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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 9 of 9 1 Evidence for a neurophysiologic auditory deficit in children with benign epilepsy with centro-temporal spikes. Liasis, A; Bamiou, DE; Boyd, S; Towell, A In: J Neural Transm (Vienna) , 113 (7) pp. 939-949. (2006) (2006) Abstract: Benign focal epilepsy in childhood with centro-temporal spikes (BECTS) is one of the most common forms of epilepsy. Recent studies have questioned the benign nature of BECTS, as they have revealed neuropsychological deficits in many domains including language. The aim of this study was to investigate whether the epileptic discharges during the night have long-term effects on auditory processing, as reflected on electrophysiological measures, during the day, which could underline the language deficits. In order to address these questions we recorded base line electroencephalograms (EEG), sleep EEG and auditory event related potentials in 12 children with BECTS and in age- and gender-matched controls. In the children with BECTS, 5 had unilateral and 3 had bilateral spikes. In the 5 patients with unilateral spikes present during sleep, an asymmetry of the auditory event related component (P85-120) was observed contralateral to the side of epileptiform activity compared to the normal symmetrical vertex distribution that was noted in all controls and in 3 the children with bilateral spikes. In all patients the peak to peak amplitude of this event related potential component was statistically greater compared to the controls. Analysis of subtraction waveforms (deviant - standard) revealed no evidence of a mismatch negativity component in any of the children with BECTS. We propose that the abnormality of P85-120 and the absence of mismatch negativity during wake recordings in this group may arise in response to the long-term effects of spikes occurring during sleep, resulting in disruption of the evolution and maintenance of echoic memory traces. These results may indicate that patients with BECTS have abnormal processing of auditory information at a sensory level ipsilateral to the hemisphere evoking spikes during sleep. Keyword: Acoustic Stimulation; Action Potentials; Auditory; Auditory Diseases; Auditory Pathways; Brain; Brain Mapping; Central; Child; Electroencephalography; Epilepsy; Evoked Potentials; Female; Functional Laterality; Humans; Language Development Disorders; Male; Neural Conduction; Predictive Value of Tests; Reaction Time; Rolandic; Time URL: http://discovery.ucl.ac.uk/74274/ BASE Hide details 2 Speech and non-speech processing in hemispherectomised children: an event-related potential study. Liasis, A; Boyd, S; Rivera-Gaxiola, M... In: Brain Res Cogn Brain Res , 17 (3) pp. 665-673. (2003) (2003) BASE Show details 3 Speech and non-speech processing in hemispherectomised children: an event-related potential study Liasis, A.; Boyd, S.; Rivera-Gaxiola, M.. - 2003 BASE Show details 4 Intracranial identification of an electric frontal-cortex response to auditory stimulus change: a case study. Liasis, A; Towell, A; Alho, K... In: Brain Res Cogn Brain Res , 11 (2) 227 - 233. (2001) (2001) BASE Show details 5 Intracranial identification of an electric frontal-cortex response to auditory stimulus change: a case study Boyd, S.; Alho, K.; Liasis, A.. - 2001 BASE Show details 6 Neurophysiological markers of central auditory processing deficits in normal hearing and language developed children. Towell, A; Liasis, A; Campbell, P... In: EUROPEAN JOURNAL OF NEUROSCIENCE , 12 169 - 169. (2000) (2000) BASE Show details 7 Intracranial auditory detection and discrimination potentials as substrates of echoic memory in children. Liasis, A; Towell, A; Boyd, S In: Brain Res Cogn Brain Res , 7 (4) 503 - 506. (1999) (1999) BASE Show details 8 Selective epileptic gait disorder. Neville, B G; Boyd, S G. - : BMJ Publishing Group Ltd, 1995 BASE Show details 9 Selective epileptic gait disorder. Neville, B G; Boyd, S G. - 1995 BASE Show details

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