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1
Fine-Scale Human Population Structure in Southern Africa Reflects Ecogeographic Boundaries.
In: Genetics, vol 204, iss 1 (2016)
Abstract: Recent genetic studies have established that the KhoeSan populations of southern Africa are distinct from all other African populations and have remained largely isolated during human prehistory until ∼2000 years ago. Dozens of different KhoeSan groups exist, belonging to three different language families, but very little is known about their population history. We examine new genome-wide polymorphism data and whole mitochondrial genomes for >100 South Africans from the ≠Khomani San and Nama populations of the Northern Cape, analyzed in conjunction with 19 additional southern African populations. Our analyses reveal fine-scale population structure in and around the Kalahari Desert. Surprisingly, this structure does not always correspond to linguistic or subsistence categories as previously suggested, but rather reflects the role of geographic barriers and the ecology of the greater Kalahari Basin. Regardless of subsistence strategy, the indigenous Khoe-speaking Nama pastoralists and the N|u-speaking ≠Khomani (formerly hunter-gatherers) share ancestry with other Khoe-speaking forager populations that form a rim around the Kalahari Desert. We reconstruct earlier migration patterns and estimate that the southern Kalahari populations were among the last to experience gene flow from Bantu speakers, ∼14 generations ago. We conclude that local adoption of pastoralism, at least by the Nama, appears to have been primarily a cultural process with limited genetic impact from eastern Africa.
Keyword: Africa; African Continental Ancestry Group; ancestry; Developmental Biology; DNA; Ethnic Groups; Gene Flow; Genetics; Genotype; Haplotypes; Humans; KhoeSan; Mitochondrial; pastoralism; Phylogeny; Phylogeography; Polymorphism; Population; population structure; Single Nucleotide; Southern
URL: https://escholarship.org/uc/item/70x1z7zj
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2
A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome ...
Torgerson, Dara G.; Levin, Albert M.; Wilson, James G.. - : The University of North Carolina at Chapel Hill University Libraries, 2016
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3
A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome
Mathias, Rasika Ann; Taub, Margaret A.; Gignoux, Christopher R.. - : Nature Publishing Group, 2016
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4
Fine-Scale Human Population Structure in Southern Africa Reflects Ecogeographic Boundaries
Uren, Caitlin; Kim, Minju; Martin, Alicia R.. - : Genetics Society of America, 2016
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5
History Shaped the Geographic Distribution of Genomic Admixture on the Island of Puerto Rico
Via i García, Marc; Gignoux, Christopher R.; Roth, Lindsey A.. - : Public Library of Science (PLoS), 2011
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