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1
Findings of Impaired Hearing in Patients With Nonfluent/Agrammatic Variant Primary Progressive Aphasia.
Hardy, CJD; Frost, C; Sivasathiaseelan, H. - : American Medical Association, 2019
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2
Impaired Interoceptive Accuracy in Semantic Variant Primary Progressive Aphasia
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3
Behavioural and neuroanatomical correlates of auditory speech analysis in primary progressive aphasias
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4
Primary progressive aphasia: a clinical approach
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5
The TMEM106B risk allele is associated with lower cortical volumes in a clinically diagnosed frontotemporal dementia cohort.
In: J Neurol Neurosurg Psychiatry (2017) (2017)
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6
Processing emotion from abstract art in frontotemporal lobar degeneration
In: Neuropsychologia , 81 pp. 245-254. (2016) (2016)
Abstract: art may signal emotions independently of a biological or social carrier: it might therefore constitute a test case for defining brain mechanisms of generic emotion decoding and the impact of disease states on those mechanisms. This is potentially of particular relevance to diseases in the frontotemporal lobar degeneration (FTLD) spectrum. These diseases are often led by emotional impairment despite retained or enhanced artistic interest in at least some patients. However, the processing of emotion from art has not been studied systematically in FTLD. Here we addressed this issue using a novel emotional valence matching task on abstract paintings in patients representing major syndromes of FTLD (behavioural variant frontotemporal dementia, n=11; sematic variant primary progressive aphasia (svPPA), n=7; nonfluent variant primary progressive aphasia (nfvPPA), n=6) relative to healthy older individuals (n=39). Performance on art emotion valence matching was compared between groups taking account of perceptual matching performance and assessed in relation to facial emotion matching using customised control tasks. Neuroanatomical correlates of art emotion processing were assessed using voxel-based morphometry of patients' brain MR images. All patient groups had a deficit of art emotion processing relative to healthy controls; there were no significant interactions between syndromic group and emotion modality. Poorer art emotion valence matching performance was associated with reduced grey matter volume in right lateral occopitotemporal cortex in proximity to regions previously implicated in the processing of dynamic visual signals. Our findings suggest that abstract art may be a useful model system for investigating mechanisms of generic emotion decoding and aesthetic processing in neurodegenerative diseases.
Keyword: Art; Emotion; Frontotemporal lobar degeneration; Semantic dementia
URL: http://discovery.ucl.ac.uk/1482261/1/Processing%20emotion%20from%20abstract%20art%20in%20frontotemporal%20lobar%20degeneration.pdf
http://discovery.ucl.ac.uk/1482261/7/mmc1-3.pdf
http://discovery.ucl.ac.uk/1482261/
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7
Binary reversals in primary progressive aphasia
In: Cortex , 82 pp. 287-289. (2016) (2016)
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8
Pain and temperature processing in dementia: a clinical and neuroanatomical analysis
In: Brain , 138 (11) pp. 3360-3372. (2015) (2015)
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9
The Language Profile of Behavioral Variant Frontotemporal Dementia
In: Journal of Alzheimer's Disease , 50 (2) pp. 359-371. (2015) (2015)
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10
Delayed auditory feedback simulates features of nonfluent primary progressive aphasia.
In: J Neurol Sci , 347 (1-2) 345 - 348. (2014) (2014)
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11
Delayed auditory feedback simulates features of nonfluent primary progressive aphasia
In: Journal of the Neurological Sciences , 347 (1-2) 345 - 348. (2014) (2014)
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12
Patterns of longitudinal brain atrophy in the logopenic variant of primary progressive aphasia
In: Brain and Language , 127 (2) 121 - 126. (2013) (2013)
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13
Exome sequencing reveals a novel partial deletion in the progranulin gene causing primary progressive aphasia.
In: J Neurol Neurosurg Psychiatry , 84 (12) pp. 1411-1412. (2013) (2013)
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14
Frontotemporal dementia
In: BMJ , 347 , Article f4827 . (2013) (2013)
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15
PARIETAL CONTRIBUTIONS TO LANGUAGE PROCESSING: PROGRESSIVE APHASIA IN POSTERIOR CORTICAL ATROPHY
Crutch, S; Lehmann, M; Warrington, EK. - : BMJ Publishing Group Ltd, 2012
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16
Alzheimer's pathology in primary progressive aphasia.
In: Neurobiol Aging , 33 (4) pp. 744-752. (2012) (2012)
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17
PARIETAL CONTRIBUTIONS TO LANGUAGE PROCESSING: PROGRESSIVE APHASIA IN POSTERIOR CORTICAL ATROPHY
In: In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (2012) (2012)
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18
Receptive prosody in nonfluent primary progressive aphasias.
In: Cortex , 48 (3) 308 - 316. (2012) (2012)
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19
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia
In: BRAIN , 134 2456 - 2477. (2011) (2011)
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20
Apraxia in progressive nonfluent aphasia
In: J NEUROL , 257 (4) 569 - 574. (2010) (2010)
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