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1
The Trans-Ancestral Genomic Architecture of Glycemic Traits
In: Nat Genet (2021)
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2
Measurement of single-diffractive dijet production in proton-proton collisions at $\sqrt{s} =$ 8 TeV with the CMS and TOTEM experiments
In: Eur.Phys.J.C ; https://hal.archives-ouvertes.fr/hal-02507664 ; Eur.Phys.J.C, 2020, 80 (12), pp.1164. ⟨10.1140/epjc/s10052-020-08562-y⟩ (2020)
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3
Measurement of the top quark mass with lepton+jets final states using $\mathrm {p}$ $\mathrm {p}$ collisions at $\sqrt{s}=13\,\text {TeV} $
In: http://infoscience.epfl.ch/record/275278 (2020)
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4
Measurement of prompt and nonprompt charmonium suppression in $\text {PbPb}$ collisions at 5.02 $\,\text {Te}\text {V}$
In: Eur.Phys.J.C ; https://hal.archives-ouvertes.fr/hal-01833739 ; Eur.Phys.J.C, 2018, 78 (6), pp.509. ⟨10.1140/epjc/s10052-018-5950-6⟩ (2018)
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5
Measurement of prompt and nonprompt charmonium suppression in $\text {PbPb}$ collisions at 5.02 $\,\text {Te}\text {V}$
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6
Necessity Research on Reflecting “Student Oriented” Education From Ecoaesthetics
In: Cross-Cultural Communication; Vol 11, No 12 (2015): Cross-Cultural Communication; 113-117 ; 1923-6700 ; 1712-8358 (2015)
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7
Analysis and Prediction of Translation Rate Based on Sequence and Functional Features of the mRNA
Abstract: Protein concentrations depend not only on the mRNA level, but also on the translation rate and the degradation rate. Prediction of mRNA's translation rate would provide valuable information for in-depth understanding of the translation mechanism and dynamic proteome. In this study, we developed a new computational model to predict the translation rate, featured by (1) integrating various sequence-derived and functional features, (2) applying the maximum relevance & minimum redundancy method and incremental feature selection to select features to optimize the prediction model, and (3) being able to predict the translation rate of RNA into high or low translation rate category. The prediction accuracies under rich and starvation condition were 68.8% and 70.0%, respectively, evaluated by jackknife cross-validation. It was found that the following features were correlated with translation rate: codon usage frequency, some gene ontology enrichment scores, number of RNA binding proteins known to bind its mRNA product, coding sequence length, protein abundance and 5′UTR free energy. These findings might provide useful information for understanding the mechanisms of translation and dynamic proteome. Our translation rate prediction model might become a high throughput tool for annotating the translation rate of mRNAs in large-scale.
Keyword: Research Article
URL: http://www.ncbi.nlm.nih.gov/pubmed/21253596
https://doi.org/10.1371/journal.pone.0016036
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017080
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