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Sensitivity and specificity of an acoustic- and perceptual-based tool for assessing motor speech disorders in French: the MonPaGe -screening protocol
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In: ISSN: 0269-9206 ; EISSN: 1464-5076 ; Clinical Linguistics & Phonetics ; https://hal.archives-ouvertes.fr/hal-03099545 ; Clinical Linguistics & Phonetics, Taylor & Francis, In press, ⟨10.1080/02699206.2020.1865460⟩ (2021)
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Analysing spectral changes over time to identify articulatory impairments in dysarthria
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In: ISSN: 0001-4966 ; EISSN: 1520-8524 ; Journal of the Acoustical Society of America ; https://hal.archives-ouvertes.fr/hal-03099517 ; Journal of the Acoustical Society of America, Acoustical Society of America, 2021, 149 (2), pp.758 - 769. ⟨10.1121/10.0003332⟩ (2021)
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Attention in post-lexical processes of utterance production: Dual-task cost in younger and older adults ...
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Attention in post-lexical processes of utterance production: Dual-task cost in younger and older adults ...
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sj-docx-1-qjp-10.1177_17470218211034130 – Supplemental material for Attention in post-lexical processes of utterance production: Dual-task cost in younger and older adults ...
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sj-docx-1-qjp-10.1177_17470218211034130 – Supplemental material for Attention in post-lexical processes of utterance production: Dual-task cost in younger and older adults ...
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Attention in post-lexical processes of utterance production: Dual-task cost in younger and older adults
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In: Q J Exp Psychol (Hove) (2021)
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Attention in post-lexical processes of utterance production: dual-task cost in younger and older adults
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In: ISSN: 1747-0218 ; The quarterly journal of experimental psychology, Vol. 74, No 11 (2021) pp. 1852-1872 (2021)
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Analysing spectral changes over time to identify articulatory impairments in dysarthria
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In: ISSN: 0001-4966 ; Journal of the Acoustical Society of America, Vol. 149, No 2 (2021) pp. 758-769 (2021)
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Sensitivity and specificity of an acoustic- and perceptual-based tool for assessing motor speech disorders in French: the MonPaGe-screening protocol
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In: ISSN: 0269-9206 ; Clinical Linguistics and Phonetics (2021) pp. 1-16 (2021)
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Using spectral features to distinguish speakers with Parkinson’s disease from typical speakers
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In: 12th International Seminar on Speech Production ; https://hal.archives-ouvertes.fr/hal-03099425 ; 12th International Seminar on Speech Production, Dec 2020, Providence, United States (2020)
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MonPaGe, un outil de screening francophone informatisé d’évaluation perceptive et acoustique des troubles moteurs de la parole (dysarthries, apraxie de la parole
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In: ISSN: 0034-222X ; Rééducation orthophonique ; https://halshs.archives-ouvertes.fr/halshs-02504027 ; Rééducation orthophonique, Ortho édition, 2020, 281, pp.171-197 (2020)
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DUAL-TASK EFFECTS ON SPEECH AND NON-VERBAL TASKS ACCORDING TO TASKS PROPERTIES
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In: Proceedings of the 19th International Congress of Phonetic Sciences ; 19th International Congress of Phonetic Sciences ; https://hal.archives-ouvertes.fr/hal-02427703 ; 19th International Congress of Phonetic Sciences, 2019, Melbourne, Australia (2019)
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Anticipatory VtoV coarticulation in French in several Motor Speech Disorders.
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In: Phonetics and Phonology in Europe (PAPE 2019) ; https://hal.archives-ouvertes.fr/hal-02427864 ; Phonetics and Phonology in Europe (PAPE 2019), Jun 2019, Lecce, Italy (2019)
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Effet du sexe, de l’âge et de la variété régionale sur l’établissement de valeurs normatives pour le protocole MonPaGe
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In: Journées de Phonétique Clinique ; https://hal.archives-ouvertes.fr/hal-02427871 ; Journées de Phonétique Clinique, May 2019, Mons, Belgique (2019)
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Coarticulation anticipatoire dans différents Troubles Moteurs de la Parole
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In: Journées de Phonétique Clinique ; https://hal.archives-ouvertes.fr/hal-02427856 ; Journées de Phonétique Clinique, May 2019, Mons, Belgique (2019)
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Contribution of acoustic analysis in the differential diagnosis of apraxia of speech
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In: Stem-Spraak-en Taalpathologie ; https://hal.archives-ouvertes.fr/hal-02428255 ; Stem-Spraak-en Taalpathologie, 2019, 24 (S1), pp.106-107 (2019)
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Validation en région Lémanique du protocole informatisé d'évaluation de la parole MonPaGe
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In: Questions de Phonétique Clinique ; https://hal.archives-ouvertes.fr/hal-02427867 ; Questions de Phonétique Clinique, May 2019, Mons, Belgium. 69 (2019)
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Mesures de performance en production, de l’effet de la tâche et de l’attention sur les paramètres temporels de la parole de locuteurs contrôles et de locuteurs dysarthriques wilsoniens
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In: 7èmesJournées de Phonétique Clinique ; https://hal.archives-ouvertes.fr/hal-02437323 ; 7èmesJournées de Phonétique Clinique, 2017, Paris, France (2017)
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Dystonic Dysarthria in Wilson Disease: Efficacy of Zolpidem
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Abstract:
Wilson disease (WD) is a rare genetic disorder characterized by copper overload in the liver and the brain. Neurological presentations are mainly related to the accumulation of copper in the basal ganglia, the brainstem, and the cerebellum. Dysarthria is a frequent symptom, with dystonic, spastic, or parkinsonian components and is usually resistant to medical or voice rehabilitation therapies. Here, we report the case of a patient with WD diagnosed at the age of 12, who presented a severe and constant dysarthria from dystonic origin which was unresponsive to benzodiazepines and anticholinergic drugs. When she was 25-year-old, she tried zolpidem at bedtime for sleeping difficulties and reported a paradoxical effect of this drug on her voice. To confirm the effect of zolpidem on her dystonic dysarthria, we realized a full evaluation of her dysarthria at baseline without zolpidem and after 4 days of treatment by 10 mg twice a day. Lexical access was evaluated by the semantic fluency; dysarthria by the Intelligibility Score, the spontaneous speech and reading rates, the maximum phonation time on the sustained vowel [a] and by a perceptive evaluation. Two hours after the intake of zolpidem, improvement of all the parameters tested, with the exception of the maximum phonation time, was observed. Semantic fluency increased by 59%, the spontaneous speech rate by 88% and the reading rate by 76%. General dystonia remained unchanged and the tolerance of zolpidem was satisfactory. Since then, the patient takes zolpidem 5 mg five times a day, and 4 years later shows persistent improvement in oral communication and a good drug tolerance. In this single-case study, we showed that regular daytime intake of zolpidem could have a persisting effect on a complex dystonic dysarthria that was resistant to usual medical treatments.
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Keyword:
Neuroscience
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URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671475/ https://doi.org/10.3389/fneur.2017.00559 http://www.ncbi.nlm.nih.gov/pubmed/29163329
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