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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 4 5...47 Hits 1 – 20 of 936 1 Effectively teaching cultural competence in healthcare education Ferebee, Shelby. - 2022 BASE Show details 2 Cortical microstructure in primary progressive aphasia: a multicenter study. Illán-Gala, Ignacio; Montal, Victor; Borrego-Écija, Sergi; Mandelli, Maria Luisa; Falgàs, Neus; Welch, Ariane E; Pegueroles, Jordi; Santos-Santos, Miguel; Bejanin, Alexandre; Alcolea, Daniel; Dols-Icardo, Oriol; Belbin, Olivia; Sánchez-Saudinós, Mª Belén; Bargalló, Nuria; González-Ortiz, Sofía; Lladó, Albert; Blesa, Rafael; Dickerson, Bradford C; Rosen, Howard J; Miller, Bruce L; Lleó, Alberto; Gorno-Tempini, Maria Luisa; Sánchez-Valle, Raquel; Fortea, Juan In: Alzheimer's research & therapy, vol 14, iss 1 (2022) Abstract: BackgroundCortical mean diffusivity is a novel imaging metric sensitive to early changes in neurodegenerative syndromes. Higher cortical mean diffusivity values reflect microstructural disorganization and have been proposed as a sensitive biomarker that might antedate macroscopic cortical changes. We aimed to test the hypothesis that cortical mean diffusivity is more sensitive than cortical thickness to detect cortical changes in primary progressive aphasia (PPA).MethodsIn this multicenter, case-control study, we recruited 120 patients with PPA (52 non-fluent, 31 semantic, and 32 logopenic variants; and 5 GRN-related PPA) as well as 89 controls from three centers. The 3-Tesla MRI protocol included structural and diffusion-weighted sequences. Disease severity was assessed with the Clinical Dementia Rating scale. Cortical thickness and cortical mean diffusivity were computed using a surface-based approach.ResultsThe comparison between each PPA variant and controls revealed cortical mean diffusivity increases and cortical thinning in overlapping regions, reflecting the canonical loci of neurodegeneration of each variant. Importantly, cortical mean diffusivity increases also expanded to other PPA-related areas and correlated with disease severity in all PPA groups. Cortical mean diffusivity was also increased in patients with very mild PPA when only minimal cortical thinning was observed and showed a good correlation with measures of disease severity.ConclusionsCortical mean diffusivity shows promise as a sensitive biomarker for the study of the neurodegeneration-related microstructural changes in PPA. Keyword: 2.1 Biological and endogenous factors; Acquired Cognitive Impairment; Aging; Alzheimer's disease; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Alzheimer’s disease; Aphasia; Biomedical Imaging; Brain Disorders; Case-Control Studies; Clinical Research; Dementia; Diffusion; Diffusion Magnetic Resonance Imaging; Frontotemporal Dementia (FTD); Frontotemporal lobar degeneration; Humans; Magnetic resonance; Magnetic Resonance Imaging; Medical and Health Sciences; Neurodegenerative; Neurological; Neurosciences; Primary Progressive; Primary progressive aphasia; Rare Diseases URL: https://escholarship.org/uc/item/4td346vg BASE Hide details 3 INGLIZ TILI FANINI BILINGUAL O‘QITISH VA FAKULTATIV DARSLAR UCHUN CASE STUDY METODIDAN FOYDALANISH ... Bog‘Dagul Faxriddinovna Qarshiyeva. - : Academic research in educational sciences, 2022 BASE Show details 4 An Empirical Study of Factors Affecting Language-Independent Models Liu, Xiaotong; Xu, Anbang; Akkiraju, Rama. - 2022 BASE Show details 5 Effect Sizes of Deletions and Duplications on Autism Risk Across the Genome Douard, Elise; Zeribi, Abderrahim; Schramm, Catherine... In: ISSN: 0002-953X ; EISSN: 1535-7228 ; American Journal of Psychiatry ; https://hal-pasteur.archives-ouvertes.fr/pasteur-03325371 ; American Journal of Psychiatry, American Psychiatric Publishing, 2021, 178 (1), pp.87-98. ⟨10.1176/appi.ajp.2020.19080834⟩ (2021) BASE Show details 6 High-Stakes Education: Dual Language Immersion in Portland, Oregon MacLean, Andrew In: University Honors Theses (2021) BASE Show details 7 Sources of Individual Differences in Adults’ ICT Skills: A Large-Scale Empirical Test of a New Guiding Framework Wicht, Alexandra; Reder, Stephen; Lechner, Clemens M. In: Applied Linguistics Faculty Publications and Presentations (2021) BASE Show details 8 Einzelfallorientierung in der Evidenzbasierung der Sprachtherapie* / Case orientation in evidence-based practice of speech language therapy ... Kohler, Jürgen; Starke, Anja; Kohmäscher, Anke. - : Zenodo, 2021 BASE Show details 9 Einzelfallorientierung in der Evidenzbasierung der Sprachtherapie* / Case orientation in evidence-based practice of speech language therapy ... Kohler, Jürgen; Starke, Anja; Kohmäscher, Anke. - : Zenodo, 2021 BASE Show details 10 Tim Low’s open textbook journey Masuku, Bianca; Willmers, Michelle; Trotter, Henry. - 2021 BASE Show details 11 Jonathan Shock’s open textbook journey Masuku, Bianca; Willmers, Michelle; Trotter, Henry. - 2021 BASE Show details 12 "We, As Parents, Do Have a Voice": Learning From Community-Based Programs Effectively Engaging Parents in Urban Communities Johnson, Ashley; Gil, Elizabeth In: GSE Faculty Publications (2021) BASE Show details 13 From policy framework to practice real work : exploring knowledge mobilisation within a complex adaptive system Craig, Anne-Marie. - : University of St Andrews, 2021. : The University of St Andrews, 2021 BASE Show details 14 Self-Translation of Mathematical Texts in Seventeenth-Century France: The Cases of Pascal, Mersenne and Hérigone Morris, S. - : University of Exeter, 2021. : Modern Languages, 2021 BASE Show details 15 A short-term training clinic model for dialectical behavior therapy (DBT) in treating borderline personality disorder (BPD): the case of "Jane" Marks, Michael Warren (author); Fishman, Daniel (chair); Rizvi, Shireen (member). - 2021 BASE Show details 16 The infinite and contradiction: A history of mathematical physics by dialectical approach Ueki, Ichiro. - 2021 BASE Show details 17 What’s in a thought experiment: the role of gender in Alan Turing’s progressive imitation game Gonçalves, Bernardo. - 2021 BASE Show details 18 Secondary school science teachers’ Pedagogical Content Knowledge (PCK) in their classroom practice Tufail, Imran. - : The University of Waikato, 2021 BASE Show details 19 A study on the impact of interpreter intervention in the Maltese Criminal Courts Torpiano, Gabrielle; Salaets, Heidi; Flynn, Peter. - : EUT Edizioni Università di Trieste, 2021 BASE Show details 20 BORN OR MADE: PROBLEMS OF PROSE STYLE & STYLISTIC IMPROVABILITY AT THE SENTENCE LEVEL, AN INTERDISCIPLINARY APPROACH McCarthy, Hope Petrash. - 2021 BASE Show details Page: 1 2 3 4 5...47

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