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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 8 of 8 1 Your mum! Teenagers' swearing by mother in English, Spanish and Norwegian Drange, Eli-Marie Danbolt; Hasund, Ingrid Kristine; Stenström, Anna-Brita In: International journal of corpus linguistics. - Amsterdam [u.a.] : Benjamins 19 (2014) 1, 29-59 OLC Linguistik Show details 2 Coding causal–noncausal verb alternations: A form–frequency correspondence explanation – CORRIGENDUM HASPELMATH, MARTIN; CALUDE, ANDREEA; SPAGNOL, MICHAEL... In: Journal of linguistics. - London [u.a.] : Cambridge Univ. Press 50 (2014) 3, 779 OLC Linguistik Show details 3 A test case for an optimality-theoretic approach to left-edge metathesis Asikin-Garmager, Eli In: Proceedings of the forty-ninth (49.) annual meeting of the Chicago Linguistic Society (2014), S. 1-16 Leibniz-Zentrum Allgemeine Sprachwissenschaft Show details 4 COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites Cradick, Thomas J; Qiu, Peng; Lee, Ciaran M; Fine, Eli J; Bao, Gang. - : Nature Publishing Group, 2014 Abstract: Precise genome editing using engineered nucleases can significantly facilitate biological studies and disease treatment. In particular, clustered regularly interspaced short palindromic repeats (CRISPR) with CRISPR-associated (Cas) proteins are a potentially powerful tool for modifying a genome by targeted cleavage of DNA sequences complementary to designed guide strand RNAs. Although CRISPR/Cas systems can have on-target cleavage rates close to the transfection rates, they may also have relatively high off-target cleavage at similar genomic sites that contain one or more base pair mismatches, and insertions or deletions relative to the guide strand. We have developed a bioinformatics-based tool, COSMID (CRISPR Off-target Sites with Mismatches, Insertions, and Deletions) that searches genomes for potential off-target sites (http://crispr.bme.gatech.edu). Based on the user-supplied guide strand and input parameters, COSMID identifies potential off-target sites with the specified number of mismatched bases and insertions or deletions when compared with the guide strand. For each site, amplification primers optimal for the chosen application are also given as output. This ranked-list of potential off-target sites assists the choice and evaluation of intended target sites, thus helping the design of CRISPR/Cas systems with minimal off-target effects, as well as the identification and quantification of CRISPR/Cas induced off-target cleavage in cells. Keyword: Original Article URL: http://www.ncbi.nlm.nih.gov/pubmed/25462530 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272406 https://doi.org/10.1038/mtna.2014.64 BASE Hide details 5 An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage Fine, Eli J.; Cradick, Thomas J.; Zhao, Charles L.. - : Oxford University Press, 2014 BASE Show details 6 Philological analysis of Old Mongolian: consonant-vowel harmony was not universally enforced ... Hornstein, Eli D.. - : The University of North Carolina at Chapel Hill University Libraries, 2014 BASE Show details 7 Tongue papillae morphology of brown-throated sloth Bradypus variegatus (SCHINZ, 1825) Martins, D. M; Pinheiro, L. L; Ferreira, V. C. - 2014 BASE Show details 8 Formação de leitores surdos e a educação inclusiva Martins, Sandra Eli Sartoreto de Oliveira. - : Universidade Estadual Paulista (UNESP), 2014 BASE Show details

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