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1
Four functionally distinct regions in the left supramarginal gyrus support word processing
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2
Code-switching and language control
In: BILINGUALISM-LANGUAGE AND COGNITION , 19 (5) pp. 883-884. (2016) (2016)
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3
Neuroimaging of language control in bilinguals: Neural adaptation and reserve
In: Bilingualism , 19 (4) pp. 689-698. (2016) (In press). (2016)
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4
Four Functionally Distinct Regions in the Left Supramarginal Gyrus Support Word Processing
In: CEREBRAL CORTEX , 26 (11) pp. 4212-4226. (2016) (2016)
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5
Comparing language outcomes in monolingual and bilingual stroke patients.
In: Brain , 138 (Pt 4) 1070 - 1083. (2015) (2015)
Abstract: Post-stroke prognoses are usually inductive, generalizing trends learned from one group of patients, whose outcomes are known, to make predictions for new patients. Research into the recovery of language function is almost exclusively focused on monolingual stroke patients, but bilingualism is the norm in many parts of the world. If bilingual language recruits qualitatively different networks in the brain, prognostic models developed for monolinguals might not generalize well to bilingual stroke patients. Here, we sought to establish how applicable post-stroke prognostic models, trained with monolingual patient data, are to bilingual stroke patients who had been ordinarily resident in the UK for many years. We used an algorithm to extract binary lesion images for each stroke patient, and assessed their language with a standard tool. We used feature selection and cross-validation to find 'good' prognostic models for each of 22 different language skills, using monolingual data only (174 patients; 112 males and 62 females; age at stroke: mean = 53.0 years, standard deviation = 12.2 years, range = 17.2-80.1 years; time post-stroke: mean = 55.6 months, standard deviation = 62.6 months, range = 3.1-431.9 months), then made predictions for both monolinguals and bilinguals (33 patients; 18 males and 15 females; age at stroke: mean = 49.0 years, standard deviation = 13.2 years, range = 23.1-77.0 years; time post-stroke: mean = 49.2 months, standard deviation = 55.8 months, range = 3.9-219.9 months) separately, after training with monolingual data only. We measured group differences by comparing prediction error distributions, and used a Bayesian test to search for group differences in terms of lesion-deficit associations in the brain. Our models distinguish better outcomes from worse outcomes equally well within each group, but tended to be over-optimistic when predicting bilingual language outcomes: our bilingual patients tended to have poorer language skills than expected, based on trends learned from monolingual data alone, and this was significant (P < 0.05, corrected for multiple comparisons) in 13/22 language tasks. Both patient groups appeared to be sensitive to damage in the same sets of regions, though the bilinguals were more sensitive than the monolinguals. media-1vid1 10.1093/brain/awv020_video_abstract awv020_video_abstract.
Keyword: aphasia; bilingualism; language; prognosis; stroke
URL: http://discovery.ucl.ac.uk/1462690/
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6
The neuroprotective effects of bilingualism upon the inferior parietal lobule: A Structural Neuroimaging Study in Aging Chinese Bilinguals
In: Journal of Neurolinguistics , 33 3 - 13. (2015) (2015)
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7
Bilingualism protects anterior temporal lobe integrity in aging
In: Neurobiology of Aging , 35 (9) 2126 - 2133. (2014) (2014)
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8
Sensory-to-motor integration during auditory repetition: a combined fMRI and lesion study.
In: Front Hum Neurosci , 8 , Article 24 . (2014) (2014)
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9
Bilingualism protects anterior temporal lobe integrity in aging
In: Neurobiology of Aging (2014) (2014)
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10
Individual variability and neuroplastic changes
In: Applied Psycholinguistics , 35 (5) 910 - 912. (2014) (2014)
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11
A control process model of code-switching
In: LANGUAGE COGNITION AND NEUROSCIENCE , 29 (4) 499 - 511. (2014) (2014)
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12
Dissecting the functional anatomy of auditory word repetition.
In: Front Hum Neurosci , 8 , Article 246 . (2014) (2014)
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13
Functionally distinct contributions of the anterior and posterior putamen during sublexical and lexical reading.
In: Front Hum Neurosci , 7 , Article 787 . (2013) (2013)
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14
Convergence, Degeneracy, and Control
In: In: (2013) (2013)
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15
Language proficiency modulates the engagement of cognitive control areas in multilinguals
In: Cortex , 49 (3) 905 - 911. (2013) (2013)
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16
Language control in bilinguals: The adaptive control hypothesis
In: Journal of Cognitive Psychology , 25 (5) 515 - 530. (2013) (2013)
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17
Auditory-motor interactions for the production of speech in native and non-native speech
In: The Journal of Neuroscience , 33 (6) pp. 2376-2387. (2013) (2013)
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18
Language control in bilinguals: The adaptive control hypothesis
In: Journal of Cognitive Psychology (2013) (2013)
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19
Cognitive control for language switching in bilinguals: A quantitative meta-analysis of functional neuroimaging studies
In: Language and Cognitive Processes , 27 (10) 1479 - 1488. (2012) (2012)
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20
Where, when and why brain activation differs for bilinguals and monolinguals during picture naming and reading aloud.
In: Cereb Cortex , 22 (4) 892 - 902. (2012) (2012)
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