DE eng

Search in the Catalogues and Directories

Hits 1 – 10 of 10

1
Impact of early valve surgery on outcome of Staphylococcus aureus prosthetic valve infective endocarditis: analysis in the international collaboration of Endocarditis-Prospective Cohort Study
Chirouze, C.; Alla, F.; Fowler, V.G.. - : University of Chicago Press, 2015
BASE
Show details
2
Impact of early valve surgery on outcome of Staphylococcus aureus prosthetic valve infective endocarditis: analysis in the International Collaboration of Endocarditis-Prospective Cohort Study.
In: Clinical Infectious Diseases, vol. 60, no. 5, pp. 741-749 (2015)
BASE
Show details
3
Influence of the timing of cardiac surgery on the outcome of patients with infective endocarditis and stroke.
In: Clinical Infectious Diseases, vol. 56, no. 2, pp. 209-217 (2013)
BASE
Show details
4
In-hospital and 1-year mortality in patients undergoing early surgery for prosthetic valve endocarditis.
In: JAMA Internal Medicine, vol. 173, no. 16, pp. 1495-1504 (2013)
Abstract: IMPORTANCE: There are limited prospective, controlled data evaluating survival in patients receiving early surgery vs medical therapy for prosthetic valve endocarditis (PVE). OBJECTIVE: To determine the in-hospital and 1-year mortality in patients with PVE who undergo valve replacement during index hospitalization compared with patients who receive medical therapy alone, after controlling for survival and treatment selection bias. DESIGN, SETTING, AND PARTICIPANTS: Participants were enrolled between June 2000 and December 2006 in the International Collaboration on Endocarditis-Prospective Cohort Study (ICE-PCS), a prospective, multinational, observational cohort of patients with infective endocarditis. Patients hospitalized with definite right- or left-sided PVE were included in the analysis. We evaluated the effect of treatment assignment on mortality, after adjusting for biases using a Cox proportional hazards model that included inverse probability of treatment weighting and surgery as a time-dependent covariate. The cohort was stratified by probability (propensity) for surgery, and outcomes were compared between the treatment groups within each stratum. INTERVENTIONS: Valve replacement during index hospitalization (early surgery) vs medical therapy. MAIN OUTCOMES AND MEASURES: In-hospital and 1-year mortality. RESULTS: Of the 1025 patients with PVE, 490 patients (47.8%) underwent early surgery and 535 individuals (52.2%) received medical therapy alone. Compared with medical therapy, early surgery was associated with lower in-hospital mortality in the unadjusted analysis and after controlling for treatment selection bias (in-hospital mortality: hazard ratio [HR], 0.44 [95% CI, 0.38-0.52] and lower 1-year mortality: HR, 0.57 [95% CI, 0.49-0.67]). The lower mortality associated with surgery did not persist after adjustment for survivor bias (in-hospital mortality: HR, 0.90 [95% CI, 0.76-1.07] and 1-year mortality: HR, 1.04 [95% CI, 0.89-1.23]). Subgroup analysis indicated a lower in-hospital mortality with early surgery in the highest surgical propensity quintile (21.2% vs 37.5%; P = .03). At 1-year follow-up, the reduced mortality with surgery was observed in the fourth (24.8% vs 42.9%; P = .007) and fifth (27.9% vs 50.0%; P = .007) quintiles of surgical propensity. CONCLUSIONS AND RELEVANCE: Prosthetic valve endocarditis remains associated with a high 1-year mortality rate. After adjustment for differences in clinical characteristics and survival bias, early valve replacement was not associated with lower mortality compared with medical therapy in the overall cohort. Further studies are needed to define the effect and timing of surgery in patients with PVE who have indications for surgery.
Keyword: Aortic Valve/surgery; Bacterial/mortality; Bacterial/therapy; Endocarditis; Female; Follow-Up Studies; Heart Valve Prosthesis Implantation; Heart Valve Prosthesis/adverse effects; Hospital Mortality; Humans; Male; Middle Aged; Mitral Valve/surgery; Propensity Score; Proportional Hazards Models; Prospective Studies; Prosthesis-Related Infections/mortality; Prosthesis-Related Infections/therapy; Registries; Time-to-Treatment
URL: https://serval.unil.ch/notice/serval:BIB_FC667FBDEF40
https://doi.org/10.1001/jamainternmed.2013.8203
BASE
Hide details
5
Enterococcal endocarditis in the beginning of the 21st century: analysis from the International Collaboration on Endocarditis-Prospective Cohort Study.
In: Clinical Microbiology and Infection, vol. 19, no. 12, pp. 1140-1147 (2013)
BASE
Show details
6
HACEK infective endocarditis: characteristics and outcomes from a large, multi-national cohort.
In: PLoS One, vol. 8, no. 5, pp. e63181 (2013)
BASE
Show details
7
Clinical characteristics and outcome of infective endocarditis involving implantable cardiac devices.
In: Journal of the American Medical Association, vol. 307, no. 16, pp. 1727-1735 (2012)
BASE
Show details
8
Health care-associated native valve endocarditis: importance of non-nosocomial acquisition.
In: Annals of Internal Medicine, vol. 150, no. 9, pp. 586-594 (2009)
BASE
Show details
9
Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study.
In: Archives of internal medicine, vol. 169, no. 5, pp. 463-473 (2009)
BASE
Show details
10
Current features of infective endocarditis in elderly patients: results of the International Collaboration on Endocarditis Prospective Cohort Study.
In: Archives of Internal Medicine, vol. 168, no. 19, pp. 2095-2103 (2008)
BASE
Show details

Catalogues
0
0
0
0
0
0
0
Bibliographies
0
0
0
0
0
0
0
0
0
Linked Open Data catalogues
0
Online resources
0
0
0
0
Open access documents
10
0
0
0
0
© 2013 - 2024 Lin|gu|is|tik | Imprint | Privacy Policy | Datenschutzeinstellungen ändern