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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 6 of 6 1 Leveraging Lexical Link Analysis (LLA) to discover new knowledge Zhao, Ying; Mackinnon, Douglas J.; Gallup, Shelley P.. - : The Journal of the Military Cyber Professionals Association, 2016 BASE Show details 2 Functional Anatomy of Recognition of Chinese Multi-Character Words: Convergent Evidence from Effects of Transposable Nonwords, Lexicality, and Word Frequency Yu, Xi; Lin, Nan; Zhang, Mingxia. - : Public Library of Science, 2016 BASE Show details 3 Diabetes and Hypertension Consistently Predict the Presence and Extent of Coronary Artery Calcification in Symptomatic Patients: A Systematic Review and Meta-Analysis Nicoll, Rachel; Zhao, Ying; Ibrahimi, Pranvera. - : MDPI, 2016 BASE Show details 4 Leveraging Lexical Link Analysis (LLA) To Discover New Knowledge Zhao, Ying; MacKinnon, Douglas J.; Gallup, Shelley P.... In: Military Cyber Affairs (2016) BASE Show details 5 Cis-regulatory architecture of a brain-signaling center predates the origin of chordates Yao, Yao; Minor, Paul J.; Zhao, Ying-Tao; Jeong, Yongsu; Pani, Ariel M.; King, Anna N.; Symmons, Orsolya; Gan, Lin; Cardoso, Wellington V.; Spitz, François; Lowe, Christopher J.; Epstein, Douglas J.. - 2016 Abstract: Genomic approaches have predicted hundreds of thousands of tissue specific cis-regulatory sequences, but the determinants critical to their function and evolutionary history are mostly unknown1–4. Here, we systematically decode a set of brain enhancers active in the zona limitans intrathalamica (zli), a signaling center essential for vertebrate forebrain development via the secreted morphogen, Sonic hedgehog (Shh)5,6. We apply a de novo motif analysis tool to identify six position-independent sequence motifs together with their cognate transcription factors that are essential for zli enhancer activity and Shh expression in the mouse embryo. Using knowledge of this regulatory lexicon, we discover novel Shh zli enhancers in mice, and a functionally equivalent element in hemichordates, indicating an ancient origin of the Shh zli regulatory network that predates the chordate phylum. These findings support a strategy for delineating functionally conserved enhancers in the absence of overt sequence homologies, and over extensive evolutionary distances. Keyword: Article URL: https://doi.org/10.1038/ng.3542 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848136/ http://www.ncbi.nlm.nih.gov/pubmed/27064252 BASE Hide details 6 Functional Anatomy of Recognition of Chinese Multi-Character Words: Convergent Evidence from Effects of Transposable Nonwords, Lexicality, and Word Frequency Lin, Nan; Yu, Xi; Zhao, Ying. - : Public Library of Science, 2016 BASE Show details

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