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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 4 of 4 1 Hybrid evolutionary techniques in feed forward neural network with distributed error for classification of handwritten Hindi SWARS Kumar, Somesh; Singh, Manu Pratap; Goel, Rajkumar... In: Connection science. - Abingdon, Oxfordshire : Taylor & Francis 25 (2013) 4, 197-215 OLC Linguistik Show details 2 Nonfluent/agrammatic PPA with in-vivo cortical amyloidosis and Pick's disease pathology. Caso, Francesca; Gesierich, Benno; Henry, Maya; Sidhu, Manu; LaMarre, Amanda; Babiak, Miranda; Miller, Bruce L; Rabinovici, Gil D; Huang, Eric J; Magnani, Giuseppe; Filippi, Massimo; Comi, Giancarlo; Seeley, William W; Gorno-Tempini, Maria Luisa In: Behavioural neurology, vol 26, iss 1-2 (2013) Abstract: The role of biomarkers in predicting pathological findings in the frontotemporal dementia (FTD) clinical spectrum disorders is still being explored. We present comprehensive, prospective longitudinal data for a 66 year old, right-handed female who met current criteria for the nonfluent/agrammatic variant of primary progressive aphasia (nfvPPA). She first presented with a 3-year history of progressive speech and language impairment mainly characterized by severe apraxia of speech. Neuropsychological and general motor functions remained relatively spared throughout the clinical course. Voxel-based morphometry (VBM) showed selective cortical atrophy of the left posterior inferior frontal gyrus (IFG) and underlying insula that worsened over time, extending along the left premotor strip. Five years after her first evaluation, she developed mild memory impairment and underwent PET-FDG and PiB scans that showed left frontal hypometabolism and cortical amyloidosis. Three years later (11 years from first symptom), post-mortem histopathological evaluation revealed Pick's disease, with severe degeneration of left IFG, mid-insula, and precentral gyrus. Alzheimer's disease (AD) (CERAD frequent/Braak Stage V) was also detected. This patient demonstrates that biomarkers indicating brain amyloidosis should not be considered conclusive evidence that AD pathology accounts for a typical FTD clinical/anatomical syndrome. Keyword: Aged; Alzheimer Disease; Amyloidosis; Aniline Compounds; apraxia of speech; Carbon Radioisotopes; Clinical Sciences; Cognitive Sciences; Disease Progression; Experimental Psychology; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Frontal Lobe; Frontotemporal dementia; Functional Neuroimaging; Humans; Magnetic Resonance Imaging; Neuropsychological Tests; Neurosciences; Nonfluent primary progressive aphasia; PiB-PET; Pick Disease of the Brain; Pick's disease; Positron-Emission Tomography; PPA; Primary Progressive Nonfluent Aphasia; Thiazoles; Voxel-based morphometry URL: https://escholarship.org/uc/item/8wt9b744 BASE Hide details 3 Nonfluent/agrammatic PPA with in-vivo cortical amyloidosis and Pick’s disease pathology Caso, Francesca; Gesierich, Benno; Henry, Maya. - 2013 BASE Show details 4 Using automated and fine-grained analysis of pronoun use as indicators of progress in an online collaborative project Thompson, Kate; Kennedy-Clark, Shannon; Kelly, Nick. - : Springer New York LLC, 2013 BASE Show details

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