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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 5 of 5 1 Semantic activation in Parkinson's disease patients on and off levodopa Angwin, Anthony J.; Arnott, Wendy L.; Copland, David A.. - : Elsevier Masson, 2009 BASE Show details 2 Dopaminergic neuromodulation of semantic processing: A 4-T fMRI study with levodopa Copland, David A.; McMahon, Katie L.; Silburn, Peter A.; de Zubicaray, Greig I.. - : Oxford University Press., 2009 Abstract: There is emerging evidence that alterations in dopaminergic transmission can influence semantic processing, yet the neural mechanisms involved are unknown. The influence of levodopa (L-DOPA) on semantic priming was investigated in healthy individuals (n = 20) using event-related functional magnetic resonance imaging with a randomized, double-blind crossover design. Critical prime-target pairs consisted of a lexical ambiguity prime and 1) a target related to the dominant meaning of the prime (e.g., bank-money), 2) a target related to the subordinate meaning (e.g., fence-sword), or 3) an unrelated target (e.g., ball-desk). Behavioral data showed that both dominant and subordinate meanings were primed on placebo. In contrast, there was preserved priming of dominant meanings and no significant priming of subordinate meanings on L-DOPA, the latter associated with decreased anterior cingulate and dorsal prefrontal cortex activity. Dominant meaning activation on L-DOPA was associated with increased activity in the left rolandic operculum and left middle temporal gyrus. These findings suggest that L-DOPA enhances frequency-based semantic focus via prefrontal and temporal modulation of automatic semantic priming and through engagement of anterior cingulate mechanisms supporting attentional/controlled priming. Keyword: 170101 Biological Psychology (Neuropsychology; 170204 Linguistic Processes (incl. Speech Production and Comprehension); Activation; Ambiguous Words; Brain Activity; Brain imaging; C1; cognitive function; Cortex; Dopamine; Event-related Fmri; fMRI; Functional Mri; Language; Lexical ambiguity; Modulation; Parkinsons-disease; Physiological Psychology); Psychopharmacology; Semantic priming; Working-memory URL: https://espace.library.uq.edu.au/view/UQ:189707 BASE Hide details 3 The speed of lexical activation is altered in Parkinson's disease Angwin, Anthony J.; Chenery, Helen J.; Copland, David A.. - : Taylor & Francis Inc, 2007 BASE Show details 4 Self-paced reading and sentence comprehension in Parkinson's disease Angwin, Anthony J.; Chenery, Helen J.; Copland, David A.. - : Pergamon, 2006 BASE Show details 5 Summation of semantic priming and complex sentence comprehension in Parkinson's disease Angwin, Anthony J.; Chenery, Helen J.; Copland, David A.. - : Elsevier Science, 2005 BASE Show details

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