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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 2 of 2 1 Structural and Functional Reorganization of the Corpus Callosum between the Age of 6 and 8 Years Westerhausen, René; Luders, Eileen; Specht, Karsten. - : Oxford University Press, 2011 BASE Show details 2 Structural and Functional Reorganization of the Corpus Callosum between the Age of 6 and 8 Years Westerhausen, René; Luders, Eileen; Specht, Karsten; Ofte, Sonja H.; Toga, Arthur W.; Thompson, Paul M.; Helland, Turid; Hugdahl, Kenneth. - : Oxford University Press, 2011 Abstract: The establishment of an efficient exchange of information between the cerebral hemispheres is of crucial importance in the developing functionally lateralized brain. The corpus callosum, the major connection between the cerebral hemispheres, grows constantly throughout childhood and adolescence. However, behavioral studies suggest the existence of a critical time period for callosal functional development starting around the age of 6 years. In the present longitudinal study, examining a cohort of 20 children at the age of 6 and 8 years, we assessed the relationship between structural and functional callosal development during this time period. The structural development was quantified by calculating the increase in callosal thickness using a shape-based computational analysis of the mid-sagittal corpus callosum as obtained with magnetic resonance imaging. The functional development was assessed with a speech discrimination task based on the dichotic presentation of consonant–vowel syllables. The statistical analysis revealed that children whose callosal isthmus increased in thickness over the course of 2 years showed a decrease in interhemispheric information transfer. However, children exhibiting a decrease in isthmus thickness revealed an increase in information transfer. These results might indicate a refinement process of the callosal connections to optimize the neuronal communication between the developing cerebral hemispheres. Keyword: Articles URL: http://www.ncbi.nlm.nih.gov/pubmed/20847151 https://doi.org/10.1093/cercor/bhq165 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077426 BASE Hide details

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