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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 17 of 17 1 Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers. Lee, Suzee E; Sias, Ana C; Kosik, Eena L. - : eScholarship, University of California, 2019 BASE Show details 2 Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers. Lee, Suzee E; Sias, Ana C; Kosik, Eena L... In: Lee, Suzee E; Sias, Ana C; Kosik, Eena L; Flagan, Taru M; Deng, Jersey; Chu, Stephanie A; et al.(2019). Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers. NeuroImage. Clinical, 22, 101751. doi:10.1016/j.nicl.2019.101751. UCLA: Retrieved from: http://www.escholarship.org/uc/item/6vv8g8qt (2019) BASE Show details 3 Factors that predict diagnostic stability in neurodegenerative dementia. Perry, David C; Datta, Samir; Miller, Zachary A; Rankin, Katherine P; Gorno-Tempini, Maria Luisa; Kramer, Joel H; Rosen, Howard J; Seeley, William W; Miller, Bruce L In: Journal of neurology, vol 266, iss 8 (2019) Abstract: ObjectiveTo determine the frequency and characteristics of clinical diagnostic change in frontotemporal dementia (FTD)-spectrum syndromes and Alzheimer's disease (AD)-type dementia.MethodsWe reviewed records and categorized diagnostic changes in patients seen ≥ 2 times with behavioral variant FTD (bvFTD, n = 99), nonfluent and semantic variant primary progressive aphasia (nfvPPA, n = 32; svPPA, n = 59), corticobasal syndrome (CBS, n = 40), progressive supranuclear palsy-Richardson syndrome (PSP-RS, n = 34), and AD-type dementia (n = 49). For bvFTD, we compared patients with and without diagnostic change, and assessed predictors of diagnostic change by logistic regression.ResultsInitial diagnoses changed infrequently at subsequent visits in svPPA (6.8%), PSP-RS (8.8%), and nfvPPA (12.5%), with rare changes largely involving clinicopathological overlap or diagnostic ambiguity. Changes in AD-type dementia (30.6%) and CBS (37.5%) were more common, but reflected greater specificity, predicted co-pathology, or overlapping syndromes. Diagnostic change in bvFTD was also common (32.3%), but more diverse, including motor neuron disease development, alternative neurodegenerative syndromes, and non-neurodegenerative diseases. Diagnostic change occurred more often in those who met possible rather than probable bvFTD criteria (70.6% vs 15.3%, p < 0.001). Patients with stable diagnoses showed greater overall impairment, bvFTD behavioral severity, and atrophy in core right-hemisphere bvFTD regions. Patients with diagnostic change had more severe depression (p < 0.05) and more frequent contributing, secondary diagnoses (p = 0.01), such as cerebrovascular disease. By logistic regression, the accuracy of predicting stable bvFTD diagnoses using first-visit data was 80%.ConclusionbvFTD displays more diverse diagnostic change than other neurodegenerative syndromes. First-visit bvFTD diagnoses may waver if based on meeting possible criteria only. Keyword: Acquired Cognitive Impairment; Aged; Aging; Alzheimer Disease; Alzheimer's disease; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Alzheimer's Disease Related Dementias (ADRD); Alzheimer’s disease; Aphasia; Brain Disorders; Clinical Research; Clinical Sciences; Corticobasal degeneration; Dementia; Female; Frontotemporal Dementia; Frontotemporal Dementia (FTD); Humans; Male; Middle Aged; Neurodegenerative; Neurodegenerative Diseases; Neurological; Neurology & Neurosurgery; Neurosciences; Predictive Value of Tests; Primary Progressive; Progressive; Progressive supranuclear palsy; Rare Diseases; Retrospective Studies; Supranuclear Palsy URL: https://escholarship.org/uc/item/4rz1t2j1 BASE Hide details 4 Factors that predict diagnostic stability in neurodegenerative dementia. Perry, David C; Datta, Samir; Miller, Zachary A... In: Journal of neurology, vol 266, iss 8 (2019) BASE Show details 5 Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia. Miller, Zachary A; Spina, Salvatore; Pakvasa, Mikhail... In: Brain communications, vol 1, iss 1 (2019) BASE Show details 6 Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers. Lee, Suzee E; Sias, Ana C; Kosik, Eena L. - : eScholarship, University of California, 2019 BASE Show details 7 Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia. Miller, Zachary A; Spina, Salvatore; Pakvasa, Mikhail... In: Brain communications, vol 1, iss 1 (2019) BASE Show details 8 Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia Miller, Zachary A; Spina, Salvatore; Pakvasa, Mikhail... In: Brain Commun (2019) BASE Show details 9 Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory. Ljubenkov, Peter A; Staffaroni, Adam M; Rojas, Julio C... In: Annals of clinical and translational neurology, vol 5, iss 10 (2018) BASE Show details 10 Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia. Santos-Santos, Miguel A; Rabinovici, Gil D; Iaccarino, Leonardo... In: JAMA neurology, vol 75, iss 3 (2018) BASE Show details 11 Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia. Santos-Santos, Miguel A; Rabinovici, Gil D; Iaccarino, Leonardo... In: JAMA neurology, vol 75, iss 3 (2018) BASE Show details 12 Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory. Ljubenkov, Peter A; Staffaroni, Adam M; Rojas, Julio C... In: Annals of clinical and translational neurology, vol 5, iss 10 (2018) BASE Show details 13 Typical and atypical pathology in primary progressive aphasia variants Spinelli, Edoardo G; Mandelli, Maria Luisa; Miller, Zachary A. - 2017 BASE Show details 14 Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture. Miller, Zachary A; Sturm, Virginia E; Camsari, Gamze Balci... In: Neurology(R) neuroimmunology & neuroinflammation, vol 3, iss 6 (2016) BASE Show details 15 Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture. Miller, Zachary A; Sturm, Virginia E; Camsari, Gamze Balci... In: Neurology(R) neuroimmunology & neuroinflammation, vol 3, iss 6 (2016) BASE Show details 16 Atrophy patterns in early clinical stages across distinct phenotypes of Alzheimer's disease. Ossenkoppele, Rik; Cohn-Sheehy, Brendan I; La Joie, Renaud... In: Human brain mapping, vol 36, iss 11 (2015) BASE Show details 17 Atrophy patterns in early clinical stages across distinct phenotypes of Alzheimer's disease. Ossenkoppele, Rik; Cohn-Sheehy, Brendan I; La Joie, Renaud... In: Human brain mapping, vol 36, iss 11 (2015) BASE Show details

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