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1
Parkinson’s Disease Cognitive Phenotypes Show Unique Clock Drawing Features When Measured with Digital Technology
In: J Parkinsons Dis (2021)
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2
Phenotyping Cognitive Impairment using Graphomotor and Latency Features in Digital Clock Drawing Test
In: Annu Int Conf IEEE Eng Med Biol Soc (2020)
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3
Visuospatial Performance in Patients with Statistically-Defined Mild Cognitive Impairment
In: J Clin Exp Neuropsychol (2020)
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4
Visuoconstructional Impairment in Subtypes of Mild Cognitive Impairment
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5
Comparative semantic profiles in semantic dementia and Alzheimer's disease
Abstract: Patients with the semantic variant of primary progressive aphasia, also known as semantic dementia, and Alzheimer’s disease have deficits in semantic memory. However, few comparative studies have been performed to determine whether these patient groups have distinct semantic memory impairments. We asked 15 patients with semantic variant primary progressive aphasia and 57 patients with Alzheimer’s disease to judge semantic category membership of coloured photos and printed words that are members of familiar natural and manufactured categories, and we related performance to grey matter atrophy. We found that both semantic variant primary progressive aphasia and Alzheimer’s disease are significantly impaired on this task. Moreover, patients with semantic variant primary progressive aphasia had a significantly more prominent deficit for natural objects than their own deficit judging manufactured objects. Both semantic variant primary progressive aphasia and Alzheimer’s disease had atrophy that included portions of the left temporal lobe. Regression analyses related performance in semantic variant primary progressive aphasia to ventral and medial portions of the left temporal lobe, while regression analyses in Alzheimer’s disease related performance to these ventral and medial temporal areas as well as lateral temporal-parietal regions in the left hemisphere. We conclude that both semantic variant primary progressive aphasia and Alzheimer’s disease are significantly impaired in a simple category membership judgement task and the selective impairment for natural kinds in semantic variant primary progressive aphasia is related in part to disease in visual association cortex in ventral–medial portions of the left temporal lobe. We discuss factors that may contribute to the semantic memory deficit in semantic variant primary progressive aphasia.
Keyword: Original Articles
URL: https://doi.org/10.1093/brain/awt165
http://brain.oxfordjournals.org/cgi/content/short/136/8/2497
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6
Sparse canonical correlation analysis relates network-level atrophy to multivariate cognitive measures in a neurodegenerative population
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7
Comparative semantic profiles in semantic dementia and Alzheimer’s disease
Libon, David J.; Rascovsky, Katya; Powers, John. - : Oxford University Press, 2013
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8
Sentence processing in Lewy body spectrum disorder: the role of working memory
In: Brain and cognition. - San Diego, Calif. [u.a.] : Elsevier Science 78 (2012) 2, 85-93
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9
Yes/No Versus Forced-Choice Recognition Memory in Mild Cognitive Impairment and Alzheimer’s Disease: Patterns of Impairment and Associations with Dementia Severity
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10
SENTENCE PROCESSING IN LEWY BODY SPECTRUM DISORDER: THE ROLE OF WORKING MEMORY
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11
The Philadelphia Brief Assessment of Cognition (PBAC): A Validated Screening Measure for Dementia
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12
The importance of multiple assessments of object knowledge in semantic dementia: The case of the familiar objects task
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13
Neuropsychological Decline in Frontotemporal Lobar Degeneration: A Longitudinal Analysis
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14
Longitudinal Patterns of Semantic and Episodic Memory in Frontotemporal Lobar Degeneration and Alzheimer’s Disease
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15
Neuropsychological patterns in magnetic resonance imaging-defined subgroups of patients with degenerative dementia
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