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Researching oral production skills of young learners ; Raziskovanje spretnosti govornega izrazanja mlajsih ucencev
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In: CEPS Journal 2 (2012) 3, S. 141-166 (2012)
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Current policy issues in early foreign language learning ... : Aktualne dileme politik na podrocju zgodnjega ucenja tujih jezikov ...
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"Ihr müsst (...) sprachlich homogene Gruppen bilden" – eine Fallstudie zur interkulturellen Bildungspraxis ...
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Expertise "Erfolgreiche Sprachförderung unter Berücksichtigung der besonderen Situation Berlins" ...
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Ergebnisse einer Elternbefragung in Kindergärten mit deutscher Unterrichtssprache aus Rumänien
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In: Neue Didaktik (2012) 1, S. 106-124 (2012)
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Examine the Impact of Training Duration on Retention
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In: DTIC (2012)
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An Aetiological Foxp2 Mutation Causes Aberrant Striatal Activity and Alters Plasticity during Skill Learning
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: Nature Publishing Group, 2012
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Abstract:
Abstract Mutations in the human FOXP2 gene cause impaired speech development and linguistic deficits, which have been best characterized in a large pedigree called the KE family. The encoded protein is highly conserved in many vertebrates and is expressed in homologous brain regions required for sensorimotor integration and motor-skill learning, in particular cortico-striatal circuits. Independent studies in multiple species suggest that the striatum is a key site of FOXP2 action. Here we used in vivo recordings in awake behaving mice to investigate the effects of the KE-family mutation on the function of striatal circuits during motor-skill learning. We uncovered abnormally high ongoing striatal activity in mice carrying an identical mutation to that of the KE-family. Furthermore, there were dramatic alterations in striatal plasticity during the acquisition of a motor-skill, with most neurons in mutants showing negative modulation of firing rate, starkly contrasting with the predominantly positive modulation seen in control animals. We also observed striking changes in the temporal coordination of striatal firing during motor-skill learning in mutants. Our results indicate that FOXP2 is critical for the function of striatal circuits in vivo, which are important not only for speech but also for other striatal-dependent skills. ; ruicosta@fchampalimaud.org (Costa, Rui M) ; Champalimaud Neuroscience Programme - Rua da Quinta Grande 6, Oeiras, Portugal 2780-901--> - PORTUGAL (Costa, Rui M) ; Champalimaud Neuroscience Programme - Rua da Quinta Grande 6, Oeiras, Portugal 2780-901--> - PORTUGAL (French, Catherine Ann) ; Champalimaud Neuroscience Programme - Rua da Quinta Grande 6, Oeiras, Portugal 2780-901--> - PORTUGAL (Jin, Xin) ; Champalimaud Neuroscience Programme - Rua da Quinta Grande 6, Oeiras, Portugal 2780-901--> - PORTUGAL (Campbell, Thomas G) ; Champalimaud Neuroscience Programme - Rua da Quinta Grande 6, Oeiras, Portugal 2780-901--> - PORTUGAL (Gerfen, Elissa) ; Champalimaud Neuroscience Programme - Rua da Quinta Grande 6, Oeiras, Portugal 2780-901--> - PORTUGAL (Groszer, Matthias) ; Champalimaud Neuroscience Programme - Rua da Quinta Grande 6, Oeiras, Portugal 2780-901--> - PORTUGAL (Fisher, Simon) ; PORTUGAL ; Accepted: 2011-06-03 ; Received: 2011-01-20 ; Revised: 2011-05-24
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Keyword:
Foxp2; in vivo recording; KE family; motor-skill learning; speech and language; striatum
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URL: http://hdl.handle.net/2262/62440 https://doi.org/10.1038/mp.2011.105
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Dysphagia training for speech-language pathologists: implications for clinical practice
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DEVELOPING INSTRUCTIONAL MATERIALS ON ENGLISH ORAL COMMUNICATION FOR NURSING SCHOOLS
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In: TEFLIN Journal, Vol 23, Iss 1, Pp 44-59 (2012) (2012)
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DEVELOPING INSTRUCTIONAL MATERIALS ON ENGLISH ORAL COMMUNICATION FOR NURSING SCHOOLS
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In: TEFLIN Journal, Vol 23, Iss 1, Pp 44-59 (2012) (2012)
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A Pedagogic Approach to FASP : Erin Brockovich and Class Action in the USA ; Approche pédagogique de la FASP : Erin Brockovich et la « class action » aux États-Unis
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In: ISSN: 2257-5405 ; EISSN: 2119-5242 ; Recherche et Pratiques Pédagogiques en Langues de Spécialité : Cahiers de l'APLIUT ; https://hal.archives-ouvertes.fr/hal-01325535 ; Recherche et Pratiques Pédagogiques en Langues de Spécialité : Cahiers de l'APLIUT, Association des Professeurs de Langues des IUT (APLIUT), 2011 ; https://apliut.revues.org/779 (2011)
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An Aetiological Mutation Causes Aberrant Striatal Activity and Alters Plasticity during Skill Learning
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In: ISSN: 1359-4184 ; EISSN: 1476-5578 ; Molecular Psychiatry ; https://hal.archives-ouvertes.fr/hal-00675395 ; Molecular Psychiatry, Nature Publishing Group, 2011, ⟨10.1038/mp.2011.105⟩ (2011)
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"Begegnung findet eigentlich nicht statt." Probleme von Begegnungsschulen im postkolonialen Kontext ...
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L'improvisation théâtrale au service de l'expression orale et écrite et de son enseignement ... : Theaterimprovisation im Dienst des mündlichen und schriftlichen Ausdrucks in der Schule ...
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L'improvisation théâtrale au service de l'expression orale et écrite et de son enseignement ; Theaterimprovisation im Dienst des mündlichen und schriftlichen Ausdrucks in der Schule
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In: Schweizerische Zeitschrift für Bildungswissenschaften 33 (2011) 2, S. 251-265 (2011)
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Potential and limitations of peace education in Israel. A case study on parents’ perspectives on the Hand in Hand school in Jerusalem
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Cölsch, Nele. - : Centaurus-Verl., 2011. : Freiburg, Br., 2011. : pedocs-Dokumentenserver/DIPF, 2011
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In: Freiburg, Br. : Centaurus-Verl. 2011, 119 S. - (Gender and Diversity; 3) (2011)
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"Begegnung findet eigentlich nicht statt." Probleme von Begegnungsschulen im postkolonialen Kontext
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In: ZEP : Zeitschrift für internationale Bildungsforschung und Entwicklungspädagogik 34 (2011) 2, S. 24-29 (2011)
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Potential and limitations of peace education in Israel. A case study on parents’ perspectives on the Hand in Hand school in Jerusalem ...
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Language and Culture Training: Opportunities Exist to Improve Visibility and Sustainment of Knowledge and Skills in Army and Marine Corps General Purpose Forces
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In: DTIC (2011)
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