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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 4 Hits 1 – 20 of 61 1 Digital Speech Analysis in Progressive Supranuclear Palsy and Corticobasal Syndromes Parjane, Natalia; Cho, Sunghye; Ash, Sharon... In: J Alzheimers Dis (2021) BASE Show details 2 Automated analysis of lexical features in Frontotemporal Degeneration Cho, Sunghye; Nevler, Naomi; Ash, Sharon... In: Cortex (2021) BASE Show details 3 Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium Miyagawa, Toji; Brushaber, Danielle; Syrjanen, Jeremy... In: Alzheimers Dement (2020) BASE Show details 4 C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts Costa, Beatrice; Manzoni, Claudia; Bernal-Quiros, Manuel... In: Neurology (2020) BASE Show details 5 Automated analysis of natural speech in amyotrophic lateral sclerosis spectrum disorders Nevler, Naomi; Ash, Sharon; McMillan, Corey; Elman, Lauren; McCluskey, Leo; Irwin, David J.; Cho, Sunghye; Liberman, Mark; Grossman, Murray In: Neurology (2020) Abstract: OBJECTIVE: We implemented automated methods to analyze speech and evaluate the hypothesis that cognitive and motor factors impair prosody in partially distinct ways in patients with amyotrophic lateral sclerosis (ALS). METHODS: We recruited 213 participants, including 67 with ALS (44 with motor ALS, 23 with ALS and frontotemporal degeneration [FTD]), 33 healthy controls, and neurodegenerative reference groups with behavioral variant FTD (n = 90) and nonfluent/agrammatic primary progressive aphasia (n = 23). Digitized, semistructured speech samples obtained from picture descriptions were automatically segmented with a Speech Activity Detector; continuous speech segments were pitch-tracked; and duration measures for speech and silent pause segments were extracted. Acoustic measures were calculated, including fundamental frequency (f0) range, mean speech and pause segment durations, total speech duration, and pause rate (pause count per minute of speech). Group comparisons related performance on acoustic measures to clinical scales of cognitive and motor impairments and explored MRI cortical thinning in ALS and ALS-FTD. RESULTS: The f0 range was significantly impaired in ALS spectrum disorders and was related to bulbar motor disease, and regression analyses related this to cortical thickness in primary motor cortex and perisylvian regions. Impaired speech and pause duration measures were related to the degree of cognitive impairment in ALS spectrum disorders, and regressions related duration measures to bilateral frontal opercula and left anterior insula. CONCLUSION: Automated analyses of acoustic speech properties dissociate motor and cognitive components of speech deficits in ALS spectrum disorders. Keyword: Article URL: http://www.ncbi.nlm.nih.gov/pubmed/32675077 https://doi.org/10.1212/WNL.0000000000010366 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713725/ BASE Hide details 6 Automated analysis of lexical features in Frontotemporal Degeneration Cho, Sunghye; Nevler, Naomi; Ash, Sharon... In: medRxiv (2020) BASE Show details 7 A Longitudinal Study of Speech Production in Primary Progressive Aphasia and Behavioral Variant Frontotemporal Dementia Ash, Sharon; Nevler, Naomi; Phillips, Jeffrey... In: Brain Lang (2019) BASE Show details 8 PRIMARY PROGRESSIVE APHASIA AND STROKE APHASIA Grossman, Murray; Irwin, David J. In: Continuum (Minneap Minn) (2018) BASE Show details 9 Prevalence of Amyloid-β Pathology in Distinct Variants of Primary Progressive Aphasia Bergeron, David; Gorno-Tempini, Maria L.; Rabinovici, Gil D.. - 2018 BASE Show details 10 Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia Giannini, Lucia A.A.; Irwin, David J.; McMillan, Corey T.. - : Lippincott Williams & Wilkins, 2017 BASE Show details 11 Linguistic Aspects of Primary Progressive Aphasia Grossman, Murray. - 2017 BASE Show details 12 Tau PET Imaging Predicts Cognition in Atypical Variants of Alzheimer’s Disease Phillips, Jeffrey S.; Das, Sandhitsu R.; McMillan, Corey T.. - 2017 BASE Show details 13 Neocortical Origin and Progression of Grey Matter Atrophy In Non-Amnestic Alzheimer’s Disease Phillips, Jeffrey S.; Re, Fulvio Da; Dratch, Laynie. - 2017 BASE Show details 14 Longitudinal decline in speech production in Parkinson's disease spectrum disorders Ash, Sharon; Jester, Charles; York, Collin. - 2017 BASE Show details 15 Transcranial direct current stimulation for the treatment of primary progressive aphasia: An open-label pilot study Gervits, Felix; Ash, Sharon; Coslett, H. Branch. - 2016 BASE Show details 16 Dissociation of Quantifiers and Object Nouns in Speech in Focal Neurodegenerative Disease Ash, Sharon; Ternes, Kylie; Bisbing, Teagan. - 2016 BASE Show details 17 ARTERIAL SPIN LABELING PERFUSION PREDICTS LONGITUDINAL DECLINE IN SEMANTIC VARIANT PRIMARY PROGRESSIVE APHASIA Olm, Christopher A.; Kandel, Benjamin M.; Avants, Brain B.. - 2016 BASE Show details 18 Dissociable substrates underlie the production of abstract and concrete nouns Cousins, Katheryn AQ; Ash, Sharon; Irwin, David J. - 2016 BASE Show details 19 How the brain learns how few are “many”: An fMRI study of the flexibility of quantifier semantics Heim, Stefan; McMillan, Corey T.; Clark, Robin. - 2015 BASE Show details 20 Acoustic richness modulates the neural networks supporting intelligible speech processing Lee, Yune-Sang; Min, Nam Eun; Wingfield, Arthur. - 2015 BASE Show details Page: 1 2 3 4

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