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1
Longitudinal changes in brains of patients with fluent primary progressive aphasia
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 131 (2014), 11-19
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2
The direction of word stress processing in German: evidence from a working memory paradigm
Domahs, Frank; Grande, Marion; Huber, Walter. - : Frontiers Media S.A., 2014
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3
The neural correlates of agrammatism: Evidence from aphasic and healthy speakers performing an overt picture description task
Abstract: Functional brain imaging studies have improved our knowledge of the neural localization of language functions and the functional reorganization after a lesion. However, the neural correlates of agrammatic symptoms in aphasia remain largely unknown. The present fMRI study examined the neural correlates of morpho-syntactic encoding and agrammatic errors in continuous language production by combining three approaches. First, the neural mechanisms underlying natural morpho-syntactic processing in a picture description task were analyzed in 15 healthy speakers. Second, agrammatic-like speech behavior was induced in the same group of healthy speakers to study the underlying functional processes by limiting the utterance length. In a third approach, five agrammatic participants performed the picture description task to gain insights in the neural correlates of agrammatism and the functional reorganization of language processing after stroke. In all approaches, utterances were analyzed for syntactic completeness, complexity, and morphology. Event-related data analysis was conducted by defining every clause-like unit (CLU) as an event with its onset-time and duration. Agrammatic and correct CLUs were contrasted. Due to the small sample size as well as heterogeneous lesion sizes and sites with lesion foci in the insula lobe, inferior frontal, superior temporal and inferior parietal areas the activation patterns in the agrammatic speakers were analyzed on a single subject level. In the group of healthy speakers, posterior temporal and inferior parietal areas were associated with greater morpho-syntactic demands in complete and complex CLUs. The intentional manipulation of morpho-syntactic structures and the omission of function words were associated with additional inferior frontal activation. Overall, the results revealed that the investigation of the neural correlates of agrammatic language production can be reasonably conducted with an overt language production paradigm.
Keyword: Psychology
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968764
http://www.ncbi.nlm.nih.gov/pubmed/24711802
https://doi.org/10.3389/fpsyg.2014.00246
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4
Effects of lexicality and word frequency on brain activation in dyslexic readers
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 125 (2013) 2, 194-202
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5
Computer-assisted analysis of spontaneous speech: quantification of basic parameters in aphasic and unimpaired language
In: Clinical linguistics & phonetics. - London : Informa Healthcare 26 (2012) 8, 661-680
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6
The Role of Human Parietal Area 7A as a Link between Sequencing in Hand Actions and in Overt Speech Production ...
Heim, Stefan; Amunts, Katrin; Hensel, Tanja. - : RWTH Aachen University, 2012
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7
The Role of Human Parietal Area 7A as a Link between Sequencing in Hand Actions and in Overt Speech Production
Heim, Stefan; Amunts, Katrin; Hensel, Tanja. - : Frontiers Media S.A., 2012
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8
Taboo: a novel paradigm to elicit aphasia-like trouble-indicating behaviour in normally speaking individuals
In: Journal of psycholinguistic research. - New York, NY ; London [u.a.] : Springer 40 (2011) 5-6, 307-326
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9
Interaction of phonological awareness and 'magnocellular' processing during normal and dyslexic reading: behavioural and fMRI investigations
In: Dyslexia. - Bracknell : British Dyslexia Association 16 (2010) 3, 258-282
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10
Basic parameters of spontaneous speech as a sensitive method for measuring change during the course of aphasia
In: International journal of language & communication disorders. - Oxford : Wiley-Blackwell 43 (2008) 4, 408-426
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11
Measuring change in spontaneous speech production during the course of aphasia: Computer-assisted analysis of basic parameters
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12
Using a connectionist model in aphasia therapy for naming disorders
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 95 (2005) 1, 102-104
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13
An fMRI study on conceptual, grammatical, and morpho-phonological processing
In: Brain and cognition. - San Diego, Calif. [u.a.] : Elsevier Science 57 (2005) 2, 131-134
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14
Different levels of lexical processing : evidence from an fMRI study with normal subjects and aphasic patients
In: Stem-, Spraak- en Taalpathologie. - Nijmegen : Univ. Press 13 (2005) 1, 49-55
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15
Computergestützte Spontansprachanalyse zur Unterscheidung von Restaphasikern und Sprachgesunden
In: Neurolinguistik. - Aachen : Hochsch.-Verl. Verl.-Gruppe Mainz 13 (1999) 2, 71-86
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