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In: Journal of Health Disparities Research and Practice (2016)
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A Unique 5′ Translation Element Discovered in Triticum Mosaic Virus
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Abstract:
Several plant viruses encode elements at the 5′ end of their RNAs, which, unlike most cellular mRNAs, can initiate translation in the absence of a 5′ m7GpppG cap. Here, we describe an exceptionally long (739-nucleotide [nt]) leader sequence in triticum mosaic virus (TriMV), a recently emerged wheat pathogen that belongs to the Potyviridae family of positive-strand RNA viruses. We demonstrate that the TriMV 5′ leader drives strong cap-independent translation in both wheat germ extract and oat protoplasts through a novel, noncanonical translation mechanism. Translation preferentially initiates at the 13th start codon within the leader sequence independently of eIF4E but involves eIF4G. We truncated the 5′ leader to a 300-nucleotide sequence that drives cap-independent translation from the 5′ end. We show that within this sequence, translation activity relies on a stem-loop structure identified at nucleotide positions 469 to 490. The disruption of the stem significantly impairs the function of the 5′ untranslated region (UTR) in driving translation and competing against a capped RNA. Additionally, the TriMV 5′ UTR can direct translation from an internal position of a bicistronic mRNA, and unlike cap-driven translation, it is unimpaired when the 5′ end is blocked by a strong hairpin in a monocistronic reporter. However, the disruption of the identified stem structure eliminates such a translational advantage. Our results reveal a potent and uniquely controlled translation enhancer that may provide new insights into mechanisms of plant virus translational regulation.
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Keyword:
Genome Replication and Regulation of Viral Gene Expression
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URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665250/
https://doi.org/10.1128/JVI.02099-15
http://www.ncbi.nlm.nih.gov/pubmed/26423954
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Dendritic cell-based therapeutic vaccine elicits polyfunctional HIV-specific T-cell immunity associated with control of viral load.
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In: ISSN: 0014-2980 ; EISSN: 1521-4141 ; European Journal of Immunology ; https://hal.inria.fr/hal-01108024 ; European Journal of Immunology, Wiley-VCH Verlag, 2014, 44 (9), pp.2802-10 (2014)
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The 3′ Untranslated Region of Pea Enation Mosaic Virus Contains Two T-Shaped, Ribosome-Binding, Cap-Independent Translation Enhancers
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