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1
A Robust and Computationally Efficient Subspace-Based Fundamental Frequency Estimator
In: Institute of Electrical and Electronics Engineers. IEEE transactions on audio, speech and language processing. - New York, NY : Inst. 18 (2010) 3, 487-497
OLC Linguistik
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2
Diagnostic value of N-terminal pro-brain natriuretic peptide for pleural effusion due to heart failure: a meta-analysis
Zhou, Q; Ye, Z J; Su, Y. - : British Medical Journal Publishing Group, 2010
BASE
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3
Diagnostic value of N-terminal pro-brain natriuretic peptide for pleural effusion due to heart failure: a meta-analysis
Zhou, Q; Ye, Z J; Su, Y; Zhang, J C; Shi, H Z. - : BMJ Publishing Group Ltd, 2010
Abstract: Background N-terminal pro-brain natriuretic peptide (NT-proBNP) is a biomarker useful in diagnosis of pleural effusion due to heart failure. Thus far, its overall diagnostic accuracy has not been systematically reviewed. The aim of the present meta-analysis was to establish the overall diagnostic accuracy of the measurement of pleural NT-proBNP for identifying pleural effusion due to heart failure. Methods After a systematic review of English-language studies, sensitivity, specificity, and other measures of accuracy of NT-proBNP concentrations in pleural fluid in the diagnosis of pleural effusion resulting from heart failure were pooled using fixed-effects models. Summary receiver operating characteristic curves were used to summarise overall test performance. Results Eight publications met the inclusion criteria. The summary estimates for pleural NT-proBNP in the diagnosis of pleural effusion attributable to heart failure were: sensitivity 0.95 (95% CI 0.92 to 0.97), specificity 0.94 (0.92 to 0.96), positive likelihood ratio 14.12 (10.23 to 19.51), negative likelihood ratio 0.06 (0.04 to 0.09) and diagnostic OR 213.87 (122.50 to 373.40). Conclusions NT-proBNP levels in pleural fluid showed a high diagnostic accuracy and may help accurately differentiate cardiac from non-cardiac conditions in patients presenting with pleural effusion.
Keyword: Heart failure
URL: http://heart.bmj.com/cgi/content/short/96/15/1207
https://doi.org/10.1136/hrt.2009.188474
BASE
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