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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 5 of 5 1 Lost for emotion words: What motor and limbic brain activity reveals about autism and semantic theory Moseley, Rachel L.; Shtyrov, Yury; Mohr, Bettina; Lombardo, Michael V.; Baron-Cohen, Simon; Pulvermüller, Friedemann. - : Academic Press, 2015 Abstract: Autism spectrum conditions (ASC) are characterised by deficits in understanding and expressing emotions and are frequently accompanied by alexithymia, a difficulty in understanding and expressing emotion words. Words are differentially represented in the brain according to their semantic category and these difficulties in ASC predict reduced activation to emotion-related words in limbic structures crucial for affective processing. Semantic theories view ‘emotion actions’ as critical for learning the semantic relationship between a word and the emotion it describes, such that emotion words typically activate the cortical motor systems involved in expressing emotion actions such as facial expressions. As ASC are also characterised by motor deficits and atypical brain structure and function in these regions, motor structures would also be expected to show reduced activation during emotion-semantic processing. Here we used event-related fMRI to compare passive processing of emotion words in comparison to abstract verbs and animal names in typically-developing controls and individuals with ASC. Relatively reduced brain activation in ASC for emotion words, but not matched control words, was found in motor areas and cingulate cortex specifically. The degree of activation evoked by emotion words in the motor system was also associated with the extent of autistic traits as revealed by the Autism Spectrum Quotient. We suggest that hypoactivation of motor and limbic regions for emotion word processing may underlie difficulties in processing emotional language in ASC. The role that sensorimotor systems and their connections might play in the affective and social-communication difficulties in ASC is discussed. Keyword: Article URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265725 http://www.ncbi.nlm.nih.gov/pubmed/25278250 https://doi.org/10.1016/j.neuroimage.2014.09.046 BASE Hide details 2 Neuroanatomy of Individual Differences in Language in Adult Males with Autism Lai, Meng-Chuan; Lombardo, Michael V.; Ecker, Christine. - : Oxford University Press, 2015 BASE Show details 3 Neuroanatomy of Individual Differences in Language in Adult Males with Autism Lai, Meng-Chuan; Lombardo, Michael V.; Ecker, Christine. - : Oxford University Press, 2015 BASE Show details 4 Lost for emotion words: what motor and limbic brain activity reveals about autism and semantic theory Moseley, Rachel L.; Shtyrov, Yury; Mohr, Bettina. - : Elsevier, 2015 BASE Show details 5 A pooled genome-wide association study of Asperger Syndrome Warrier, Varun; Chakrabarti, Bhismadev; Murphy, Laura. - : Public Library of Science, 2015 BASE Show details

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